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Supine fluid redistribution: should we consider this as an important risk factor for obstructive sleep apnea?

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Abstract

Introduction

Obstructive sleep apnea (OSA) is a common medical disorder affecting at least 2 % of women and 4 % of men living in Western societies. Obesity, older age, male gender, alcohol and sedative use, smoking, craniofacial parameters, and volume overload are some of the risk factors for this disorder.

Discussion

OSA is a known risk factor complicating the course of arterial hypertension, heart failure, and chronic kidney disease. It is important to note that all of the aforementioned comorbid disorders are associated with volume overload. This explains why patients with OSA and comorbid disorders associated with fluid overload can benefit from treatment with diuretics and drugs modulating the renin–angiotensin–aldosterone system. Additionally, patients with heart failure and high sodium intake are at increased risk for OSA, further supporting the complex interrelationship.

Conclusions

Hemodialysis and renal transplantation can markedly improve the severity of OSA in patients with concomitant kidney disease. Finally, there is a potential of a vicious cycle between OSA and fluid overload disorders, whereby OSA can contribute to the pathogenesis of arterial hypertension, heart failure, and chronic kidney disease, which in turn will significantly contribute to the course OSA.

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References

  1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235

    Article  PubMed  CAS  Google Scholar 

  2. Anonymous (1999) Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The report of an American Academy of Sleep Medicine Task Force. Sleep 22:667–689

  3. Jaffe LM, Kjekshus J, Gottlieb SS (2012) Importance and management of chronic sleep apnoea in cardiology. Eur Heart J. PMID: 22427382. doi:10.1093/eurheartj/ehs046

  4. Mirrakhimov AE (2012) Obstructive sleep apnea and kidney disease: is there any direct link? Sleep Breath. PMID: 22170216 (in press)

  5. Pamidi S, Aronsohn RS, Tasali E (2010) Obstructive sleep apnea: role in the risk and severity of diabetes. Best Pract Res Clin Endocrinol Metab 24:703–715

    Article  PubMed  Google Scholar 

  6. Punjabi NM, Caffo BS, Goodwin JL, Gottlieb DJ, Newman AB, O'Connor GT et al (2009) Sleep-disordered breathing and mortality: a prospective cohort study. PLoS Med 6:e1000132

    Article  PubMed  Google Scholar 

  7. Oksenberg A, Silverberg DS, Arons E, Radwan H (1999) The sleep supine position has a major effect on optimal nasal continuous positive airway pressure: relationship with rapid eye movements and non-rapid eye movements sleep, body mass index, respiratory disturbance index, and age. Chest 116:1000–1006

    Article  PubMed  CAS  Google Scholar 

  8. Fischer MK, Martinez D, Cassol CM, Rahmeier L, Vieira LR (2012) Immediate and overnight recumbence-dependent changes of neck circumference: relationship with OSA severity in obese and nonobese subjects. Sleep Med 13:650–655

    Article  PubMed  Google Scholar 

  9. Raff H, Roarty TP (1988) Renin, ACTH, and aldosterone during acute hypercapnia and hypoxia in conscious rats. Am J Physiol 254:R431–435

    PubMed  CAS  Google Scholar 

  10. Fletcher EC, Bao G, Li R (1999) Renin activity and blood pressure in response to chronic episodic hypoxia. Hypertension 34:309–314

    Article  PubMed  CAS  Google Scholar 

  11. Fletcher EC, Orolinova N, Bader M (2002) Blood pressure response to chronic episodic hypoxia: the renin–angiotensin system. J Appl Physiol 92:627–633

    Article  PubMed  CAS  Google Scholar 

  12. Pratt-Ubunama MN, Nishizaka MK, Boedefeld RL, Cofield SS, Harding SM, Calhoun DA (2007) Plasma aldosterone is related to severity of obstructive sleep apnea in subjects with resistant hypertension. Chest 131:453–459

    Article  PubMed  CAS  Google Scholar 

  13. Di Murro A, Petramala L, Cotesta D, Zinnamosca L, Crescenzi E, Marinelli C, Saponara M, Letizia C (2010) Renin–angiotensin–aldosterone system in patients with sleep apnoea: prevalence of primary aldosteronism. J Renin Angiotensin Aldosterone Syst 11:165–172

