Skip to main content

Advertisement

SpringerLink
Log in

Re-emergence of multi-drug resistant Salmonella enterica serovar Stanley from cattle

  • Short communication
  • Published:
Veterinary Research Communications Aims and scope Submit manuscript

Abstract

During 2009, Salmonella enterica subspecies enterica serovar Stanley isolates were recovered from cattle diagnostic specimens in southern Japan, and the isolates were examined to characterize the genetic determinants involved in this new pathogenicity that associated with mortality in cattle. All the isolates were multi-drug resistance exhibited resistance to ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, oxytetracycline, and kanamycin (ACSSuT-Km) encoded by bla TEM, catA, aadA1, sul1, tet(A), and aphA1 genes, respectively. Class 1 integrons of 1.5-kb size were detected in all MDR isolates. The isolates harboured easily transferable plasmids of ca. 210-kb with the potential of transmitting resistance phenotype and genotype detected in the donor isolates. XbaI-digested PFGE patterns generated two related clusters implicated in the dissemination of multi-drug resistance amongst Salmonella Stanley isolates. An emergence of multi-drug resistant Salmonella Stanley amongst food-producing animals, including cattle is a threat to human health, as resistant isolates may be transmitted to humans through the food chain.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  • Ahmed AM, Ishida Y, Shimamoto T (2009) Molecular characterization of antimicrobial resistance in Salmonella isolated from animals in Japan. J Appl Microbiol 106:402–409

    Article  CAS  PubMed  Google Scholar 

  • Blood DC, Radostits OM (1989) Veterinary medicine: a text book of the diseases of cattle, sheep, pigs, goats and horses, 7th edn. Baillière Tindall, London, pp 643–657

    Google Scholar 

  • Centers for Disease Control and Prevention (CDC) (2007) Salmonella typhimurium infection associated with raw milk and cheese consumption-Pennsylvania. MMWR 56:1161–1164

    Google Scholar 

  • Collignon P, Wegener HC, Braam P, Butler CD (2005) The routine use of antibiotics to promote animal growth does little to benefit protein undernutrition in the developing world. Clin Infect Dis 41:1007–1013

    Article  PubMed  Google Scholar 

  • Dahshan H, Chuma T, Shahada F, Akiba M, Fujimoto H, Akasaka K, Kamimura Y, Okamoto K (2010a) Characterization of antibiotic resistance and the emergence of AmpC-producing salmonella infantis from pigs. J Vet Med Sci. In press

  • Dahshan H, Shahada F, Chuma T, Moriki H, Okamoto K (2010b) Genetic analysis of multidrug-resistant Salmonella enterica serovars Stanley and Typhimurium from cattle. Vet Microbiol 145:76–83

    Article  CAS  PubMed  Google Scholar 

  • Huang KY, Hong YW, Wang MH, Chu C, Su LH, Chiou CS, Chiu CH (2007) Molecular epidemiology and antimicrobial susceptibility of Salmonella enterica serotype Stanley isolates in Taiwan. J Microbiol Immunol Infect 40:411–418

    CAS  PubMed  Google Scholar 

  • Kado CI, Liu ST (1981) Rapid procedure for detection and isolation of large and small plasmids. J Bacteriol 145:1365–1373

    CAS  PubMed  Google Scholar 

  • Kirk MD, Little CL, Lem M, Fyfe M, Genobile D, Tan A, Threlfall J, Paccagnella A, Lightfoot D, Lyi H, McIntyre L, Ward L, Brown DJ, Surnam S, Fisher IS (2004) An outbreak due to peanuts in their shell caused by Salmonella enterica serotypes Stanley and Newport sharing molecular information to solve international outbreaks. Epidemiol Infect 132:571–577

    Article  CAS  PubMed  Google Scholar 

  • Mead PS, Slutsker L, Dietz V, McCaig LF, Bresee JS, Shapiro C, Griffin PM, Tauxe RV (1999) Food-related illness and death in the United States. Emerg Infect Dis 5:607–625

    Article  CAS  PubMed  Google Scholar 

  • National Committee for Clinical Laboratory Standards (NCCLS) (2002) Performance of standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from Animals; Approved Standard (M31-A2). 2nd ed. Wayne, PA

  • Ribot EM, Fair MA, Gautom R, Cameron DN, Hunter SB, Swaminathan B, Barrett TJ (2006) Standardization of pulsed-field gel electrophoresis protocols for the subtyping of Escherichia coli O157:H7, Salmonella, and Shigella for PulseNet. Foodborne Pathog Dis 3:59–67

    Article  CAS  PubMed  Google Scholar 

  • Tamura K, Dudley J, Nei M, Kumar S (2007) MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol 24:1596–1599

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Veterinary Public Health, Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0065, Japan

    Hesham Dahshan, Takehisa Chuma & Karoku Okamoto

  2. Department of Veterinary Public Health, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Sharkia Governorate, Egypt

    Hesham Dahshan & Mahdy A. Abd-El-Kader

  3. Kagoshima Livestock Hygiene Center, 1678 Hioki, Kagoshima, 899-2201, Japan

    Hiraku Moriki

Authors
  1. Hesham Dahshan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mahdy A. Abd-El-Kader
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Takehisa Chuma
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hiraku Moriki
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Karoku Okamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Hesham Dahshan or Takehisa Chuma.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dahshan, H., Abd-El-Kader, M.A., Chuma, T. et al. Re-emergence of multi-drug resistant Salmonella enterica serovar Stanley from cattle. Vet Res Commun 35, 55–60 (2011). https://doi.org/10.1007/s11259-010-9448-4

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11259-010-9448-4

Keywords

Search

Navigation