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Renal epithelioid angiomyolipoma: MRI findings

  • ABDOMINAL RADIOLOGY
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Abstract

Purpose

To retrospectively analyze the MR imaging presentation of renal epithelioid angiomyolipoma (EAML).

Methods

Retrospective analysis revealed 12 subjects with histologically proven renal EAML who underwent preoperative MRI at our institution between January 2009 and June 2016. Two radiologists reviewed the images in consensus, describing MR imaging features including size, location, growth pattern, signal intensity of tumor, and dynamic enhancement pattern.

Results

Nine women and three men were included. The average maximum tumor diameter was 7.1 cm. Exophytic growth was present in 9/12 cases, mesophytic growth in 2/12, and endophytic growth in 1/12. On T1-weighted images, 2/12 displayed homogeneous isointensity, 1/12 homogeneous hyperintensity, 5/12 heterogeneous hypointensity, and 4/12 heterogeneous hyperintensity. Macroscopic fat was detected in 5/12 cases and microscopic fat in 6/12 cases. On T2-weighted images, 5/12 showed heterogeneous hypointensity, 4/12 heterogeneous hyperintensity, and 3/12 homogeneous hypointensity. On dynamic contrast-enhanced MR images, 7/12 showed a slow washout enhancement pattern, 2/12 a rapid washout pattern, 2/12 progressive enhancement, and 1/12 persistent enhancement. Imaging findings were suggestive of hemorrhage (50%), necrosis (25%), or cystic change (50%) within the tumors. Enlarged vessels were detected in 5/12 cases. One tumor extended into the renal sinus. No metastases were found on the preoperative MR imaging.

Conclusion

Although MRI appearances of renal EAML were various, some MRI characteristics may contribute to suggest the possibility of renal EAML.

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Authors and Affiliations

  1. Department of Radiology, Chinese PLA General Hospital, Fuxing Road 28, Box 100853, Beijing, China

    Yan Zhong, Yanguang Shen, Jingjing Pan, Yingwei Wang, Lu Ma, Huiyi Ye & Haiyi Wang

  2. Department of Pathology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, China

    Yunxia An & Aitao Guo

Authors
  1. Yan Zhong
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  2. Yanguang Shen
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  3. Jingjing Pan
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  4. Yingwei Wang
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  5. Yunxia An
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  6. Aitao Guo
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  7. Lu Ma
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  8. Huiyi Ye
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  9. Haiyi Wang
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Correspondence to Huiyi Ye or Haiyi Wang.

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The authors declare that they have no conflict of interest.

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This article does not contain any studies with human participants performed by any of the authors. Each author has participated sufficiently in any submission to take public responsibility for its content. Institutional Review Board approval was obtained and written informed consent was waived by the Institutional Review Board.

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Zhong, Y., Shen, Y., Pan, J. et al. Renal epithelioid angiomyolipoma: MRI findings. Radiol med 122, 814–821 (2017). https://doi.org/10.1007/s11547-017-0788-9

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