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Evaluation of the muscular relaxant effect of dexmedetomidine or medetomidine in cats

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Abbreviations

DEX:

dexmedetomidine

LEV:

levomedetomidine

MED:

metedomidine

References

  • Aho M., Scheinin M., Lehtinen A.M., Erkola O., Vuorinen J., Korttila K., 1992. Intramuscularly administered dexmedetomidine attenuates hemodynamic and stress hormone responses to gynecologic laparoscopy. Anesthesia and Analgesia, 6, 932–939.

    Google Scholar 

  • Ansah O.B., Raekallio M., Vainio O., 1998. Comparison of three doses of dexmedetomidine with medetomidine in cats following intramuscular administration. Journal of Veterinary Pharmacology and Therapeutics, 5, 380–387.

    Article  Google Scholar 

  • Ansah O.B., Raekallio M., Vainio O., 2000. Correlation between serum concentrations following continuous intravenous infusion of dexmedetomidine or medetomidine in cats and their sedative and analgesic effects. Journal of Veterinary Pharmacology and Therapeutics, 1, 1–8.

    Article  Google Scholar 

  • Cullen L.K., 1996. Medetomidine sedation in dogs and cats: a review of its pharmacology, antagonism and dose. British Veterinary Journal, 5, 519–535.

    Article  Google Scholar 

  • Doze V.A., Chen B.X., Li Z., Maze M., 1989. Pharmacologic characterization of the receptor mediating the hypnotic action of dexmedetomidine. Acta Veterinaria Scandinavica, 85, 61–64.

    PubMed  CAS  Google Scholar 

  • Granholm M., McKusick B.C., Westerholm F.C., Aspegrén J.C., 2006. Evaluation of the clinical efficacy and safety of dexmedetomidine or medetomidine in cats and their reversal with atipamezole. Veterinary Anaesthesia and Analgesia, 4, 214–223.

    Article  Google Scholar 

  • Granholm M., McKusick B.C., Westerholm F.C., Aspegrén J.C., 2007. Evaluation of the clinical efficacy and safety of intramuscular and intravenous doses of dexmedetomidine and medetomidine in dogs and their reversal with atipamezole. Veterinary Record, 26, 891–897.

    Google Scholar 

  • Kuusela E., Raekallio M., Anttila M., Falck I., Mölsä S., Vainio O., 2000. Clinical effects and pharmacokinetics of medetomidine and its enantiomers in dogs. Journal of Veterinary Pharmacology and Therapeutics, 1, 15–20.

    Article  Google Scholar 

  • Kuusela E., Vainio O., Kaistinen A., Kobylin S., Raekallio M., 2001. Sedative, analgesic, and cardiovascular effects of levomedetomidine alone and in combination with dexmedetomidine in dogs. American Journal of Veterinary Research, 4, 616–621.

    Article  Google Scholar 

  • MacDonald E., Scheinin M., Scheinin H., Virtanen R., 1991. Comparison of the behavioral and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha2-adrenoceptor agonist. The Journal of Pharmacology and Experimental Therapeutics, 2, 848–854.

    Google Scholar 

  • Mendes G.M., Selmi A.L., Barbudo-Selmi G.R., Lins B.T., Figueiredo J.P., 2003. Clinical use of dexmedetomidine as premedicant in cats undergoing propofol-sevoflurane anaesthesia. Journal of Feline Medicine and Surgery, 5, 265–270.

    Article  PubMed  CAS  Google Scholar 

  • Savola J.M. and Virtanen R., 1991. Central alpha2-adrenoceptors are highly stereoselective for dexmedetomidine, the dextro enantiomer of medetomidine. European Journal of Pharmacology, 2, 193–199.

    Article  Google Scholar 

  • Schwinn D.A., Correa-Sales C., Page S.O., Maze M., 1991. Functional effects of activation of alpha1-adrenoceptors by dexmedetomidine: in vivo and in vitro studies. The Journal of Pharmacology and Experimental Therapeutics, 3, 1147–1152.

    Google Scholar 

  • Stenberg D., Salvén P., Miettinen M.V., 1987. Sedative action of the alpha2-agonist medetomidine in cats. Journal of Veterinary Pharmacology and Therapeutics, 4, 319–323.

    Article  Google Scholar 

  • Vähä-Vahe T., 1989. Clinical evaluation of medetomidine, a novel sedative and analgesic drug for dogs and cats. Acta Veterinaria Scandinavica, 3, 267–273.

    Google Scholar 

  • Virtanen R., Savola J.M., Saano V., Nyman L., 1988. Characterization of the selectivity, specificity and potency of medetomidine as an alpha2-adrenoceptor agonist. European Journal of Pharmacology, 1–2, 9–14.

    Article  Google Scholar 

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Correspondence to P. Scrollavezza.

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Scrollavezza, P., Tambella, A.M., Vullo, C. et al. Evaluation of the muscular relaxant effect of dexmedetomidine or medetomidine in cats. Vet Res Commun 33 (Suppl 1), 213–215 (2009). https://doi.org/10.1007/s11259-009-9271-y

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  • DOI: https://doi.org/10.1007/s11259-009-9271-y

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