Abstract
The obstructive sleep apnea–hypopnea syndrome (OSAHS) is a common sleep-related breathing disorder characterized by repetitive obstructions of the upper airway during sleep. The modification of pharyngeal patency by oral appliance therapy has been suggested as an alternative to various treatment modalities for OSAHS. To determine the evidence base with respect to the efficacy and comorbidity of the oral appliance therapy in OSAHS, a systematic review of the available literature was conducted. In addition, the preliminary results of a randomized parallel trial are reported on the effectiveness and specific indication of, respectively, the oral appliance and continuous positive airways pressure therapy in OSAHS.
References
Sindhu F, Carpenter L, Seers K (1997) Development of a tool to rate the quality assessment of randomized controlled trials using a Delphi technique. J Adv Nurs 25:1262–1268
White J, Cates C, Wright J (2001) Continuous positive airways pressure for obstructive sleep apnoea. The Cochrane Database of Systematic Reviews (4): Art. No.: CD001106. DOI: 10.1002/14651858.CD001106
Cistulli PA, Gotsopoulos H, Marklund M, Lowe AA (2004) Treatment of snoring and obstructive sleep apnea with mandibular repositioning appliances. Sleep Med Rev 8:443–457
Hoekema A, Stegenga B, De Bont LG (2004) Efficacy and co-morbidity of oral appliances in the treatment of obstructive sleep apnea–hypopnea: a systematic review. Crit Rev Oral Biol Med 15:137–155
Lim J, Lasserson TJ, Fleetham J, Wright J (2004) Oral appliances for obstructive sleep apnoea. The Cochrane Database of Systematic Reviews (4): Art. No.: CD004435. DOI: 10.1002/ 14651858. CD004435. pub2
Tegelberg A, Walker-Engstrom ML, Vestling O, Wilhelmsson B (2003) Two different degrees of mandibular advancement with a dental appliance in treatment of patients with mild to moderate obstructive sleep apnea. Acta Odontol Scand 6:356–362
Barnes M, McEvoy RD, Banks S, Tarquinio N, Murray CG, Vowles N, Pierce RJ (2004) Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea. Am J Respir Crit Care Med 170:656–664
Blanco J, Zamarron C, Abeleira Pazos MT, Lamela C, Suarez Quintanilla D (2005) Prospective evaluation of an oral appliance in the treatment of obstructive sleep apnea syndrome. Sleep Breath 9:20–25
Lawton HM, Battagel JM, Kotecha B (2005) A comparison of the Twin Block and Herbst mandibular advancement splints in the treatment of patients with obstructive sleep apnoea: a prospective study. Eur J Orthod 27:82–90
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Hoekema, A. Efficacy and comorbidity of oral appliances in the treatment of obstructive sleep apnea–hypopnea: a systematic review and preliminary results of a randomized trial. Sleep Breath 10, 102–103 (2006). https://doi.org/10.1007/s11325-005-0048-4
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11325-005-0048-4