Article PDF
Avoid common mistakes on your manuscript.
References
Cong, L., Ran, F.A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P.D., Wu, X., Jiang, W., Marraffini, L.A., and Zhang, F. (2013). Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819–823.
Cyranoski, D. (2015). Ethics of embryo editing divides scientists. Nature 519, 272.
Cyranoski, D., and Reardon, S. (2015). Embryo editing sparks epic debate. Nature 520, 593–594.
Deng, L., Ren, R., Wu, J., Suzuki, K., Izpisua Belmote, J.C., and Liu, G.H. (2015). CRISPR/Cas9 and TALE: beyond cut and paste. Protein Cell 6, 157–159.
Ding, Z., Sui, L., Ren, R., Liu, Y., Xu, X., Fu, L., Bai, R., Yuan, T., Hao, Y., Zhang, W., Pan, H., Liu, W., Yu, H., Estaban, C.R., Yu, X., Yang, Z., Li, J., Wang, X., Izpisua Belmonte, J.C., Liu, G.H., Yi, F., Qu, J. (2015). A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells. Protein Cell 6, 386–389.
Gao, F., Shen, X.Z., Jiang, F., Wu, Y., Han, C. (2016). DNA-guided genome editing using the Natronobacterium gregoryi Argonaute. Nat Biotechnol 34, 768–73.
Hai, T., Teng, F., Guo, R., Li, W., and Zhou, Q. (2014). One-step generation of knockout pigs by zygote injection of CRISPR/Cas system. Cell Res 24, 372–375.
Liang, P., Xu, Y., Zhang, X., Ding, C., Huang, R., Zhang, Z., Lv, J., Xie, X., Chen, Y., Li, Y., Sun, Y., Bai, Y., Songyang, Z., Ma, W., Zhou, C., Huang, J. (2015). CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes. Protein Cell 6, 363–372.
Liu, G.H., Qu, J., Suzuki, K., Nivet, E., Li, M., Montserrat, N., Yi, F., Xu, X., Ruiz, S., Zhang, W., Wagner, U., Kim, A., Ren, B., Li, Y., Goebl, A., Kim, J, Soligalla, R.D., Dubova, I., Thompson, J., Yates, J., Esteban, C.R., Sancho-Martinez, I., Izpisua Belmonte, J.C. (2012). Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature 491, 603–607.
Liu, G.H., Suzuki, K., Li, M., Qu, J., Montserrat, N., Tarantino, C., Gu, Y., Yi, F., Xu, X., Zhang, W., Ruiz S., Plongthongkum, N., Zhang, K., Masuda, S., Nivet, E., Tsunekawa, Y., Soligalla, R.D., Goebl, A., Aizawa, E., Kim, N.Y., Kim, J., Dubova, I., Li, Y., Ren, R., Benner C., del Sol A., Bueren, J., Trujillo, J.P., Surralles, J., Cappelli, E., Dufour, C., Esteban, C.R., Izpisua Belmonte, J.C. (2014). Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Nat Commun 5, 4330.
Mali, P., Yang, L., Esvelt, K.M., Aach, J., Guell, M., DiCarlo, J.E., Norville, J.E., and Church, G.M. (2013). RNA-guided human genome engineering via Cas9. Science 339, 823–826.
Niu, Y., Shen, B., Cui, Y., Chen, Y., Wang, J., Wang, L., Kang, Y., Zhao, X., Si, W., Li, W., Xiang, A.P., Zhou, J., Guo, X., Bi, Y., Si, C., Hu, B., Dong, G., Wang, H., Zhou, Z., Li, T., Tan, T., Pu, X., Wang, F., Ji, S., Zhou, Q., Huang, X., Ji, W., Sha, J. (2014). Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. Cell 156, 836–843.
Pan, H., Zhang, W., and Liu, G.H. (2011). Find and replace: editing human genome in pluripotent stem cells. Protein Cell 2, 950–956.
Rong, Z., Zhu, S., Xu, Y., and Fu, X. (2014). Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template. Protein Cell 5, 258–260.
Shen, Z., and Ou, G. (2014). CRISPR-Cas9 knockout screening for functional genomics. Sci China Life Sci 57, 733–734.
Zhang, K., Liu, G.H., Yi, F., Montserrat, N., Hishida, T., Esteban, C.R., and Izpisua Belmonte, J.C. (2014). Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors. Protein Cell 5, 48–58.
Zhang, L., and Zhou, Q. (2014). CRISPR/Cas technology: a revolutionary approach for genome engineering. Sci China Life Sci 57, 639–640.
Zhang, X. (2015). Urgency to rein in the gene-editing technology. Protein Cell 6, 313.
Zhou, Y., Zhu, S., Cai, C., Yuan, P., Li, C., Huang, Y., and Wei, W. (2014). High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells. Nature 509, 487–491.
Author information
Authors and Affiliations
Corresponding authors
Additional information
This article is published with open access at link.springer.com
Rights and permissions
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0), which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
About this article
Cite this article
Zhang, X., Wang, S. From the first human gene-editing to the birth of three-parent baby. Sci. China Life Sci. 59, 1341–1342 (2016). https://doi.org/10.1007/s11427-016-0358-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11427-016-0358-3