    Article  PubMed  Google Scholar 

  14. Foster GE, Hanly PJ, Ahmed SB, Beaudin AE, Pialoux V, Poulin MJ (2010) Intermittent hypoxia increases arterial blood pressure in humans through a renin–angiotensin system-dependent mechanism. Hypertension 56:369–377

    Article  PubMed  CAS  Google Scholar 

  15. Pialoux V, Foster GE, Ahmed SB, Beaudin AE, Hanly PJ, Poulin MJ (2011) Losartan abolishes oxidative stress induced by intermittent hypoxia in humans. J Physiol 589:5529–5537

    PubMed  CAS  Google Scholar 

  16. Svatikova A, Olson LJ, Wolk R, Phillips BG, Adachi T, Schwartz GL, Somers VK (2009) Obstructive sleep apnea and aldosterone. Sleep 32:1589–1592

    PubMed  Google Scholar 

  17. Carlson JT, Hedner J, Elam M, Ejnell H, Sellgren J, Wallin BG (1993) Augmented resting sympathetic activity in awake patients with obstructive sleep apnea. Chest 103:1763–1768

    Article  PubMed  CAS  Google Scholar 

  18. Shepard JW Jr, Pevernagie DA, Stanson AW, Daniels BK, Sheedy PF (1996) Effects of changes in central venous pressure on upper airway size in patients with obstructive sleep apnea. Am J Respir Crit Care Med 153:250–254

    Article  PubMed  Google Scholar 

  19. Chiu KL, Ryan CM, Shiota S, Ruttanaumpawan P, Arzt M, Haight JS, Chan CT, Floras JS, Bradley TD (2006) Fluid shift by lower body positive pressure increases pharyngeal resistance in healthy subjects. Am J Respir Crit Care Med 174:1378–1383

    Article  PubMed  Google Scholar 

  20. Su MC, Chiu KL, Ruttanaumpawan P, Shiota S, Yumino D, Redolfi S, Haight JS, Bradley TD (2008) Lower body positive pressure increases upper airway collapsibility in healthy subjects. Respir Physiol Neurobiol 161:306–312

    Article  PubMed  Google Scholar 

  21. Shiota S, Ryan CM, Chiu KL, Ruttanaumpawan P, Haight J, Arzt M, Floras JS, Chan C, Bradley TD (2007) Alterations in upper airway cross-sectional area in response to lower body positive pressure in healthy subjects. Thorax 62:868–872

    Article  PubMed  Google Scholar 

  22. Su MC, Chiu KL, Ruttanaumpawan P, Shiota S, Yumino D, Redolfi S, Haight JS, Yau B, Lam J, Bradley TD (2007) Difference in upper airway collapsibility during wakefulness between men and women in response to lower-body positive pressure. Clin Sci (Lond) 116:713–720

    Article  Google Scholar 

  23. Redolfi S, Yumino D, Ruttanaumpawan P, Yau B, Su MC, Lam J, Bradley TD (2009) Relationship between overnight rostral fluid shift and obstructive sleep apnea in nonobese men. Am J Respir Crit Care Med 179:241–246

    Article  PubMed  Google Scholar 

  24. Redolfi S, Arnulf I, Pottier M, Bradley TD, Similowski T (2011) Effects of venous compression of the legs on overnight rostral fluid shift and obstructive sleep apnea. Respir Physiol Neurobiol 175:390–393

    Article  PubMed  Google Scholar 

  25. Redolfi S, Arnulf I, Pottier M, Lajou J, Koskas I, Bradley TD, Similowski T (2011) Attenuation of obstructive sleep apnea by compression stockings in subjects with venous insufficiency. Am J Respir Crit Care Med 184:1062–1066

    Article  PubMed  Google Scholar 

  26. Giebelhaus V, Strohl KP, Lormes W, Lehmann M, Netzer N (2000) Physical exercise as an adjunct therapy in sleep apnea—an open trial. Sleep Breath 4:173–176

