Abstract
The speckle effects caused by the coherence of the laser light sources have restricted the performances of angular surface plasmon resonance (SPR) imaging sensors, which are widely used due to their wide linear rage, high refractive index (RI) resolution, and simple structure. In this work, we experimentally studied the influence of two common despeckle methods (laser with a rotating diffuser and an incoherent light-emitting diodes (LED) light source) on the RI resolution of an angular SPR imaging sensor. We found that the LED light source with a band-pass filter could not only eliminate the speckle effect completely but also provide better RI resolution than the other despeckle method. This low-cost speckle-free method has the potential to promote the development and the industrialization of angular SPR imaging sensors.
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References
Homola J, Yee SS, Gauglitz G (1999) Surface plasmon resonance sensors: review. Sensors Acutators B-Chem 54:3–15
Homola J, Piliarik M (2006) In: Homola J (ed) Surface plasmon resonance based sensors. Springer, Berlin
Homola J (2008) Surface plasmon resonance sensors for detection of chemical and biological species. Chem Rev 108:462–493
Schasfoort RBM, Tudos AJ (Eds.) (2008) Handbook of surface plasmon resonance. Royal Society of Chemistry
Piliarik M, Homola J (2008) Self-referencing SPR imaging for most demanding high-throughput screening applications. Sens Acutators B-Chem 134:353–355
Ng SP, Wu CML, Wu SY, Ho HP (2011) White-light spectral interferometry for surface plasmon resonance sensing applications. Opt Express 19(5):4521–4527
Liu L, He YH, Zhang Y, Ma SH, Ma H, Guo JH (2008) Parallel scan spectral surface plasmon resonance imaging. Appl Opt 47(30):5616–5621
Liu L, Chen XL, Liu ZY, Ma SH, Du C, He YH, Guo JH (2012) Polarization interference interrogation of angular surface plasmon resonance sensors with wide metal film thickness tolerance. Sens Acutators B-Chem 173:218–224
Lokate MC, Beusink JB, Besselink GAJ, Pruijn GJM, Schasfoort RBM (2007) Biomolecular interaction monitoring of autoantibodies by scanning surface plasmon resonance microarray imaging. J Am Chem Soc 129:14013–14018
O’Brien MJ II, Perez-Luna VH, Brueck SRJ, Lopez GP (2001) A surface plasmon resonance array biosensor based on spectroscopic imaging. Biosens Bioelectron 16:97–108
Chinowsky TM, Quinn JG, Bartholomew DU, Kaiser R, Elkind JL (2003) Performance of the Spreeta 2000 integrated surface plasmon resonance affinity sensor. Sens Acutators B-Chem 91:266–274
Yuk JS, Jung SH, Jung JW, Hong DG, Han JA, Kim YM, Ha KS (2004) Analysis of protein interactions on protein arrays by a wavelength interrogation-based surface plasmon resonance biosensor. Proteomics 4:3468–3476
Liu L, Ma SH, Ji YH, Chong XY, Liu ZY, He YH, Guo JH (2011) A two-dimensional polarization interferometry based parallel scan angular surface plasmon resonance biosensor. Rev Sci Instrum 82:023109
Somekh MG, Stabler G, Liu S, Zhang J, See CW (2009) Wide-field high-resolution surface-plasmon interference microscopy. Opt Lett 34(20):3110–3112
Thariani R, Yager P (2008) Novel, high-quality surface plasmon resonance microscopy. Sens Acutators B-Chem 130:765–770
Chinowsky TM, Grow MS, Johnston KS, Nelson K, Edwards T, Fu E, Yager P (2007) Compact, high performance surface plasmon resonance imaging system. Biosens Bioelectron 22:2208–2215
Vander R, Lipson SG (2009) High-resolution surface-plasmon resonance real-time imaging. Opt Lett 34(1):37–39
Liu ZY, Peng Q, Shi H, Sun SQ, Guo J, Wang XX, Liu L, Ji YH, Guo JH, Ma H, He YH (2013) MgF2-Au-MgF2-polydopamine based surface plasmon resonance sensor and its application in biomedical systems. Anal Methods 5:6306–6311
Shi H, Liu ZY, Wang XX, Guo J, Liu L, Luo L, Guo JH, Ma H, Sun SQ, He YH (2013) A symmetrical optical waveguide based surface plasmon resonance biosensing system. Sens Acutators B-Chem 185:91–96
Raether H (1998) Surface plasmons on smooth and rough surfaces and on gratings. Springer.
Piliarik M, Homola J (2009) Surface plasmon resonance (SPR) sensors: approaching their limits? Opt Express 17(19):16506–16517
Nenninger GG, Piliarik M, Homola J (2002) Data analysis for optical sensors based on spectroscopy of surface plasmons. Meas Sci Technol 13:2038–2046
Acknowledgments
This research was made possible with the financial support from NSFC China (61308119, 61361160416, 61275188, 61378089, and 81171375), the 863 project, China, Shenzhen International cooperation project, and the Technology Development Program of Shenzhen City.
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Liu, L., Guo, J., He, Y. et al. Study on the Despeckle Methods in Angular Surface Plasmon Resonance Imaging Sensors. Plasmonics 10, 729–737 (2015). https://doi.org/10.1007/s11468-014-9859-0
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DOI: https://doi.org/10.1007/s11468-014-9859-0