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Epworth sleepiness scale scores and adverse pregnancy outcomes

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Abstract

Purpose

Snoring is associated with adverse pregnancy outcomes including gestational hypertensive disorders, gestational diabetes, and Cesarean deliveries. The purpose of this study was to assess whether excessive daytime sleepiness (EDS) assessed by Epworth Sleepiness Scale (ESS) increases the risk of these complications further.

Methods

Following institutional review board approval and informed consent, English-speaking women in the immediate postpartum period were systematically selected and recruited. Women answered a survey that included questions regarding symptoms of sleep-disordered breathing (SDB) using the multivariable apnea prediction index and excessive daytime sleepiness using ESS. Pregnancy and fetal outcomes were collected by review of medical records. Standard statistical analysis with multivariable logistic regression was performed. ESS was evaluated both as a continuous variable and with various cutoffs given that pregnant women are likely more sleepy at baseline than the general population.

Results

In patients who underwent planned Cesarean delivery, mean ESS was significantly higher than in those with uncomplicated vaginal delivery, even after adjusting for confounders (adjusted odds ratio (aOR), 1.08; 95 % CI, 1.01–1.15; p = 0.02). There was no significant association between EDS (defined as ESS of >10) and gestational diabetes or gestational hypertensive disorders in snorers or non snorers. However, a significant association with gestational diabetes was found in patients with an ESS of >16 compared to those with an ESS of ≤16, even after multiple adjustments (aOR, 6.82; 95 % CI, 1.19–39.27), but the number of subjects in an ESS of >16 category was small.

Conclusions

There is an increased association between women with higher ESS and planned Cesarean delivery. Severe EDS was associated with gestational diabetes in pregnant women in a small sample size. Future studies in larger samples need to confirm the association of severe EDS and gestational diabetes and elucidate potential mechanisms of the links with adverse outcomes.

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Acknowledgments

Ghada Bourjeily has received funding from Perkins Charitable Foundation. The foundation did not have a role in the study design, data analysis, or manuscript preparation

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Authors and Affiliations

  1. Department of Medicine, The Miriam Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA

    Ghada Bourjeily

  2. Internal Medicine Residency Program, Lebanese University, Beirut, Lebanon

    Rana El Sabbagh

  3. Radiology Residency Program, American University of Beirut, Beirut, Lebanon

    Peter Sawan

  4. Division of Research, Women and Infants Hospital of Rhode Island, Providence, RI, USA

    Christina Raker

  5. Pulmonary and Critical Care Fellowship Program, The Warren Alpert Medical School of Brown University, Providence, RI, USA

    Carren Wang

  6. The Miriam Hospital, Women’s Medicine Collaborative, Providence, RI, USA

    Beth Hott

  7. Department of Medicine, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA

    Mariam Louis

  8. Women’s Medicine Collaborative of Lifespan, The Miriam Hospital, 146 West River Street, Suite 11C, Providence, RI, 02904, USA

    Ghada Bourjeily

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  1. Ghada Bourjeily
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  2. Rana El Sabbagh
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Correspondence to Ghada Bourjeily.

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Bourjeily, G., El Sabbagh, R., Sawan, P. et al. Epworth sleepiness scale scores and adverse pregnancy outcomes. Sleep Breath 17, 1179–1186 (2013). https://doi.org/10.1007/s11325-013-0820-9

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  • DOI: https://doi.org/10.1007/s11325-013-0820-9

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