    PubMed  Google Scholar 

  27. Quan SF, O'Connor GT, Quan JS, Redline S, Resnick HE, Shahar E, Siscovick D, Sherrill DL (2007) Association of physical activity with sleep-disordered breathing. Sleep Breath 11:149–157

    Article  PubMed  Google Scholar 

  28. Kline CE, Crowley EP, Ewing GB, Burch JB, Blair SN, Durstine JL, Davis JM, Youngstedt SD (2011) The effect of exercise training on obstructive sleep apnea and sleep quality: a randomized controlled trial. Sleep 34:1631–1640

    PubMed  Google Scholar 

  29. Sengul YS, Ozalevli S, Oztura I, Itil O, Baklan B (2011) The effect of exercise on obstructive sleep apnea: a randomized and controlled trial. Sleep Breath 15:49–56

    Article  PubMed  Google Scholar 

  30. Peppard PE, Young T (2004) Exercise and sleep-disordered breathing: an association independent of body habitus. Sleep 27:480–484

    PubMed  Google Scholar 

  31. Winkel J (1981) Swelling of the lower leg in sedentary work—a pilot study. J Hum Ergol (Tokyo) 10:139–149

    CAS  Google Scholar 

  32. Awad KM, Malhotra A, Barnet JH, Quan SF, Peppard PE (2012) Exercise is associated with a reduced incidence of sleep-disordered breathing. Am J Med 125:485–490

    Article  PubMed  Google Scholar 

  33. Jafari B, Mohsenin V (2011) Overnight rostral fluid shift in obstructive sleep apnea: does it affect the severity of sleep-disordered breathing? Chest 140:991–997

    Article  PubMed  Google Scholar 

  34. Calhoun DA, Jones D, Textor S, Goff DC, Murphy TP, Toto RD, White A, Cushman WC, White W, Sica D, Ferdinand K, Giles TD, Falkner B, Carey RM (2008) Resistant hypertension: diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension 51:1403–1419

    Article  PubMed  CAS  Google Scholar 

  35. Isaksson H, Svanborg E (1991) Obstructive sleep apnea syndrome in male hypertensives, refractory to drug therapy. Nocturnal automatic blood pressure measurements—an aid to diagnosis? Clin Exp Hypertens A 13:1195–1212

    Article  PubMed  CAS  Google Scholar 

  36. Logan AG, Perlikowski SM, Mente A, Tisler A, Tkacova R, Niroumand M, Leung RS, Bradley TD (2001) High prevalence of unrecognized sleep apnoea in drug-resistant hypertension. J Hypertens 19:2271–2277

    Article  PubMed  CAS  Google Scholar 

  37. Gonçalves SC, Martinez D, Gus M, de Abreu-Silva EO, Bertoluci C, Dutra I, Branchi T, Moreira LB, Fuchs SC, de Oliveira AC, Fuchs FD (2007) Obstructive sleep apnea and resistant hypertension: a case–control study. Chest 132:1858–1862

    Article  PubMed  Google Scholar 

  38. Lavie P, Hoffstein V (2001) Sleep apnea syndrome: a possible contributing factor to resistant. Sleep 24:721–725

    PubMed  CAS  Google Scholar 

  39. Ruttanaumpawan P, Nopmaneejumruslers C, Logan AG, Lazarescu A, Qian I, Bradley TD (2009) Association between refractory hypertension and obstructive sleep apnea. J Hypertens 27:1439–1445

    Article  PubMed  CAS  Google Scholar 

  40. Grote L, Hedner J, Peter JH (2000) Sleep-related breathing disorder is an independent risk factor for uncontrolled hypertension. J Hypertens 18:679–685

    Article  PubMed  CAS  Google Scholar 

  41. Pedrosa RP, Drager LF, Gonzaga CC, Sousa MG, de Paula LK, Amaro AC, Amodeo C, Bortolotto LA, Krieger EM, Bradley TD, Lorenzi-Filho G (2011) Obstructive sleep apnea: the most common secondary cause of hypertension associated with resistant hypertension. Hypertension 58:811–817

    Article  PubMed  CAS  Google Scholar 

  42. Gus M, Silva DN, Fernandes J, Cunha CP, Sant'Anna GD (2002) Epworth's Sleepiness Scale in outpatients with different values of arterial blood pressure. Arq Bras Cardiol 78:17–24

