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Peroxidase-like properties of Ruthenium nanoframes

  • Article
  • Materials Science
  • Published:
Science Bulletin

Abstract

This work reports the inherent peroxidase-like properties of Ruthenium (Ru) nanoframes. After templating with Palladium (Pd) seeds, Ru nanoframes with an octahedral shape, average edge length of 6.2 nm, and thickness of 1.8 nm were synthesized in high purity (>95 %) and good uniformity. Using the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by H2O2 as a model catalytic reaction, the Ru frames were demonstrated to be approximately three times more active than natural peroxidases in catalyzing the formation of colored products. As compared to their natural counterparts, Ru frames have a stronger binding affinity to TMB as well as a weaker binding affinity to hydrogen peroxide during the catalysis. The Ru frames as peroxidase mimics proved to be chemically and thermally stable. This work represents the first demonstration of Ru nanostructure-based peroxidase mimics and is therefore expected to inspire future research on bio-applications of Ru nanomaterials.

摘要

本研究报道了钌纳米框架的过氧化物酶属性。选用钯纳米晶种为模板,可以制备得到具有八面体形貌的钌纳米框架,其平均边长为6.2纳米,厚度为1.8纳米,产物产率高(>95 %)并且形貌均匀。以过氧化氢氧化3,3′,5,5′-四甲基联苯胺分子(TMB)反应为催化模型,钌纳米框架的过氧化物酶活性比天然过氧化物酶高出接近3倍。和天然过氧化物酶相比,钌纳米框架在催化反应的过程中对3,3′,5,5′-四甲基联苯胺的结合力较强,但是对过氧化氢的结合力较弱。同时,钌纳米框架在催化反应中展示出较好的化学和热力学稳定性能。本研究首次提出了一种基于钌纳米晶的过氧化物模拟酶, 为钌纳米结构在生物应用方向的发展提供新的思路和前景。

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Acknowledgments

This work was partially supported by startup funds from Michigan Technological University, and the Michigan Translational Research & Commercialization Fund (MTRAC), Grant Case-48161 of the 21st Century Jobs Trust Fund received through the Michigan Strategic Fund from the State of Michigan. The MTRAC program is funded by the Michigan Strategic Fund with program oversight by the Michigan Economic Development Corporation.

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Authors and Affiliations

  1. Department of Chemistry, Michigan Technological University, Houghton, MI, 49931, USA

    Haihang Ye, Jacob Mohar & Xiaohu Xia

  2. Department of Materials Science and Engineering, University of Texas at Dallas, Richardson, TX, 75080, USA

    Qingxiao Wang, Massimo Catalano & Moon J. Kim

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  1. Haihang Ye
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  2. Jacob Mohar
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  3. Qingxiao Wang
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Correspondence to Xiaohu Xia.

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Ye, H., Mohar, J., Wang, Q. et al. Peroxidase-like properties of Ruthenium nanoframes. Sci. Bull. 61, 1739–1745 (2016). https://doi.org/10.1007/s11434-016-1193-9

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  • DOI: https://doi.org/10.1007/s11434-016-1193-9

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