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Variation of Antioxidant Activity in Dreissena polymorpha Specimens Exposed to 2,2′,4,4′,5,6′-Hexa BDE (BDE-154)

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Abstract

We evaluated the imbalance of the oxidative status in zebra mussel (Dreissena polymorpha) specimens exposed for 96 h to environmentally relevant concentrations (0.1, 0.5, and 1 μg/L) of the 2,2′,4,4′,5,6′-hexa BDE (BDE-154). The activities of three antioxidant enzymes, catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), and the phase II detoxifying enzyme glutathione S-transferase (GST), were measured in the cytosolic fraction from a pool of zebra mussels. Significant variations in the activity of each single enzyme were noticed at each treatment, indicating that exposure to BDE-154 was able to impair the oxidative status of treated bivalves through the increase of reactive oxygen species. In detail, SOD and GPx were significantly induced, while CAT and GST were depressed with respect to the baseline levels. These data have confirmed that the raise of oxidative stress is the main cause of the BDE-154-induced genetic damage observed in a previous study on the zebra mussel.

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  1. Department of Biology, University of Milan, Via Celoria 26, 20133, Milan, Italy

    Marco Parolini, Alessandra Pedriali & Andrea Binelli

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  1. Marco Parolini
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  2. Alessandra Pedriali
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Correspondence to Marco Parolini.

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Parolini, M., Pedriali, A. & Binelli, A. Variation of Antioxidant Activity in Dreissena polymorpha Specimens Exposed to 2,2′,4,4′,5,6′-Hexa BDE (BDE-154). Water Air Soil Pollut 223, 3067–3076 (2012). https://doi.org/10.1007/s11270-012-1089-5

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