    PubMed  Google Scholar 

  43. Gus M, Gonçalves SC, Martinez D, de Abreu Silva EO, Moreira LB, Fuchs SC, Fuchs FD (2008) Risk for obstructive sleep apnea by Berlin Questionnaire, but not daytime sleepiness, is associated with resistant hypertension: a case–control study. Am J Hypertens 21:832–835

    Article  PubMed  Google Scholar 

  44. Drager LF, Genta PR, Pedrosa RP, Nerbass FB, Gonzaga CC, Krieger EM, Lorenzi-Filho G (2010) Characteristics and predictors of obstructive sleep apnea in patients with systemic hypertension. Am J Cardiol 105:1135–1139

    Article  PubMed  Google Scholar 

  45. Lloberes P, Lozano L, Sampol G, Romero O, Jurado MJ, Ríos J, Untoria MD, Tovar JL (2010) Obstructive sleep apnoea and 24-h blood pressure in patients with resistant hypertension. J Sleep Res 19:597–602

    Article  PubMed  Google Scholar 

  46. Logan AG, Tkacova R, Perlikowski SM, Leung RS, Tisler A, Floras JS, Bradley TD (2003) Refractory hypertension and sleep apnoea: effect of CPAP on blood pressure and baroreflex. Eur Respir J 21:241–247

    Article  PubMed  CAS  Google Scholar 

  47. Lozano L, Tovar JL, Sampol G, Romero O, Jurado MJ, Segarra A, Espinel E, Ríos J, Untoria MD, Lloberes P (2010) Continuous positive airway pressure treatment in sleep apnea patients with resistant hypertension: a randomized, controlled trial. J Hypertens 28:2161–2168

    PubMed  CAS  Google Scholar 

  48. Dernaika TA, Kinasewitz GT, Tawk MM (2009) Effects of nocturnal continuous positive airway pressure therapy in patients with resistant hypertension and obstructive sleep apnea. J Clin Sleep Med 5:103–107

    PubMed  Google Scholar 

  49. Demede M, Pandey A, Zizi F, Bachmann R, Donat M, McFarlane SI, Jean-Louis G, Ogedegbe G (2011) Resistant hypertension and obstructive sleep apnea in the primary-care setting. Int J Hypertens 2011:340929

    PubMed  CAS  Google Scholar 

  50. Friedman O, Bradley TD, Ruttanaumpawan P, Logan AG (2010) Independent association of drug-resistant hypertension to reduced sleep duration and efficiency. Am J Hypertens 23:174–179

    Article  PubMed  Google Scholar 

  51. Calhoun DA, Nishizaka MK, Zaman MA, Harding SM (2004) Aldosterone excretion among subjects with resistant hypertension and symptoms of sleep apnea. Chest 125:112–117

    Article  PubMed  CAS  Google Scholar 

  52. Gonzaga CC, Gaddam KK, Ahmed MI, Pimenta E, Thomas SJ, Harding SM, Oparil S, Cofield SS, Calhoun DA (2010) Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension. J Clin Sleep Med 6:363–368

    PubMed  Google Scholar 

  53. Gaddam K, Pimenta E, Thomas SJ, Cofield SS, Oparil S, Harding SM, Calhoun DA (2010) Spironolactone reduces severity of obstructive sleep apnoea in patients with resistant hypertension: a preliminary report. J Hum Hypertens 24:532–537

    Article  PubMed  CAS  Google Scholar 

  54. Friedman O, Bradley TD, Chan CT, Parkes R, Logan AG (2010) Relationship between overnight rostral fluid shift and obstructive sleep apnea in drug-resistant hypertension. Hypertension 56:1077–1082

    Article  PubMed  CAS  Google Scholar 

  55. Witkowski A, Prejbisz A, Florczak E, Kądziela J, Śliwiński P, Bieleń P, Michałowska I, Kabat M, Warchoł E, Januszewicz M, Narkiewicz K, Somers VK, Sobotka PA, Januszewicz A (2011) Effects of renal sympathetic denervation on blood pressure, sleep apnea course, and glycemic control in patients with resistant hypertension and sleep apnea. Hypertension 58:559–565

