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Fabrication and characterization of β-cypermethrin-loaded PLA microcapsules prepared by emulsion-solvent evaporation: loading and release properties

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Abstract

Microcapsulses can be designed to effectively encapsulate, protect, and control the release of pesticides. In this study, emulsion-solvent evaporation method was used to fabricate microcapsules using dichloromethane as the solvent, polylactic acid (PLA) as the carrier materials, poly(vinyl alcohol) as the emulsifier, and β-cypermethrin as the entrapped pesticide. The effects of process parameters on the microcapsules characteristics (size, loading content, and encapsulation efficiency) were investigated. Also, the release behavior of the β-cypermethrin was measured experimentally and modeled mathematically. Kinetic analysis indicated that release mechanism of β-cypermethrin was compatible to Fickian diffusion. By optimizing the process parameters, β-cypermethrin-loaded microcapsules were successfully produced with spherical shape, smooth surface, high encapsulation efficiency (> 80%), and a range of pesticide contents. These parameters could be adjusted to achieve delivery systems with desirable release profiles. The results are beneficial to develop delivery systems for rational and effective usage of pesticides.

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Funding

We are grateful for financial support from Basic Research Project (Natural Science Foundation for Young Scholars) of Jiangsu Province, China (Grant No. BK20170489); Basic Research Project (Natural Science Foundation for Young Scientists) of Yangzhou, China (Grant No. YZ2016104); and Program of Practice and Innovation Training Projects for College Students in Jiangsu Province (Grant Nos. 201511117091X, 201711117053Y).

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Authors and Affiliations

  1. School of Horticulture and Plant Protection, Yangzhou University, Yangzhou, 225009, China

    Jianguo Feng, Guantian Yang & Shengwei Zhang

  2. School of Medicine, Yangzhou University, Yangzhou, China

    Qi Liu

  3. Department of Food Materials and Process Design Engineering, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran

    Seid Mahdi Jafari

  4. Department of Food Science, Unviersity of Massachusetts, Amherst, MA, 01004, USA

    David Julian McClements

Authors
  1. Jianguo Feng
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  2. Guantian Yang
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  3. Shengwei Zhang
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  4. Qi Liu
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  5. Seid Mahdi Jafari
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  6. David Julian McClements
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Corresponding authors

Correspondence to Jianguo Feng or Seid Mahdi Jafari.

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Responsible editor: Santiago V. Luis

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Feng, J., Yang, G., Zhang, S. et al. Fabrication and characterization of β-cypermethrin-loaded PLA microcapsules prepared by emulsion-solvent evaporation: loading and release properties. Environ Sci Pollut Res 25, 13525–13535 (2018). https://doi.org/10.1007/s11356-018-1557-6

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  • DOI: https://doi.org/10.1007/s11356-018-1557-6

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