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Condensed tannins from Sesbania sesban and Desmodium intortum as a means of Haemonchus contortus control in goats

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Abstract

Two experiments were conducted to determine whether the proanthocyanidin (condensed tannin)-containing forage legumes Desmodium intortum cv Greenleaf and Sesbania sesban (accession 15019) could be integrated into a feeding management strategy as a means of Haemonchus contortus control in goats. The anthelmintic effects of condensed tannin extracts from the two legumes on H. contortus L3 larvae were studied in an in vitro larval migration inhibition system. The extracts inhibited larval migration in a dose-dependent manner, and at concentrations from 1,000 μg/ml condensed tannin, the extract from D. intortum caused a significantly higher inhibition of larval migration than did the corresponding concentrations of the S. sesban extract (P < 0.01). Prolonged feeding of tanniniferous forage legumes showed that animals receiving D. intortum had the lowest total worm burden, the lowest female to male parasite ratio, the lowest number of eggs in the uterus of each female worm and the lowest per capita fecundity (P < 0.01). However, there was no change in the performance (weight gain) of parasite-infected goats probably due to incomplete removal of the parasite or prolonged confinement of goats in small pens, which calls for further investigation. However, since there is no single efficient method in control of parasites, based on the obtained data from this experiment, integrated feeding of D. intortum with other suitable method of parasite control is thus suggested.

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References

  • Aerts, R.J., Barry, T.N., McNabb, W.C., 1999. Polyphenols and agriculture: beneficial effects of proanthocyanidins in forages. Agriculture, Ecosystem and Environment 75, 1–12.

    Article  CAS  Google Scholar 

  • Athanasiadou, S., Kyriazakis, I., Jackson, F., Coop, R.L., 2000. Consequences of long term feeding with condensed tannins on sheep parasitized with Trichostrogulus colubriforimis. Journal of Parasitology 30, 1025–1033.

    CAS  Google Scholar 

  • Athanasiadou, S., Kyriazakis, I., Jackson, F., Coop, R.L., 2001. Direct anthelmintic effect of condensed tannins towards different gastrointestinal nematodes of sheep: in vitro and in vivo studies. Veterinary Parasitology 99, 205–219.

    Article  PubMed  CAS  Google Scholar 

  • Ben Salem, H., Nefzaoui, A., Ben Salem, L., Tisserand, J.L., 1999. Intake, digestibility, urinary excretion of purine derivatives and growth by sheep given fresh, air-dried or polyethylene glycol-treated foliage of Acacia cyanophylla Lindl. Animal Feed Science and Technology 78, 297–311.

    Article  CAS  Google Scholar 

  • Brunet, S., Hoste, H., 2006. Monomers of condensed tannins affect the larval ex-sheathment of parasitic nematodes of ruminants. Journal of Agriculture and Food Chemistry 54, 7481–7487.

    Article  CAS  Google Scholar 

  • Butter, N. L., Dawson, J. M., Wakelin, D.Butter, P.J., 2001. Effect of dietary condensed tannins on gastrointestinal nematodes. Journal of Agricultural Science 137, 461–469.

    CAS  Google Scholar 

  • Debela, E., 2002. Epidemiology of gastrointestinal helminthiasis of Rift valley goats under traditional husbandry system in Adami Tulu District, Ethiopia. SINET: Ethiopian Journal of Science 25, 35–44.

    Article  Google Scholar 

  • Eguale, T., Tilahun, G., Debella, A., Feleke, A., Makonnen, E., 2007. Haemonchus contortus: In vitro and in vivo anthelmintic activity of aqueous and hydro-alcoholic extracts of Hedera helix. Experimental Parasitology 116, 340–345.

    Article  PubMed  CAS  Google Scholar 

  • Hansen, J., Perry, B., 1994. The epidemiology, diagnosis and control of helminth parasites of ruminants: A handbook. International Livestock Research Institute, Nairobi, 171 pp.

    Google Scholar 

  • Heckendorn, F., Häring, D.A., Maurer, V., Zinsstag, J., Langhans, W., Hertzberg, H., 2006. Effect of sainfoin (Onobrychis viciifolia) silage and hay on established populations of Haemonchus contortus and Cooperia curticei in lambs. Veterinary Parasitology 142, 293–300.

    Article  PubMed  Google Scholar 

  • Heckendorn, F., Häring, D.A., Maurer, V., Senn, M., Hertzberg, H., 2008. Individual administration of three tanniferous forage plants to lambs artificially infected with Haemonchus contortus and Cooperia curticei. Veterinary Parasitology 146, 123–134.

    Article  Google Scholar 

  • Hoskin, S.O., Wilson, P.R. Barry, T.N. Charleston, W.A.G., Waghorn, G.C., 2000. Effect of forage legumes containing condensed tannins on lungworm (Dictyocaulus sp.) and gastrointestinal parasitism in young red deer (Cervus elaphus). Research in Veterinary Science 68, 223–230.

    Article  PubMed  CAS  Google Scholar 

  • Hoste, H., Torres-Ascota, J.F., Paolini, V., Anguilar-Caballero, A., Etter, E., Lefrileux, Y., Chartier, C., Broqua, C., 2005. Interactions between nutrition and gastrointestinal infections with parasitic nematodes in goats. Small Ruminant Research 60, 141–151.

