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Tufted hair folliculitis in a woman treated with trastuzumab

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Abstract

Chemotherapeutic agents targeting the human epidermal receptor (HER) family are being used with increasing frequency for a variety of solid tumors. Cutaneous side effects are commonly reported with HER inhibitors, especially those agents that inhibit epidermal growth factor receptor (EGFR) or HER1. However, inhibitors of HER2 are not associated with specific skin toxicity. We present a case of tufted hair folliculitis, an inflammatory scalp condition causing scaling and pruritus, in a woman being treated with trastuzumab, a selective HER2 inhibitor. This finding has not previously been reported as a side effect of trastuzumab therapy.

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Conflict of interest statement

The author(s) has/have received or will receive benefits for personal or professional use from a commercial party related directly or indirectly to the subject of this manuscript.

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Authors and Affiliations

  1. Division of Dermatology, Washington University School of Medicine, 660 S. Euclid, Campus Box 8123, St. Louis, MO, 63110, USA

    Ilana S. Rosman & Milan J. Anadkat

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  1. Ilana S. Rosman
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  2. Milan J. Anadkat
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Correspondence to Milan J. Anadkat.

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Rosman, I.S., Anadkat, M.J. Tufted hair folliculitis in a woman treated with trastuzumab. Targ Oncol 5, 295–296 (2010). https://doi.org/10.1007/s11523-010-0162-5

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  • DOI: https://doi.org/10.1007/s11523-010-0162-5

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