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Stress amelioration potential of vitamin C in ruminants: a review

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Abstract

Ruminants, as well as other livestock, can synthesize vitamin C (VC) in their liver, and therefore, dietary requirements from exogenous supplementation are often ignored. However, metabolic demand may be exceeded, leading to a decreased endogenous synthetic capacity of VC following exposure to stressful conditions. Such conditions include high thermal load, limited water intake (induced by water scarcity), physiological status and infectious diseases. The obvious consequences are decreased performance, susceptibility to infections and increased mortality. This review discusses the potential role of vitamin C in ruminants’ stress management and summarizes the in vitro and in vivo research to date. The different administration routes, comparative advantages and supplementation outcomes on growth, production parameters and physiological status were also identified. Also, areas where there was a lack of evidence or controversy, including critical literature research gaps, were identified, while the mechanism of VC’s actions on significant outcomes was explained.

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Acknowledgements

The author wants to appreciate the contribution of my main supervisor, late Prof. Voster Muchenje. This review was part of the research funded by the National Research Foundation/The World Academy of Science (Grant number 110851).

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Authors and Affiliations

  1. Department of Livestock and Pasture Science, Faculty of Science and Agriculture, University of Fort Hare, Private Bag X1314Eastern Cape, Alice, 5700, South Africa

    Oluwakamisi Festus Akinmoladun

  2. Department of Animal and Environmental Biology, Faculty of Science, Adekunle Ajasin University, PMB 001, Akungba-Akoko, Ondo-State, Nigeria

    Oluwakamisi Festus Akinmoladun

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  1. Oluwakamisi Festus Akinmoladun
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Correspondence to Oluwakamisi Festus Akinmoladun.

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Akinmoladun, O.F. Stress amelioration potential of vitamin C in ruminants: a review. Trop Anim Health Prod 54, 24 (2022). https://doi.org/10.1007/s11250-021-03026-1

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