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The Effect of Polar Lipids on Tear Film Dynamics

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Abstract

In this paper, we present a mathematical model describing the effect of polar lipids, excreted by glands in the eyelid and present on the surface of the tear film, on the evolution of a pre-corneal tear film. We aim to explain the interesting experimentally observed phenomenon that the tear film continues to move upward even after the upper eyelid has become stationary. The polar lipid is an insoluble surface species that locally alters the surface tension of the tear film. In the lubrication limit, the model reduces to two coupled non-linear partial differential equations for the film thickness and the concentration of lipid. We solve the system numerically and observe that increasing the concentration of the lipid increases the flow of liquid up the eye. We further exploit the size of the parameters in the problem to explain the initial evolution of the system.

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Authors and Affiliations

  1. Mathematical Institute, University of Oxford, 24-29 St Giles’, Oxford, OX1 3LB, UK

    E. Aydemir & C. J. W. Breward

  2. Mathematics Department, Duke University, Box 90320, Durham, NC, 27708-0320, USA

    T. P. Witelski

Authors
  1. E. Aydemir
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  2. C. J. W. Breward
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  3. T. P. Witelski
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Correspondence to C. J. W. Breward.

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Aydemir, E., Breward, C.J.W. & Witelski, T.P. The Effect of Polar Lipids on Tear Film Dynamics. Bull Math Biol 73, 1171–1201 (2011). https://doi.org/10.1007/s11538-010-9555-y

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  • DOI: https://doi.org/10.1007/s11538-010-9555-y

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