    Article  PubMed  CAS  Google Scholar 

  56. Coats AJ (2011) Clinical utility of exercise training in chronic systolic heart failure. Nat Rev Cardiol 8:380–392

    Article  PubMed  Google Scholar 

  57. Hayes D Jr, Anstead MI, Ho J, Phillips BA (2009) Insomnia and chronic heart failure. Heart Fail Rev 14:171–182

    Article  PubMed  Google Scholar 

  58. Ferreira S, Marinho A, Patacho M, Santa-Clara E, Carrondo C, Winck J, Bettencourt P (2010) Prevalence and characteristics of sleep apnoea in patients with stable heart failure: results from a heart failure clinic. BMC Pulm Med 10:9

    Article  PubMed  CAS  Google Scholar 

  59. Patidar AB, Andrews GR, Seth S (2011) Prevalence of obstructive sleep apnea, associated risk factors, and quality of life among Indian congestive heart failure patients: a cross-sectional survey. J Cardiovasc Nurs 26:452–459

    PubMed  Google Scholar 

  60. Herrscher TE, Akre H, Øverland B, Sandvik L, Westheim AS (2011) High prevalence of sleep apnea in heart failure outpatients: even in patients with preserved systolic function. J Card Fail 17:420–425

    Article  PubMed  Google Scholar 

  61. Redeker NS, Muench U, Zucker MJ, Walsleben J, Gilbert M, Freudenberger R, Chen M, Campbell D, Blank L, Berkowitz R, Adams L, Rapoport DM (2010) Sleep disordered breathing, daytime symptoms, and functional performance in stable heart failure. Sleep 33:551–560

    PubMed  Google Scholar 

  62. Yumino D, Wang H, Floras JS, Newton GE, Mak S, Ruttanaumpawan P, Parker JD, Bradley TD (2009) Prevalence and physiological predictors of sleep apnea in patients with heart failure and systolic dysfunction. J Card Fail 15:279–285

    Article  PubMed  Google Scholar 

  63. Jun JC, Drager LF, Najjar SS, Gottlieb SS, Brown CD, Smith PL, Schwartz AR, Polotsky VY (2011) Effects of sleep apnea on nocturnal free fatty acids in subjects with heart failure. Sleep 34:1207–1213

    PubMed  Google Scholar 

  64. Yumino D, Wang H, Floras JS, Newton GE, Mak S, Ruttanaumpawan P, Parker JD, Bradley TD (2009) Relationship between sleep apnoea and mortality in patients with ischaemic heart failure. Heart 95:819–824

    Article  PubMed  CAS  Google Scholar 

  65. Walsh JT, Andrews R, Starling R, Cowley AJ, Johnston ID, Kinnear WJ (1995) Effects of captopril and oxygen on sleep apnoea in patients with mild to moderate congestive cardiac failure. Br Heart J 73:237–241

    Article  PubMed  CAS  Google Scholar 

  66. Bucca CB, Brussino L, Battisti A, Mutani R, Rolla G, Mangiardi L, Cicolin A (2007) Diuretics in obstructive sleep apnea with diastolic heart failure. Chest 132:440–446

    Article  PubMed  Google Scholar 

  67. Yumino D, Redolfi S, Ruttanaumpawan P, Su MC, Smith S, Newton GE, Mak S, Bradley TD (2010) Nocturnal rostral fluid shift: a unifying concept for the pathogenesis of obstructive and central sleep apnea in men with heart failure. Circulation 121:1598–1605

    Article  PubMed  Google Scholar 

  68. Kasai T, Arcand J, Allard JP, Mak S, Azevedo ER, Newton GE, Bradley TD (2011) Relationship between sodium intake and sleep apnea in patients with heart failure. J Am Coll Cardiol 58:1970–1974

    Article  PubMed  CAS  Google Scholar 

  69. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, Van Lente F, Levey AS (2007) Prevalence of chronic kidney disease in the United States. JAMA 298:2038–2047

