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An ignored cause of inflammation in patients undergoing continuous ambulatory peritoneal dialysis: periodontal problems

  • Nephrology - Original Paper
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Abstract

Aim

We aimed to assess whether there is a significant relation between periodontal health status and inflammation in uremic patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and also to reveal the efficiency of periodontal treatment in patients with various degrees of periodontal problems.

Patients and methods

Overall, 68 patients undergoing CAPD were included in the study. Clinical indices and measurements were obtained at baseline and panoramic radiographies were used for the diagnosis. According to the baseline values, patients were stratified into four groups according to the severity of periodontal problems as follows: healthy/gingivitis, slight-to-moderate, and severe periodontitis. A control examination was performed 3 months after the periodontal treatment for only 43 patients. Clinical and laboratory parameters before and after treatment were compared.

Results

The frequency of periodontal disease was found to be high in uremic patients on CAPD. The frequency and severity of periodontitis was also found to be significantly (p < 0.01) higher in patients with high sensitive C-reactive protein levels and longer duration of peritoneal dialysis (p < 0.01). In addition, the periodontitis rate was found to be higher in patients with cardiovascular disease (p < 0.05) and diabetes mellitus (p < 0.01).

Conclusion

A meticulous periodontal examination should be a routine part of management of the uremic patients on CAPD because periodontal disease could be one of the hidden sources of unexplained inflammatory status.

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Authors and Affiliations

  1. Department of Nephrology, Erciyes University Medical Faculty, 38039, Kayseri, Turkey

    Ismail Kocyigit, Aydin Unal, Murat Hayri Sipahioglu, Oktay Oymak & Bulent Tokgoz

  2. Department of Internal Medicine, Erciyes University Medical Faculty, Kayseri, Turkey

    Hasan Esat Yucel & Hafsa Korkar

  3. Department of Periodontology, Erciyes University Faculty of Dentistry, Kayseri, Turkey

    Omer Cakmak, Dürdane Banu Durukan & Cem A. Gurgan

  4. Department of Internal Medicine, Erciyes University Faculty of Dentistry, Kayseri, Turkey

    Fatma Dogruel

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  1. Ismail Kocyigit
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  2. Hasan Esat Yucel
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Correspondence to Ismail Kocyigit.

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Kocyigit, I., Yucel, H.E., Cakmak, O. et al. An ignored cause of inflammation in patients undergoing continuous ambulatory peritoneal dialysis: periodontal problems. Int Urol Nephrol 46, 2021–2028 (2014). https://doi.org/10.1007/s11255-014-0716-z

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  • DOI: https://doi.org/10.1007/s11255-014-0716-z

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