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Organizational Facilitators and Barriers to Medication for Opioid Use Disorder Capacity Expansion and Use

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Abstract

Medication for opioid use disorder (MOUD) is a key strategy for addressing the opioid use disorder crisis, yet gaps in MOUD provision impede this strategy’s benefits. The research reported here sought to understand what distinguishes low- and high-performing organizations in building and using capacity to provide MOUD. As part of a mixed methods MOUD implementation trial, semi-structured telephone interviews were conducted with personnel from low- and high-performing MOUD-providing organizations. Seventeen individuals from 17 organizations were interviewed. Findings demonstrate the importance of individual, organization, and community-level factors in supporting the building and use of MOUD capacity. Low- and high-performing organizations showed different patterns of facilitators and barriers during the implementation process. The key difference between low- and high-performing organizations was the level of organizational functioning. A better understanding of an organization’s assets and deficits at the individual, organizational, and community levels would allow decision-makers to tailor their approaches to MOUD implementation.

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References

  1. Xu J, Murphy S, Kochanek K, et al. Mortality in the United States, 2018. Hyattsville: National Center for Health Statistics (NCHS), 2020. Available at https://www.cdc.gov/nchs/data/databriefs/db355-h.pdf. Accessed 3 March 2020.

  2. Florence CS, Zhou C, Luo F, et al. The economic burden of prescription opioid overdose, abuse, and dependence in the United States, 2013. Medical Care. 2016;54(10):901-906.

    PubMed  PubMed Central  Google Scholar 

  3. Radel L, Baldwin M, Crouse G, et al. Substance use, the opioid epidemic, and the child welfare system: key findings from a mixed methods study. U.S. Department of Health and Human Services, Office of the Assistant Secretary for Planning and Evaluation, 2018. Available at https://aspe.hhs.gov/system/files/pdf/258836/SubstanceUseChildWelfareOverview.pdf. Accessed 3 March 2020.

  4. Lynch S, Sherman L, Snyder SM, et al. Trends in infants reported to child welfare with neonatal abstinence syndrome (NAS). Children and Youth Services Review. 2018;86:135-141.

    Google Scholar 

  5. Volkow ND, Wargo EM. Overdose prevention through medical treatment of opioid use disorders. Annals of Internal Medicine. 2018;169(3):190-192.

    PubMed  Google Scholar 

  6. McCance-Katz EF. SAMHSA/HHS: An update on the opioid crisis. Rockville: Substance Abuse and Mental Health Services Administration, 2018. Available at https://www.samhsa.gov/sites/default/files/aatod_2018_final.pdf. Accessed 3 March 2020.

  7. Connery HS. Medication-assisted treatment of opioid use disorder: review of the evidence and future directions. Harvard Review of Psychiatry. 2015;23(2):63-75.

    PubMed  Google Scholar 

  8. Krupitsky E, Nunes EV, Ling W, et al. Injectable extended-release naltrexone for opioid dependence: a double-blind, placebo-controlled, multicentre randomised trial. Lancet (London, England). 2011;377(9776):1506-1513.

    CAS  Google Scholar 

  9. Hser YI, Evans E, Huang D, et al. Long-term outcomes after randomization to buprenorphine/naloxone versus methadone in a multi-site trial. Addiction (Abingdon, England). 2016;111(4):695-705.

    Google Scholar 

  10. Lee JD, Friedmann PD, Kinlock TW, et al. Extended-release naltrexone to prevent opioid relapse in criminal justice offenders. New England Journal of Medicine. 2016;374(13):1232-1242.

    CAS  PubMed  Google Scholar 

  11. Mozurkewich EL, Rayburn WF. Buprenorphine and methadone for opioid addiction during pregnancy. Obstetrics and Gynecology Clinics of North America. 2014;41(2):241-253.

    PubMed  Google Scholar 

  12. Larochelle MR, Bernson D, Land T, et al. Medication for opioid use disorder after nonfatal opioid overdose and association with mortality: a cohort study. Annals of Internal Medicine. 2018;169(3):137-145.

    PubMed  PubMed Central  Google Scholar 

  13. Ma J, Bao YP, Wang RJ, et al. Effects of medication-assisted treatment on mortality among opioids users: a systematic review and meta-analysis. Molecular Psychiatry. 2019;24(12):1868-1883.

    PubMed  Google Scholar 

  14. American Society of Addiction Medicine (ASAM). The ASAM National Practice Guideline for the Use of Medications in the Treatment of Addiction involving Opioid Use. Chevy Chase: American Society of Addiction Medicine, 2015.

    Google Scholar 

  15. World Health Organization. Essential Medicines: WHO Model List (revised March 2005). Geneva: World Health Organization, 2003.

