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Mild chronic kidney disease and its relation to functional disability in Korean elderly population

  • Nephrology - Original Paper
  • Published:
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Abstract

Purpose

Studies have demonstrated that chronic kidney disease (CKD) is significantly associated with the increased risk of functional difficulty in daily activity and mobility. However, data are less available for association between CKD and functional disability in Asians.

Methods

Using a data from Korea National Health and Nutrition Examination Survey III, we investigated the association of CKD with functional disability in 882 subjects over the age of 65. Disability was identified in activity of daily living (ADL), instrumental ADL (IADL), and visual, hearing, and walking function. The prevalence of disability was evaluated according to the stage of CKD, and multivariate logistic regression analysis was used to calculate the adjusted odds ratios (ORs) and 95% confidence interval (CI) [adjusted ORs (95% CI)] of CKD stage 3a for disability in ADL, IADL, visual, hearing, and walking function.

Results

Individuals with CKD stage 3–4 had the higher prevalence of disability ADL, IADL, visual, hearing, and walking function than individuals without CKD. CKD stage 3a was significantly associated with abnormal ADL [1.63 (1.04–2.54)] and visual impairment [1.39 (1.01–1.93)] even after adjusting for DM, hypertension, education, income, marital status, age, and sex.

Conclusion

The presence of mild CKD was significantly associated with disability in daily activity and multiple function.

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Funding

This study is supported by a Veterans Health Service Medical Center Research Grant, Republic of Korea (VHSMC18008).

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Authors and Affiliations

  1. Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

    Sung Keun Park

  2. Department of Internal Medicine, Hansol Hospital, Seoul, Republic of Korea

    Won Joong Kim

  3. Department of Environmental Medicine, Inha University Hospital, Incheon, Republic of Korea

    Sang Yoon Lee

  4. Departments of Occupational and Environmental Medicine, School of Medicine, Kyung Hee University, Seoul, Republic of Korea

    Jae-Hong Ryoo

  5. Yonsei Miso Dental Clinic, Seongnam, Republic of Korea

    Kangbaek Lee

  6. Department of Internal Medicine, Veterans Healthcare Service Medical Center, 53, Jinhwangdo-ro 61-gil, Gangdong-gu, Seoul, Republic of Korea

    Dong-Young Lee

Authors
  1. Sung Keun Park
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  2. Won Joong Kim
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  3. Sang Yoon Lee
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  4. Jae-Hong Ryoo
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  5. Kangbaek Lee
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Corresponding author

Correspondence to Dong-Young Lee.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical standards

All protocols were approved by the Institutional review boards of hospitals involved in this study.

Informed consent

Informed consent was obtained from all participant in the study.

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Park, S.K., Kim, W.J., Lee, S.Y. et al. Mild chronic kidney disease and its relation to functional disability in Korean elderly population. Int Urol Nephrol 52, 1929–1934 (2020). https://doi.org/10.1007/s11255-020-02559-y

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  • DOI: https://doi.org/10.1007/s11255-020-02559-y

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