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Juxtaglomerular cell tumor, causing fetal demise

  • Urology – Case Report
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International Urology and Nephrology Aims and scope Submit manuscript

Abstract

Aims

This case report describes juxtaglomerular cell tumor—a rare renin-producing tumor of the kidney, complicating pregnancy.

Clinical case

A previously healthy 24-year-old primigravid woman developed hypertension in the 20th week of pregnancy, leading to a miscarriage in the 28th week. However, hypertension continued after the miscarriage. A more complete examination revealed a solid tumor in the lower pole of the right kidney. The patient underwent a partial right nephrectomy. A histological examination and electron microscopy confirmed the diagnosis of JGCT. The patient´s blood pressure was normalized within 2 weeks.

Conclusions

JGCT can lead to miscarriage if undiscovered during pregnancy. A kidney ultrasound should be performed on pregnant women with newly detected hypertension. No staining in early phase of contrast CT is the feature that differentiates JGCT from renal cell carcinoma. These tumors are benign, with only one reported exception, and nephron-sparing surgery is preferable.

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Acknowledgments

Mr. Jonathan Guss is greatly acknowledged for help with the manuscript.

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Authors and Affiliations

  1. Department of Urology, Faculty Hospital, Trieda SNP 1, 040 11, Kosice, Slovakia

    Lubomir Lachvac, Marian Svajdler, Ladislav Valansky, Vincent Nagy, Marian Benicky, Lucia Frohlichova & Olga Nyitrayova

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  1. Lubomir Lachvac
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  2. Marian Svajdler
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  3. Ladislav Valansky
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  4. Vincent Nagy
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  5. Marian Benicky
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  6. Lucia Frohlichova
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  7. Olga Nyitrayova
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Correspondence to Lubomir Lachvac.

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Lachvac, L., Svajdler, M., Valansky, L. et al. Juxtaglomerular cell tumor, causing fetal demise. Int Urol Nephrol 43, 365–370 (2011). https://doi.org/10.1007/s11255-010-9782-z

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  • DOI: https://doi.org/10.1007/s11255-010-9782-z

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