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A new prenylated dihydrochalcone from the leaves of Artocarpus lowii

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Abstract

A new prenylated dihydrochalcone, 2′,4′-dihydroxy-4-methoxy-3′-prenyldihydrochalcone (1), along with two known compounds, 2′,4′,4-trihydroxy-3′-prenylchalcone (2) and 2′,4-dihydroxy-3′,4′-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1–3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1–3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.

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Acknowledgments

This research was supported by grants from FELDA and UTM. One of the authors (SJ) would like to thank UTM for the scholarship.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, UTM Skudai, 81310, Johor Bahru, Johor, Malaysia

    Shajarahtunnur Jamil & Hasnah Mohd Sirat

  2. Department of Pharmacy, Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia

    Ibrahim Jantan

  3. Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba, 263-8522, Japan

    Norio Aimi & Mariko Kitajima

Authors
  1. Shajarahtunnur Jamil
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  2. Hasnah Mohd Sirat
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  3. Ibrahim Jantan
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  4. Norio Aimi
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  5. Mariko Kitajima
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Correspondence to Shajarahtunnur Jamil.

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Jamil, S., Sirat, H.M., Jantan, I. et al. A new prenylated dihydrochalcone from the leaves of Artocarpus lowii . J Nat Med 62, 321–324 (2008). https://doi.org/10.1007/s11418-008-0226-3

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  • DOI: https://doi.org/10.1007/s11418-008-0226-3

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