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Caraparu virus (group C Orthobunyavirus): sequencing and phylogenetic analysis based on the conserved region 3 of the RNA polymerase gene

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Abstract

Here, for the first time, we report the nucleotide sequence of Caraparu virus (CARV) L segment and the analysis of the RNA polymerase region 3 encoded by this segment. The 1,404 bp nucleotide sequence shares the highest identity with Bunyamwera, La Crosse, Oropouche, and Akabane virus sequences. The amino acid sequence was deduced and aligned with sequences from members of the Bunyaviridae family and used for phylogenetic analysis. The CARV clustered in the Orthobunyavirus genus. The premotif A and motifs A–E are present in the region 3 of the Bunyaviridae family, were also conserved in CARV L protein, as well as other conserved regions among Orthobunyavirus genus.

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Acknowledgments

This work was financially supported by FAPEMIG. C.L.B. Magalhães received fellowships from CAPES, J.R. Santos, R.F.V. Novaes, E.G. Kroon, C.A. Bonjardim, and P.C.P. Ferreira from CNPq, and B.R. Quinan from FAPEMIG. We thank Betânia P. Drumond for help in the sequence data and for scientific assistance and Jaquelline G. Oliveira for critical reading of the manuscript.

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Authors and Affiliations

  1. Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Campus Pampulha, CEP: 31270-901, Belo Horizonte, Minas Gerais, Brazil

    Cintia Lopes de Brito Magalhães, Bárbara Resende Quinan, Renata Franco Vianna Novaes, João Rodrigues dos Santos, Erna Geessien Kroon, Cláudio Antônio Bonjardim & Paulo César Peregrino Ferreira

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  1. Cintia Lopes de Brito Magalhães
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  2. Bárbara Resende Quinan
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  3. Renata Franco Vianna Novaes
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  4. João Rodrigues dos Santos
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  5. Erna Geessien Kroon
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  6. Cláudio Antônio Bonjardim
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  7. Paulo César Peregrino Ferreira
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Corresponding author

Correspondence to Paulo César Peregrino Ferreira.

Additional information

The nucleotide sequence data reported in this article have been submitted to the GenBank nucleotide sequence database: EF122411

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de Brito Magalhães, C.L., Quinan, B.R., Novaes, R.F.V. et al. Caraparu virus (group C Orthobunyavirus): sequencing and phylogenetic analysis based on the conserved region 3 of the RNA polymerase gene. Virus Genes 35, 681–684 (2007). https://doi.org/10.1007/s11262-007-0138-4

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  • DOI: https://doi.org/10.1007/s11262-007-0138-4

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