    Article  PubMed  CAS  Google Scholar 

  70. Unruh ML, Sanders MH, Redline S, Piraino BM, Umans JG, Chami H, Budhiraja R, Punjabi NM, Buysse D, Newman AB (2008) Subjective and objective sleep quality in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the Sleep Heart Health Study. Am J Kidney Dis 52:305–313

    Article  PubMed  Google Scholar 

  71. Araujo SM, Bruin VM, Daher EF, Medeiros CA, Almeida GH, Bruin PF (2011) Quality of sleep and day-time sleepiness in chronic hemodialysis: a study of 400 patients. Scand J Urol Nephrol 45:359–364

    Article  PubMed  Google Scholar 

  72. Erten Y, Kokturk O, Yuksel A, Elbeg S, Ciftci TU, Pasaoglu H, Ozkan S, Bali M, Arinsoi T, Sindel S (2005) Relationship between sleep complaints and proinflammatory cytokines in haemodialysis patients. Nephrology (Carlton) 10:330–335

    Article  CAS  Google Scholar 

  73. Kuhlmann U, Becker HF, Birkhahn M, Peter JH, von Wichert P, Schütterle S, Lange H (2000) Sleep-apnea in patients with end-stage renal disease and objective results. Clin Nephrol 53:460–466

    PubMed  CAS  Google Scholar 

  74. Markou N, Kanakaki M, Myrianthefs P, Hadjiyanakos D, Vlassopoulos D, Damianos A, Siamopoulos K, Vasiliou M, Konstantopoulos S (2006) Sleep-disordered breathing in nondialyzed patients with chronic renal failure. Lung 184:43–49

    Article  PubMed  Google Scholar 

  75. Tada T, Kusano KF, Ogawa A, Iwasaki J, Sakuragi S, Kusano I, Takatsu S, Miyazaki M, Ohe T (2007) The predictors of central and obstructive sleep apnoea in haemodialysis patients. Nephrol Dial Transplant 22:1190–1197

    Article  PubMed  Google Scholar 

  76. Iseki K, Tohyama K, Matsumoto T, Nakamura H (2007) High prevalence of chronic kidney disease among patients with sleep related breathing disorder (SRBD). Hypertens Res 31:249–255

    Article  Google Scholar 

  77. Sakaguchi Y, Shoji T, Kawabata H, Niihata K, Suzuki A, Kaneko T, Okada N, Isaka Y, Rakugi H, Tsubakihara Y (2011) High prevalence of obstructive sleep apnea and its association with renal function among nondialysis chronic kidney disease patients in Japan: a cross-sectional study. Clin J Am Soc Nephrol 6:995–1000

    Article  PubMed  Google Scholar 

  78. Canales MT, Paudel ML, Taylor BC, Ishani A, Mehra R, Steffes M, Stone KL, Redline S, Ensrud KE (2011) Sleep-disordered breathing and urinary albumin excretion in older men. Sleep Breath 15:137–144

    Article  PubMed  Google Scholar 

  79. Kato K, Takata Y, Usui Y, Shiina K, Asano K, Hashimura Y, Saruhara H, Nishihata Y, Tomiyama H, Yamashina A (2011) Severe obstructive sleep apnea increases cystatin C in clinically latent renal dysfunction. Respir Med 105:643–649

    Article  PubMed  Google Scholar 

  80. Ahmed SB, Ronksley PE, Hemmelgarn BR, Tsai WH, Manns BJ, Tonelli M, Klarenbach SW, Chin R, Clement FM, Hanly PJ (2011) Nocturnal hypoxia and loss of kidney function. PLoS One 6(4):e19029

    Article  PubMed  CAS  Google Scholar 

  81. Kanbay A, Buyukoglan H, Ozdogan N, Kaya E, Oymak FS, Gulmez I, Demir R, Kokturk O, Covic A (2011) Obstructive sleep apnea syndrome is related to the progression of chronic kidney disease. Int Urol Nephrol 44:535–539

    Article  PubMed  CAS  Google Scholar 

  82. Chou YT, Lee PH, Yang CT, Lin CL, Veasey S, Chuang LP, Lin SW, Lin YS, Chen NH (2011) Obstructive sleep apnea: a stand-alone risk factor for chronic kidney disease. Nephrol Dial Transplant 26:2244–2250

