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Antiviral polysaccharides isolated from Hong Kong brown seaweed Hydroclathrus clathratus

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Abstract

Two relatively pure polysaccharides H3-a1 and H3-b1 had been isolated from the brown seaweed Hydroclathrus clathratus. They were characterized by HPLC, ultraviolet scanning, gas chromatography, infrared spectroscopy and elemental analysis, and shown to be two different sulfated polysaccharides with different monosaccharide content, but both with high relative molecular mass. They contained some proteins and uronic acid respectively. The sulfate content and bioactivity of these polysaccharides varied during purification. The fractions derived from the hot water extract also exhibited low anticoagulant effect. This is the first time that the antiherpetic and anticoagulant activities were evaluated for the polysaccharides from the Hong Kong brown seaweed Hydroclathrus clathratus.

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Authors and Affiliations

  1. Medical College, Jinan University, Guangzhou, 510632, China

    Wang Hui

  2. Department of Biology, the Chinese University of Hong Kong, Shatin N.T., Hong Kong SAR, China

    Ooi Engchoon Vincent & Ang Put O. Jr.

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  1. Wang Hui
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  2. Ooi Engchoon Vincent
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  3. Ang Put O. Jr.
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Correspondence to Ang Put O. Jr..

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Supported by the Research Grants Council of the Hong Kong Special Administrative Region, China (Project No. CUHK4367/01M) and a Direct Grant from the Chinese University of Hong Kong

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Wang, H., Ooi, E.V. & Ang, P.O. Antiviral polysaccharides isolated from Hong Kong brown seaweed Hydroclathrus clathratus . SCI CHINA SER C 50, 611–618 (2007). https://doi.org/10.1007/s11427-007-0086-1

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  • DOI: https://doi.org/10.1007/s11427-007-0086-1

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