    Google Scholar 

  16. Volkow ND, Frieden TR, Hyde PS, et al. Medication-assisted therapies--tackling the opioid-overdose epidemic. New England Journal of Medicine. 2014;370(22):2063-2066.

    PubMed  Google Scholar 

  17. Jones CM, Campopiano M, Baldwin G, et al. National and state treatment need and capacity for opioid agonist medication-assisted treatment. American Journal of Public Health. 2015;105(8):e55-63.

    PubMed  PubMed Central  Google Scholar 

  18. Substance Abuse and Mental Health Services Administration (SAMHSA). National Survey of Substance Abuse Treatment Services (N-SSATS) 2016: Data on Substance Abuse Treatment Facilities. Rockville: Substance Abuse and Mental Health Services Administration, 2017.

  19. Jones CM, McCance-Katz EF. Characteristics and prescribing practices of clinicians recently waivered to prescribe buprenorphine for the treatment of opioid use disorder. Addiction (Abingdon, England). 2019;114(3):471-482.

    Google Scholar 

  20. Substance Abuse and Mental Health Services Administration (SAMHSA). Drug Addiction Treatment Act of 2000 (DATA 2000). Public Law No. 106–310, Title XXXV-Waiver authority for physicians who dispense or prescribe certain narcotic drugs for maintenance treatment or detoxification treatment. Rockville: Substance Abuse and Mental Health Services Administration, 2000.

    Google Scholar 

  21. Tiberg F, Johnsson M, Harwigsson I, Inventors. U.S. Patent Application No. 15/520,946. 2018.

  22. Grol R, Grimshaw J. From best evidence to best practice: effective implementation of change in patients’ care. Lancet (London, England). 2003;362(9391):1225-1230.

    Google Scholar 

  23. Brownson RC, Colditz GA, Proctor EK, eds. Dissemination and Implementation Research in Health: Translating Science to Practice. Second ed. New York: Oxford University Press, 2017.

    Google Scholar 

  24. Socias ME, Volkow N, Wood E. Adopting the ‘cascade of care’ framework: an opportunity to close the implementation gap in addiction care? Addiction (Abingdon, England). 2016;111(12):2079-2081.

    Google Scholar 

  25. Knudsen HK, Roman PM. The transition to medication adoption in publicly funded substance use disorder treatment programs: organizational structure, culture, and resources. Journal of Studies on Alcohol and Drugs. 2014;75(3):476-485.

    PubMed  PubMed Central  Google Scholar 

  26. U.S. Government Accountability Office. Opioid Crisis: Status of Public Health Emergency Authorities. By Mary Denigan-Macauley, Acting Director, Health Care. Washington, DC: U.S. Government Accountability Office, September 26, 2018.

  27. Aletraris L, Edmond MB, Paino M, et al. Counselor training and attitudes toward pharmacotherapies for opioid use disorder. Substance Abuse : official publication of the Association for Medical Education and Research in Substance Abuse. 2016;37(1):47-53.

    Google Scholar 

  28. Uebelacker LA, Bailey G, Herman D, et al. Patients’ beliefs about medications are associated with stated preference for methadone, buprenorphine, naltrexone, or no medication-assisted therapy following inpatient opioid detoxification. Journal of Substance Abuse Treatment. 2016;66:48-53.

    PubMed  PubMed Central  Google Scholar 

  29. Hutchinson E, Catlin M, Andrilla CHA, et al. Barriers to primary care physicians prescribing buprenorphine. The Annals of Family Medicine. 2014;12(2):128-133.

    PubMed  Google Scholar 

  30. Molfenter T. The pressing shortage of buprenorphine prescribers and the pending role of telemedicine. Addiction Science & Clinical Practice. 2015;10(Suppl 1):A40.

    Google Scholar 

  31. Andrilla CHA, Coulthard C, Larson EH. Barriers rural physicians face prescribing buprenorphine for opioid use disorder. Annals of Family Medicine. 2017;15(4):359-362.

    PubMed  PubMed Central  Google Scholar 

  32. Alanis-Hirsch K, Croff R, Ford JH, 2nd, et al. Extended-release naltrexone: a qualitative analysis of barriers to routine use. Journal of Substance Abuse Treatment. 2016;62:68-73.

    PubMed  Google Scholar 

  33. Molfenter T, Sherbeck C, Starr S, et al. Payer policy behavior towards opioid pharmacotherapy treatment in Ohio. Journal of Addiction Medicine. 2018;12(2):85-91.

