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Effects of dietary Mitracarpus scaber leaves extract on growth, physiological, antioxidants, and mucosal immune profiles of North African catfish, Clarias gariepinus, and resistance against Edwardsiella tarda infection

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Abstract

This study evaluated the effect of Mitracarpus scaber leaves extract (MSLE) as a dietary supplement on growth performance, physiological, antioxidants, and mucosal immune profiles of North African catfish, Clarias gariepinus, and resistance to Edwardsiella tarda infection. Four isonitrogenous diets containing 0, 2, 4, or 6 MSLE g/kg were fed to North African catfish fingerlings (n = 240; mean weight = 5.80 g) for 56 days. After the feeding trial, 10 fish from each experimental tank were intraperitoneally injected with E. tarda (ATCC 15,947; 1.0 × 108 CFU/mL) while clinical signs and mortalities were observed for 14 days. The results show that North African catfish fed dietary MSLE had better growth performance, physiological antioxidants, and mucosal immune profiles than when fed a control diet. The best growth, physiological, antioxidant, and mucosal immune response profiles were noticed in the fish fed diet containing 6 MSLE g/kg. Furthermore, fish fed 6 MSLE g/kg diet had a higher survival rate after E. tarda infection. These results indicated that supplementation of MSLE at 6 g/kg improves growth, physiological, antioxidant, and mucosal immune profiles, and promotes resistance of North African catfish.

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The data sets generated during and or analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

Our special thanks go to the technologists in the Department of Aquaculture and Fisheries for their support.

Funding

The research leading to these results received funding from University of Ilorin, Ilorin Nigeria under Staff Development Award (SDA 2015). Our special thanks go to Mr. Ogundayomi who provided the fund for this study.

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Authors and Affiliations

  1. Department of Aquaculture and Fisheries, University of Ilorin, Ilorin, Kwara State, Nigeria

    Ibrahim Adeshina, Lateef O. Tiamiyu, Musa I. Abubakar & Oluwafunmike O. Ogundayomi

  2. Department of Agricultural Education, Kwara State College of Education, Ilorin, Kwara State, Nigeria

    Ojo Adesanmi

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  1. Ibrahim Adeshina
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  2. Lateef O. Tiamiyu
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  3. Musa I. Abubakar
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  4. Oluwafunmike O. Ogundayomi
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Contributions

Ibrahim Adeshina: drafted paper; Lateef O. Tiamiyu: manuscript revision; Musa I. Abubakar: biochemical analysis; Oluwafunmike O. Ogundayomi: experimental test, statistical analysis; Ojo Adesanmi: laboratory analysis.

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Correspondence to Ibrahim Adeshina.

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All procedures involving animals were in compliance with the European Community Council Direcitve of 24 November 1986, and ethical approval was granted by University Ethics Committee on Animal Care Use and Research University of Ibadan (ACUREC-UI-2017–19).

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Adeshina, I., Tiamiyu, L.O., Abubakar, M.I. et al. Effects of dietary Mitracarpus scaber leaves extract on growth, physiological, antioxidants, and mucosal immune profiles of North African catfish, Clarias gariepinus, and resistance against Edwardsiella tarda infection. Trop Anim Health Prod 53, 541 (2021). https://doi.org/10.1007/s11250-021-02989-5

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