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A fatal suppurative pneumonia in piglets caused by a pathogenic coagulase-positive strain of Staphylococcus hyicus

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Abstract

Staphylococcus hyicus is one of the opportunistic pathogens that cause infections to animals. Early studies have demonstrated that S. hyicus is the causative agents of exudative epidermitis in pigs, arthritis in horses and chicken, mastitis in cow, and bacteremia, sepsis and multiple organ failure in humans. Here, we report the isolation and identification of a representative S. hyicus isolate, named JLHN15, from a pig farm with a disease characterized by bacteremia, suppurative pneumonia and fibrinous pericarditis. Our results indicate that JLHN15 is a pathogenic coagulase-positive Staphylococcus. To the best knowledge, this is the first report of S. hyicus causing an infection characterized by suppurative pneumonia and sepsis.

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References

  • Andresen LO, Ahrens P (2004) A multiplex PCR for detection of genes encoding exfoliative toxins from staphylococcus hyicus. J Appl Microbiol 96:1265–1270

    Article  CAS  PubMed  Google Scholar 

  • Andresen LO, Bille-Hansen V, Wegener HC (1997) Staphylococcus hyicus exfoliative toxin: purification and demonstration of antigenic diversity among toxins from virulent strains. Microb Pathog 22:113–122

    Article  CAS  PubMed  Google Scholar 

  • Bao XH, Cao CB, Zhou FZ, Zhang J, Sun R (2008) Two rare cases of multiple organ failure of human caused by Staphylococcus hyicus. J Clin Intern Med 25:826–827

    Google Scholar 

  • Casanova C, Iselin L, von Steiger N, Droz S, Sendi P (2011) Staphylococcus hyicus bacteremia in a farmer. J Clin Microbiol 49:4377–4378

    Article  PubMed  PubMed Central  Google Scholar 

  • Cenci-Goga BT, Karama M, Rossitto PV, Morgante RA, Cullor JS (2003) Enterotoxin production by Staphylococcus aureus isolated from mastitic cows. J Food Prot 66:1693–1696

    Article  CAS  PubMed  Google Scholar 

  • Cuny C, Friedrich A, Kozytska S, Layer F, Nubel U (2010) Emergence of methicillin–resistant Staphylococcus aureus (MRSA) in different animal species. Int J Med Microbiol 300:109–117

    Article  PubMed  Google Scholar 

  • Devriese LA, Thelissen M (1986) Staphylococcus hyicus in donkeys. Vet Rec 118:76

    Article  CAS  PubMed  Google Scholar 

  • Devriese LA, Vlaminck K, Nuytten J, De Keersmaecker P (1983) Staphylococcus hyicus in skin lesions of horses. Equine Vet J 15:263–265

    Article  CAS  PubMed  Google Scholar 

  • Khanna T, Friendship R, Dewey C, Weese JS (2008) Methicillin resistant Staphylococcus aureus colonization in pigs and pig farmers. Vet Microbiol 128:298–303

    Article  CAS  PubMed  Google Scholar 

  • Kibenge FS, Rood JI, Wilcox GE (1983) Lysogeny and other characteristics of staphylococcus hyicus isolated from chickens. Vet Microbiol 8:411–415

    Article  CAS  PubMed  Google Scholar 

  • L'Ecuyer C (1967) Exudative epidermitis in pigs. Bacteriological studies on the causative agent. Can J Comp Med Vet Sci 31:243–247

    PubMed  PubMed Central  Google Scholar 

  • Park J, Friendship RM, Poljak Z, Weese JS, Dewey CE (2013) An investigation of exudative epidermitis (greasy pig disease) and antimicrobial resistance patterns of staphylococcus hyicus and Staphylococcus aureus isolated from clinical cases. Can Vet J 54:139–144

    PubMed  PubMed Central  Google Scholar 

  • Phillips WE Jr, King RE, Kloos WE (1980) Isolation of staphylococcus hyicus subsp hyicus from a pig with septic polyarthritis. Am J Vet Res 41:274–276

    PubMed  Google Scholar 

  • Saitou N, Nei M (1987) The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4:406–425

    CAS  PubMed  Google Scholar 

  • Schulz W (1970) Exudative epidermitis of the piglet (piglet eczema)--etiology and pathogenesis with special reference to staphylococcus hyicus. I. Literature review. Monatsh Veterinarmed 25:428–435

    CAS  PubMed  Google Scholar 

  • Takeuchi S, Kobayashi Y, Morozumi T, Niibori S (1985) Isolation and some properties of staphylococcus hyicus subsp. hyicus from pigs, chickens and cows. Nihon Juigaku Zasshi 47:841–843

    Article  CAS  PubMed  Google Scholar 

  • Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673–4680

  • Weese JS (2010) Methicillin-resistant Staphylococcus aureus in animals. ILAR J 51:233–244

    Article  CAS  PubMed  Google Scholar 

  • Wulf MW, Sorum M, van Nes A, Skov R, Melchers WJ et al (2008) Prevalence of methicillin-resistant Staphylococcus aureus among veterinarians: an international study. Clin Microbiol Infect 14:29–34

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

This study is supported by the Key Science and Technology projects from Jilin Province Science and Technology Program (20140204064NY) to Xinping Wang.

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Authors and Affiliations

  1. Key Laboratory for Zoonosis Research, Ministry of Education, Institute of Zoonosis, Jilin University, Changchun, China

    Mingyue Wang, Junying Hu, Lisai Zhu, Haibing Lu, Xin Li & Xinping Wang

  2. College of Veterinary Medicine, Jilin University, Changchun, Jilin, China

    Mingyue Wang, Junying Hu, Lisai Zhu, Chunguang Guo, Haibing Lu, Changming Guo, Xin Li & Xinping Wang

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  1. Mingyue Wang
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  2. Junying Hu
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  3. Lisai Zhu
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  4. Chunguang Guo
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  5. Haibing Lu
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  6. Changming Guo
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  7. Xin Li
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  8. Xinping Wang
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Correspondence to Xinping Wang.

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The authors declare that they have no conflict of interest.

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All animal procedures and experiments were approved by the Animal Ethics Committee of Jilin University following strict compliance with requirements of the Animal Ethics Procedures and Guidelines of the People’s Republic of China.

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Mingyue Wang, Jinying Hu, and Lisai Zhu contribute equally.

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Wang, M., Hu, J., Zhu, L. et al. A fatal suppurative pneumonia in piglets caused by a pathogenic coagulase-positive strain of Staphylococcus hyicus . Vet Res Commun 41, 139–146 (2017). https://doi.org/10.1007/s11259-017-9682-0

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  • DOI: https://doi.org/10.1007/s11259-017-9682-0

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