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Amberlyst-15® in PEG: A novel catalytic system for the facile and efficient one-pot synthesis of benzothiazolo-[2,3-b]-quinazolinone derivatives

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Abstract

A simple and convenient approach for the synthesis of tetraheterocyclic benzothiazolo-[2,3-b]-quinazolin-1-ones has been developed utilizing the MCR methodology, which involves the condensation of 2-aminobenzothiazole, cyclic β-diketones and various aldehydes using Amberlyst-15® in PEG 400 as an environmentally benign and reusable catalyst system. Environmental benignity, recyclability, cost-effectiveness, easy workup and excellent yields are the major attributes of this one-pot procedure.

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Authors and Affiliations

  1. Green Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi, 110007, India

    Kidwai Mazaahir, Chauhan Ritika & Bhatnagar Divya

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  1. Kidwai Mazaahir
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  2. Chauhan Ritika
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  3. Bhatnagar Divya
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Correspondence to Kidwai Mazaahir.

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Presently working as Vice-Chancellor, Jiwaji University, Gwalior (M. P.), India (On Deputation from Department of Chemistry, University of Delhi, Delhi-110007, India)

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Mazaahir, K., Ritika, C. & Divya, B. Amberlyst-15® in PEG: A novel catalytic system for the facile and efficient one-pot synthesis of benzothiazolo-[2,3-b]-quinazolinone derivatives. Sci. China Chem. 55, 2154–2160 (2012). https://doi.org/10.1007/s11426-012-4665-z

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  • DOI: https://doi.org/10.1007/s11426-012-4665-z

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