Abstract
Based on nationally representative samples from US, we aimed to assess the associations of vitamins with hearing loss, vision disorder and sleep problem. A total of 25,312, 8425 and 24,234 participants were included in this study to investigate the relationship of vitamins with hearing loss, vision disorder and sleep problem from National Health and Nutrition Examination Survey, respectively. Vitamins including niacin, folic acid, vitamin B6, A, C, E and carotenoids were considered in our study. Logistic regression models were used to assess the associations between all included dietary vitamin intake concentrations and the prevalence of specific outcomes. Increased lycopene (odds ratio [OR]: 0.904, 95% confidence interval [CI]: 0.829–0.985) intake was associated with a deceased prevalence of hearing loss. Higher dietary intake of folic acid (OR: 0.637, 95% CI: 0.443–0.904), vitamin B6 (0.667, 0.465–0.947), alpha-carotene (0.695, 0.494–0.968), beta-carotene (0.703, 0.505–0.969) and lutein + zeaxanthin (0.640, 0.455–0.892) were associated with a decreased prevalence of vision disorder. The inversely associations of sleeping problem with niacin (OR: 0.902, 95% CI: 0.826–0.985), folic acid (0.882, 0.811–0.959), vitamin B6 (0.892, 0.818–0.973), vitamin C (0.908, 0.835–0.987), vitamin E (0.885, 0.813–0.963) and lycopene (0.919, 0.845–0.998) were also observed. Our findings provide evidence that increased specific vitamin intake is associated with decreased prevalence of hearing loss, vision disorder and sleep problem.
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Data availability
All data generated or analyzed during our study are extracted from the NHANES (https://wwwn.cdc.gov/Nchs/Nhanes/).
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We thank the study group of the National Health and Nutrition Examination Survey.
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The study was supported by the Fundamental Research Funds for the Central Universities (2021XXJS017), Health Commission of Hubei Province scientific research project (WJ2023M002), and National key research and development program of China (2022YFC2503203). The funder did not play any role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; nor in the preparation, review, or approval of the manuscript.
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ZMC wrote the manuscript and performed statistical analysis. ZMC, LLY and DMW conceived and designed the study, and interpreted data. WHC, DMW, LLY, WZL, HZZ, XZH critically revised the manuscript and approved the final version. ZMC, LLY and DMW are the guarantors of this work and, as such, had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
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Chen, Z., Yu, L., Li, W. et al. Association of vitamins with hearing loss, vision disorder and sleep problem in the US general population. Environ Sci Pollut Res 30, 53876–53886 (2023). https://doi.org/10.1007/s11356-023-26164-5
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DOI: https://doi.org/10.1007/s11356-023-26164-5