Abstract
Brucella glomerulonephritis is a rare condition with only a few reported cases. We review the literature, and describe a 24-year-old female who presented with edema and proteinuria. Blood grew Brucella melitensis. Renal biopsy showed diffuse proliferative glomerulonephritis. The patient progressed to end-stage renal disease despite antibiotic and steroid therapy.
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References
Dunea G, Kark RM, Lannigan R, D’Alessio D, Muehrcke RC (1969) Brucella nephritis. Ann Intern Med 70:783–790
Colmenero JD, Munoz-Roca NL, Bermudez P, Plata A, Villalobos A, Reguera JM (2007) Clinical findings, diagnostic approach, and outcome of Brucella melitensis epididymo-orchitis. Diagn Microbiol Infect Dis 57:367–372
Sahin I, Arabaci F, Eminbeyli L, Ilhan M, Onbasi K, Avni Sahin H (2005) Renal involvement in brucellosis. Nephrol Dial Transplant 20(Suppl 5):288
Petereit MF. Chronic renal brucellosis: a simulator of tuberculosis (1970) Case report. Radiology 96:85–86
Onaran M, Sen I, Polat F, Irkilata L, Tunc L, Biri H (2005) Renal brucelloma: a rare infection of the kidney. Int J Urol 12:1058–1060
Nunan TO, Eykyn SJ, Jones NF (1984) Brucellosis with mesangial IgA nephropathy: successful treatment with doxycycline and rifampicin. Br Med J 288:1802
Doregatti C, Volpi A, Torri Tarelli L et al (1985) Acute glomerulonephritis in human brucellosis. Nephron 41:365–366
Abu Romeh SH, Kozma GN, Johny KV, Sabha M (1987) Brucella endocarditis causing acute renal failure. Nephron 46:388–389
Eugene M, Gauvain JB, Roux C, Barthez JP (1987) A case of acute brucellosis with membranous glomerulopathy. Clin Nephrol 28:158–159
Siegelmann N, Abraham AS, Rudensky B, Shemesh O (1992) Brucellosis with nephrotic syndrome, nephritis and IgA nephropathy. Postgrad Med J 68:834–836
Haririan A, Ghadiri G, Broumand B (1993) Brucella glomerulonephritis. Nephrol Dial Transplant 8:373–374
Elzouki AY, Akthar M, Mirza K (1996) Brucella endocarditis associated with glomerulonephritis and renal vasculitis. Pediatr Nephrol 10:748–751
Altiparmak MR, Pamuk GE, Pamuk ON, Tabak F (2002) Brucella glomerulonephritis: review of the literature and report on the first patient with brucellosis and mesangiocapillary glomerulonephritis. Scand J Infect Dis 34:477–480
Ustun I, Ozcakar L, Arda N et al (2005) Brucella glomerulonephritis: case report and review of the literature. South Med J 98:1216–1217
Ardalan MR, Shoja MM (2006) Rapidly progressive glomerulonephritis in a patient with brucellosis. Nephrol Dial Transplant 21:1743–1744
Kusztal M, Dorobisz A, Kuzniar J et al (2007) Dissecting aneurysm of the thoracic aorta in a patient with nephritic syndrome and brucellosis. Int Urol Nephrol 39:641–645
Bruijn JA (2006) Postinfectious Glomerulonephritis. In: Fugo AB, Bruijn JA, Cohen AH, Colvin RB, Jennettte JC (eds) Fundamentals of renal pathology, Springer, New York pp 55–60
Moroni G, Pozzi C, Quaglini S et al (2002) Long term prognosis of diffuse proliferative glomerulonephritis associated with infection in adults. Nephrol Dial Transplant 17:1204–1211
Muthukumar T, Jayakumar M, Fernando EM, Muthusethupathi MA (2002) Acute renal failure due to rifampicin: a study of 25 patients. Am J Kidney Dis 40:690–696
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None of the authors has a conflict of interest regarding this case report. No funding was available.
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Bakri, F.G., Wahbeh, A., Mahafzah, A. et al. Brucella glomerulonephritis resulting in end-stage renal disease: a case report and a brief review of the literature. Int Urol Nephrol 40, 529–533 (2008). https://doi.org/10.1007/s11255-007-9311-x
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DOI: https://doi.org/10.1007/s11255-007-9311-x