    Article  PubMed  Google Scholar 

  83. Szentkiralyi A, Czira ME, Molnar MZ, Kovesdy CP, Remport A, Szeifert L, Vamos EP, Juhasz J, Turanyi CZ, Mucsi I, Novak M (2011) High risk of obstructive sleep apnea is a risk factor of death censored graft loss in kidney transplant recipients: an observational cohort study. Sleep Med 12:267–273

    Article  PubMed  Google Scholar 

  84. Jung HH, Han H, Lee JH (2005) Sleep apnea, coronary artery disease, and antioxidant status in hemodialysis patients. Am J Kidney Dis 45:875–882

    Article  PubMed  Google Scholar 

  85. Koehnlein T, Schmidt A, Moesenthin M, Dierkes J, Neumann KH, Welte T (2009) Increased cardiac troponin T and C-reactive protein levels in end-stage renal disease are associated with obstructive sleep apnea. Clin Nephrol 71:50–58

    PubMed  CAS  Google Scholar 

  86. Tang SC, Lam B, Yao TJ, Leung WS, Chu CM, Ho YW, Ip MS, Lai KN (2010) Sleep apnea is a novel risk predictor of cardiovascular morbidity and death in patients receiving peritoneal dialysis. Kidney Int 77:1031–1038

    Article  PubMed  Google Scholar 

  87. Jung HH, Lee JH, Baek HJ, Kim SJ, Lee JJ (2010) Nocturnal hypoxemia and periodic limb movement predict mortality in patients on maintenance hemodialysis. Clin J Am Soc Nephrol 5:1607–1613

    Article  PubMed  Google Scholar 

  88. Masuda T, Murata M, Honma S, Iwazu Y, Sasaki N, Ogura M, Onishi A, Ando Y, Muto S, Shimada K, Kario K, Kusano E, Asano Y (2011) Sleep-disordered breathing predicts cardiovascular events and mortality in hemodialysis patients. Nephrol Dial Transplant 26:2289–2295

    Article  PubMed  Google Scholar 

  89. Jurado-Gamez B, Martin-Malo A, Alvarez-Lara MA, Muñoz L, Cosano A, Aljama P (2007) Sleep disorders are underdiagnosed in patients on maintenance hemodialysis. Nephron Clin Pract 105:c35–42

    Article  PubMed  CAS  Google Scholar 

  90. Beecroft JM, Pierratos A, Hanly PJ (2009) Clinical presentation of obstructive sleep apnea in patients with end-stage renal disease. J Clin Sleep Med 5:115–121

    PubMed  Google Scholar 

  91. Canales MT, Taylor BC, Ishani A, Mehra R, Steffes M, Stone KL, Redline S, Ensrud KE (2008) Reduced renal function and sleep-disordered breathing in community-dwelling elderly men. Sleep Med 9:637–645

    Article  PubMed  Google Scholar 

  92. Canales MT, Lui LY, Taylor BC, Ishani A, Mehra R, Stone KL, Redline S, Ensrud KE (2008) Renal function and sleep-disordered breathing in older men. Nephrol Dial Transplant 23:3908–3914

    Article  PubMed  Google Scholar 

  93. Rule AD, Larson TS, Bergstralh EJ, Slezak JM, Jacobsen SJ, Cosio FG (2004) Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. Ann Intern Med 141:929–937

    Article  PubMed  CAS  Google Scholar 

  94. Sim JJ, Rasgon SA, Kujubu DA, Kumar VA, Liu IL, Shi JM, Pham TT, Derose SF (2009) Sleep apnea in early and advanced chronic kidney disease: Kaiser Permanente Southern California Cohort. Chest 135:710–716

    Article  PubMed  Google Scholar 

  95. Nicholl DD, Ahmed SB, Loewen AH, Hemmelgarn BR, Sola DY, Beecroft JM, Turin TC, Hanly PJ (2012) Declining kidney function increases the prevalence of sleep apnea and nocturnal hypoxia. Chest 141:1422–1430

