Abstract
Correlation between obesity and obstructive sleep apnea has been documented in both adults and children. This investigation evaluated importance of body mass index (BMI) in relation to age as predictor of severity of obstructive sleep-disordered breathing (SDB). Children with habitual snoring referred for polysomnography were recruited. BMI Z score (≥1.036 vs <1.036, i.e. at risk for overweight or overweight vs normal) was assessed as predictor of severity of SDB (apnea-hypopnea index [AHI] >five vs ≤five episodes per hour) at different ages (≤6 vs >6 years). Two hundered eighty-four participants were recruited: 75 young children (4.6 ± 1 years) with high BMI (1.9 ± 0.7); 95 young subjects (4.5 ± 1.1 years) with low BMI (−0.2 ± 1.3); 55 older children (9.2 ± 1.8 years) with high BMI (1.8 ± 0.5); and 59 older participants (9.7 ± 2.2 years) with low BMI (−0.2 ± 1.1). Odds ratios for AHI >5 in young/high BMI children, young/low BMI subjects, and older/high BMI subjects relative to older/low BMI participants were: 6.5 (95% confidence interval 2.1–19.9), 7.3 (2.4–22) and 2 (0.6–7.3), respectively. Large tonsil size was associated with young age (odds ratio 1.97; 1.2–3.3). Among children with habitual snoring, adiposity does not predict severity of obstructive SDB in early childhood probably due to the prominent role of adenotonsillar hypertrophy. However, it may have a more important contribution to severity of SDB in older children.
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Kaditis, A.G., Alexopoulos, E.I., Hatzi, F. et al. Adiposity in relation to age as predictor of severity of sleep apnea in children with snoring. Sleep Breath 12, 25–31 (2008). https://doi.org/10.1007/s11325-007-0132-z
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DOI: https://doi.org/10.1007/s11325-007-0132-z