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Perioperative major acute cardiovascular events after 180-W GreenLight laser photoselective vaporization of the prostate

  • Urology - Original Paper
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Abstract

Background

Major acute cardiovascular events (MACE) prevalence after 180-W GreenLight (180-W GL) laser photoselective vaporization (PVP) have never been explored. Aim of our study is to evaluate perioperative MACE that occurred concomitantly with 180-W GL PVP.

Materials and methods

We relied on a multi-institutional database that included 14 centers. Data from 923 patients who underwent 180-W GL PVP were reviewed. We abstracted pre- and perioperative data of patients who experienced perioperative MACE, such as angina pectoris, acute myocardial infarction, other chronic ischemic heart disease, transient ischemic attack, or cerebrovascular accident as well as deep venous thrombosis with or without pulmonary embolism. We relied on a case-series format to report the main findings of our analyses.

Results

18 (1.9%) patients reported MACE in 7 centers. Median age was 69.5 (IQR 66.0–79.2) years. Of all, 7 patients underwent standard PVP and 11 anatomical PVP. Eleven patients (61.1%) were not under anticoagulant/antiplatelet treatment, 6 (33.3%) were under low dose aspirin, and 1 (5.6%) was under clopidogrel. Four patients (22.2%) had an instrumental and laboratory diagnosis of myocardial infarction, 7 (38.9%) had an episode of angina pectoris with or without rhythm alteration, 3 (16.7%) reported symptomatic deep venous thrombosis, and 4 (22.2%) had other MACE-like events.

Conclusions

Physician should take in consideration the possibility of MACE or MACE-like events. The real MACE rate may be different as only half of included centers reported MACE. Since the main target of laser surgery are high-risk bleeding patients, prospective observational trials focused on detection of these possible complications are warranted.

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Author information

Authors and Affiliations

  1. Department of Urology, “G. D’Annunzio” University, Chieti, Italy

    Michele Marchioni & Luigi Schips

  2. Department of Urology, Humanitas Gavazzeni Hospital, Bergamo, Italy

    Francesco Greco

  3. Department of Urology, “Ercole Franchini” Hospital, Montecchio Emilia and Civital Hospital of Guastalla, AUSL of Reggio Emilia, Reggio Emilia, Italy

    Antonio Frattini

  4. Department of Urology, ASL Abruzzo2, Chieti, Italy

    Fabio Neri & Luca Cindolo

  5. Department of Urology, Clinica urologica azienda ospedaliera - University of Padova, Padua, Italy

    Lorenzo Ruggera

  6. Department of Urology, “S. Lazzaro” Hospital, Alba, Italy

    Giuseppe Fasolis & Francesco Varvello

  7. Department of Urology, Azienda Ospedaliera Città della Salute e della Scienza di Torino – Sede Molinette, Torino, Italy

    Paolo Destefanis

  8. Department of Emergency and Organ Transplantation, Urology and Andrology Unit II, University of Bari, Bari, Italy

    Gaetano De Rienzo & Pasquale Ditonno

  9. Department of Urology, “Hesperia” Hospital, Modena, Italy

    Giovanni Ferrari

  10. Urology Department, ASL Abruzzo2, Via S. Camillo de Lellis 1, 66054, Vasto, Italy

    Luca Cindolo

Authors
  1. Michele Marchioni
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  2. Luigi Schips
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  3. Francesco Greco
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  4. Antonio Frattini
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  5. Fabio Neri
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  6. Lorenzo Ruggera
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  7. Giuseppe Fasolis
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  8. Francesco Varvello
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  9. Paolo Destefanis
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  10. Gaetano De Rienzo
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  11. Pasquale Ditonno
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  12. Giovanni Ferrari
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  13. Luca Cindolo
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Contributions

MM, LC, FG: Project development, Data analysis, Manuscript writing. All the authors: Data collection. LS, LC, GF: Supervision. All the authors: Project development, Manuscript editing.

Corresponding author

Correspondence to Luca Cindolo.

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Conflict of interest

LC, LR, PD, GF do surgical tutorship for AMS and received honoraria for their tutorship.

Ethical approval

For this type of study, formal consent is not required.

Informed consent

Informed consent was obtained from all individual participants included in the study. This study and all the related procedures have been performed in accordance with the Declaration of Helsinki.

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Marchioni, M., Schips, L., Greco, F. et al. Perioperative major acute cardiovascular events after 180-W GreenLight laser photoselective vaporization of the prostate. Int Urol Nephrol 50, 1955–1962 (2018). https://doi.org/10.1007/s11255-018-1968-9

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  • DOI: https://doi.org/10.1007/s11255-018-1968-9

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