Skip to main content
SpringerLink
Log in

Local ethanol injection for the treatment of deltoid parathyroid cell hyperplasia

  • Nephrology - Case Report
  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

Secondary hyperparathyroidism (SHPT) is a serious complication in dialysis patients and is routinely managed with medical therapy. Refractory disease is usually treated either surgically or by local ethanol injection into the parathyroid glands. Total parathyroidectomy with deltoid implant can be successful; however, recurrent, resistant disease is not uncommon. Local ethanol injection was applied to the deltoid autoimplant of a patient with recurrent, resistant SHPT, which had not been resolved with surgical treatment. Serum intact parathyroid hormone (iPTH) levels subsequently decreased from 1,400 to 219 pg/dl and remained stable for the next 6 months. To our knowledge, this procedure has not been previously described in the literature. Local injection of ethanol may represent an interesting alternative to surgery for the treatment of deltoid parathyroid cell hyperplasia in patients in which surgical treatment is not an option.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Polu K, Singh A (2006) Pathogenesis and management of secondary hyperparathyroidism. In: Hsu C (ed) Calcium and phosphate metabolism management in chronic renal disease. Springer, Michigan, pp 29–70

    Google Scholar 

  2. Clarkson M, Magee C, Brenner B (2010) Disorders of calcium, magnesium, and phosphate balance in the kidney. Saunders, Philadelphia, pp 166–185

    Google Scholar 

  3. Douthat WG, Orozco SE, de Arteaga J, Massari PU (2003) Treatment of refractory secondary hyperparathyroidism with ethanol injection: the importance of glandular volume. Kidney Int Suppl 85:S101–S104

    Article  PubMed  Google Scholar 

  4. Chen HH, Lin CJ, Wu CJ, Lai CT, Lin J, Cheng SP, Yang TL (2011) Chemical ablation of recurrent and persistent secondary hyperparathyroidism after subtotal parathyroidectomy. Ann Surg 253(4):786–790

    Article  PubMed  Google Scholar 

  5. Fassi J, Lambertini R, Farias P, Blejman O, Rosa Diez G, Algranati S, Plantalech L (2005) Treatment of uremic hyperparathyroidism with percutaneous ethanol injection. Nephron Clin Pract 101(2):c53–c57

    Article  CAS  PubMed  Google Scholar 

  6. Iovino F, Armano G, Auriemma PP, Sergio R, De Sena G, Capuozzo V, Rosso F, Marino G, Papale F, Grimaldi A, Barbarisi A (2010) Tissue engineering of parathyroid gland. G Chir 31(6–7):312–315

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. General Surgery Division, Education and Research Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    M. Figari

  2. Nephrology Division, Education and Research Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    C. G. Musso

  3. Endocrinology Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    L. Plantalech & A. Mollerach

  4. Education and Research Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    R. Lambertini

  5. Nephrology Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    H. Rivera

Authors
  1. M. Figari
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. G. Musso
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. Plantalech
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. Lambertini
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. H. Rivera
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. Mollerach
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to C. G. Musso.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Figari, M., Musso, C.G., Plantalech, L. et al. Local ethanol injection for the treatment of deltoid parathyroid cell hyperplasia. Int Urol Nephrol 46, 247–249 (2014). https://doi.org/10.1007/s11255-012-0372-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11255-012-0372-0

Keywords

Search

Navigation