    PubMed  Google Scholar 

  34. Molfenter T, Knudsen HK, Brown R, et al. Test of a workforce development intervention to expand opioid use disorder treatment pharmacotherapy prescribers: protocol for a cluster randomized trial. Implementation Science. 2017;12(1):135.

    PubMed  Google Scholar 

  35. Proctor E, Silmere H, Raghavan R, et al. Outcomes for Implementation Research: Conceptual Distinctions, Measurement Challenges, and Research Agenda. Administration and Policy in Mental Health. 2011;38(2):65-76.

    PubMed  Google Scholar 

  36. Scott SD, Plotnikoff RC, Karunamuni N, et al. Factors influencing the adoption of an innovation: an examination of the uptake of the Canadian Heart Health Kit (HHK). Implementation Science. 2008;3:41.

    PubMed  Google Scholar 

  37. Schuman-Olivier Z, Connery H, Griffin ML, et al. Clinician beliefs and attitudes about buprenorphine/naloxone diversion. The American Journal on Addictions / American Academy of Psychiatrists in Alcoholism and Addictions. 2013;22(6):574-580.

    PubMed Central  Google Scholar 

  38. Thomas C, Reif S, Haq S, et al. Use of buprenorphine for addiction treatment: perspectives of addiction specialists and general psychiatrists. Psychiatric Services. 2008;59(8):909-916.

    PubMed  Google Scholar 

  39. Fitzgerald J, McCarty D. Understanding attitudes toward use of medication in substance abuse treatment: a multilevel approach. Psychological Services. 2009;6(1):74.

    PubMed  PubMed Central  Google Scholar 

  40. Aarons GA, Green AE, Trott E, et al. The roles of system and organizational leadership in system-wide evidence-based intervention sustainment: a mixed-method study. Administration and Policy in Mental Health. 2016;43(6):991-1008.

    PubMed  PubMed Central  Google Scholar 

  41. Stetler CB, Ritchie JA, Rycroft-Malone J, et al. Leadership for evidence-based practice: strategic and functional behaviors for institutionalizing EBP. Worldviews on Evidence-Based Nursing. 2014;11(4):219-226.

    PubMed  Google Scholar 

  42. Gordon AJ, Kavanagh G, Krumm M, et al. Facilitators and barriers in implementing buprenorphine in the Veterans Health Administration. Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors. 2011;25(2):215-224.

    Google Scholar 

  43. Proctor EK. Leverage points for the implementation of evidence-based practice. Brief Treatment and Crisis Intervention. 2004;4(3):227.

    Google Scholar 

  44. Huhn AS, Dunn KE. Why aren’t physicians prescribing more buprenorphine? Journal of Substance Abuse Treatment. 2017;78:1-7.

    PubMed  PubMed Central  Google Scholar 

  45. Wen H, Hockenberry JM, Borders TF, et al. Impact of Medicaid expansion on Medicaid-covered utilization of buprenorphine for opioid use disorder treatment. Medical Care. 2017;55(4):336-341.

    PubMed  Google Scholar 

  46. Stein BD, Sorbero M, Dick AW, et al. Physician capacity to treat opioid use disorder with buprenorphine-assisted treatment. JAMA. 2016;316(11):1211-1212.

    PubMed  PubMed Central  Google Scholar 

  47. Gustafson DH, Sainfort F, Eichler M, et al. Developing and testing a model to predict outcomes of organizational change. Health Services Research. 2003;38(2):751-776.

    PubMed  PubMed Central  Google Scholar 

  48. Weiner BJ, Lewis MA, Linnan LA. Using organization theory to understand the determinants of effective implementation of worksite health promotion programs. Health Education Research. 2009;24(2):292-305.

    PubMed  Google Scholar 

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Acknowledgments

The study team gratefully acknowledges the contributions of those who participated in interviews. Editorial assistance from Maureen Fitzpatrick and Judith Ganch was also greatly appreciated.

Funding

This study was supported by a grant from the National Institute on Drug Abuse (NIDA Grant R01DA030431; PI: Molfenter).

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Correspondence to Nora Jacobson PhD.

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All key informants provided verbal informed consent, and all study procedures were reviewed and approved by the University of Wisconsin’s Institutional Review Board.

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The authors declare that they have no conflicts of interest.

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NIDA has played no role in the study design or preparation of this manuscript. The authors are solely responsible for the content of this manuscript, which does not represent the official views of the National Institutes of Health or NIDA.

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Jacobson, N., Horst, J., Wilcox-Warren, L. et al. Organizational Facilitators and Barriers to Medication for Opioid Use Disorder Capacity Expansion and Use. J Behav Health Serv Res 47, 439–448 (2020). https://doi.org/10.1007/s11414-020-09706-4

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