    Article  PubMed  Google Scholar 

  96. Molnar MZ, Szentkiralyi A, Lindner A, Czira ME, Szabo A, Mucsi I, Novak M (2007) High prevalence of patients with a high risk for obstructive sleep apnoea syndrome after kidney transplantation—association with declining renal function. Nephrol Dial Transplant 22:2686–2692

    Article  PubMed  Google Scholar 

  97. Hanly PJ, Pierratos A (2001) Improvement of sleep apnea in patients with chronic renal failure who undergo nocturnal hemodialysis. N Engl J Med 344:102–107

    Article  PubMed  CAS  Google Scholar 

  98. Beecroft JM, Hoffstein V, Pierratos A, Chan CT, McFarlane PA, Hanly PJ (2007) Pharyngeal narrowing in end-stage renal disease: implications for obstructive sleep apnoea. Eur Respir J 30:965–971

    Article  PubMed  CAS  Google Scholar 

  99. Beecroft JM, Hoffstein V, Pierratos A, Chan CT, McFarlane P, Hanly PJ (2008) Nocturnal haemodialysis increases pharyngeal size in patients with sleep apnoea and end-stage renal disease. Nephrol Dial Transplant 23:673–679

    Article  PubMed  Google Scholar 

  100. Tang SC, Lam B, Lai AS, Pang CB, Tso WK, Khong PL, Ip MS, Lai KN (2009) Improvement in sleep apnea during nocturnal peritoneal dialysis is associated with reduced airway congestion and better uremic clearance. Clin J Am Soc Nephrol 4:410–418

    Article  PubMed  Google Scholar 

  101. Beecroft JM, Duffin J, Pierratos A, Chan CT, McFarlane P, Hanly PJ (2009) Decreased chemosensitivity and improvement of sleep apnea by nocturnal hemodialysis. Sleep Med 10:47–54

    Article  PubMed  Google Scholar 

  102. Chan CT, Hanly P, Gabor J, Picton P, Pierratos A, Floras JS (2004) Impact of nocturnal hemodialysis on the variability of heart rate and duration of hypoxemia during sleep. Kidney Int 65:661–665

    Article  PubMed  Google Scholar 

  103. Langevin B, Fouque D, Léger P, Robert D (1993) Sleep apnea syndrome and end-stage renal disease. Cure after renal transplantation. Chest 103:1330–1335

    Article  PubMed  CAS  Google Scholar 

  104. Beecroft JM, Zaltzman J, Prasad R, Meliton G, Hanly PJ (2007) Impact of kidney transplantation on sleep apnoea in patients with end-stage renal disease. Nephrol Dial Transplant 22:3028–3033

    Article  PubMed  Google Scholar 

  105. Rodrigues CJ, Marson O, Togeiro SM, Tufik S, Ribeiro AB, Tavares A (2010) Sleep-disordered breathing changes after kidney transplantation: a polysomnographic study. Nephrol Dial Transplant 25:2011–2015

    Article  PubMed  Google Scholar 

  106. Jurado-Gámez B, Martin-Malo A, Rodriguez-Benot A, Muñoz-Cabrera L, Cosano Povedano A, Aljama P (2008) Kidney transplantation improves sleep-related breathing in hemodialysis patients. Blood Purif 26:485–490

    Article  PubMed  Google Scholar 

  107. Lee JJ, Kim GS, Kim JA, Kim SJ, Kang JG, Kim GH, Jung HH (2011) Improvement of sleep-related breathing disorder in patients with end-stage renal disease after kidney transplantation. Clin Transplant 25:126–130

    Article  PubMed  Google Scholar 

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  1. Kyrgyz State Medical Academy named after I.K. Akhunbaev, Akhunbaev Street 92, Bishkek, 720020, Kyrgyzstan

    Aibek E. Mirrakhimov

  2. National Centre of Cardiology and Internal Medicine named after М.M. Mirrakhimov, T.Moldo Street 3, Bishkek, 720040, Kyrgyzstan

    Aibek E. Mirrakhimov

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Mirrakhimov, A.E. Supine fluid redistribution: should we consider this as an important risk factor for obstructive sleep apnea?. Sleep Breath 17, 511–523 (2013). https://doi.org/10.1007/s11325-012-0755-6

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  • DOI: https://doi.org/10.1007/s11325-012-0755-6

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