    Article  Google Scholar 

  • Jackson, F.S., McNabb, W.C., Barry, T.N., Foo, Y.L., Peters, J.S., 1996. The condensed tannins of a range of subtropical and temperate forages and the activity of condensed tannin with ribose-1, 5-biphosphate carboxylase (Rubisco) protein. Journal of the Science of Food and Agriculture 72, 483–492.

    Article  CAS  Google Scholar 

  • Kabasa, J.D., Opuda-Asibo, J., ter Meulen, U., 2000. The effect of oral administration of polyethylene glycol on faecal helminth egg counts in pregnant goats grazed on browse containing condensed tannins. Tropical Animal Health and Production 32, 73–86.

    Article  PubMed  CAS  Google Scholar 

  • Kahiya, C., Mukaratira, S., Thamsborg, S.M., 2003. Effects of Acacia nilotica and Acacia karoo diets on Haemonchus contortus infections in goats. Veterinary Parasitology 115, 265–274.

    Article  PubMed  CAS  Google Scholar 

  • Kearl, L.C., 1982. Nutrient Requirements of Ruminants in Developing Countries. International Feedstuffs Institute, Utah State University, Logan, UT, 381 pp.

    Google Scholar 

  • Kumsa, B., Abebe, G., 2009. Multiple anthelmintic resistances on a goat farm in Hawassa (Southern Ethiopia). Tropical Animal Health and Production 41, 655–662.

    Article  PubMed  Google Scholar 

  • Landau, S., Azaizeh, H., Muklada, H., Glasser, T., Ungar, E.D., Baram, H., Abbas, N., Markoviccs, A., 2010. Anthelmintic activity of Pistacia lentiscus foliage in two Middle Eastern breeds of goats differing in their propensity to consume tannin-rich browse. Veterinary Parasitology 173, 280–286.

    Article  PubMed  CAS  Google Scholar 

  • Makkar, H.P.S., 1993. Antinutritional factors in foods of livestock. In: Gill, M, Owen, E, Pollot, G.E., Lawrence, T.L.J., (eds), Animal Production in Developing Countries, Occasional Publication No. 16, pp. 69–85.

  • Max, R.A., 2010. Effect of repeated wattle tannin drenches on worm burdens, faecal egg counts and egg hatchability during naturally acquired nematode infections in sheep and goats. Veterinary Parasitology 169, 138–143.

    Article  PubMed  CAS  Google Scholar 

  • Max, R.A., Kimambo, A.E., Kassuku, A.A., Mtenga, L.A., Buttery, P.J., 2007. Effect of tanniniferous browse meal on nematode faecal egg counts and internal parasite burdens in sheep and goats. Journal of Agricultural Science 37, 97–106.

    Google Scholar 

  • Max, R.A., Kassuku, A.A., Kimambo, A.E., Mtenga, L.A., Wakelin, D., Buttery, P.J., 2009. The effects of wattle tannin drenches on gastrointestinal nematodes of tropical sheep and goats during experimental and natural infections. Journal of Agricultural Science 147, 211–218.

    Article  CAS  Google Scholar 

  • Molan, A.L, Waghorn, G.C., Min, BR., McNabb, WC., 2000. The effect of condensed tannins from seven herbages on Trichostrogylus colubriformis larval migration in-vitro. Folia Parasitologica 47, 39–44.

    PubMed  CAS  Google Scholar 

  • Molan, A.L, Waghorn, G.C., Min, BR, McNabb, W.C., 2002. Effect of condensed tannins on egg hatching and larval development of Trichstrongylus colubriformis in vitro. Veterinary Record 150, 65–69.

    Article  PubMed  CAS  Google Scholar 

  • Molan, A.L., Duncan, A. J., Barry, T. N., McNabb, W.C., 2003. Effects of condensed tannins and crude sesquiterpene lactones extracted from Chicory on the motility of larvae of deer lungworm and gastrointestinal nematodes. Parasitology International 52, 209–218.

    Article  PubMed  CAS  Google Scholar 

  • Mueller-Harvey, I., 2006. Review. Unravelling the conundrum of tannins in animal nutrition and health. Journal of the Science of food and Agriculture 86, 2010–2037.

    Article  CAS  Google Scholar 

  • Niezen, J. H., Waghorn, T.S., Waghorn, G.C., Charleston, W.A.G., 1993. Internal parasites and lamb production—a role of plants containing condensed tannins? Proceedings of the New Zealand Society of Animal Production 53, 235–238.

    Google Scholar 

  • Niezen, J.H., Robertson, H.A., Waghorn, G.C., Charleston, W.A. G., 1998a. Production, faecal egg counts and worm burdens of ewe lambs which grazed six contrasting forages. Veterinary Parasitology 80, 15–27.

    Article  PubMed  CAS  Google Scholar 

  • Niezen, J.H., Waghorn, G.C., Charleston, W.A. G.1998b. Establishment and fecundity of Ostertagia circumcincta and Trichostrongylus colubriformis in lambs fed lotus (Lotus pedunculatus) or perennial ryegrass (Lolium perenne). Veterinary Parasitology 78, 13–21.

    Article  PubMed  CAS  Google Scholar 

  • Paolini, V., Bergeaud, J.P., Grisez, C., Prevot, F., Dorchies, P.H., Hoste, H., 2003. Effects of condensed tannins on goats experimentally infected with Haemonchus contortus.Veterinary Parasitology 113, 253–261.

    Article  PubMed  CAS  Google Scholar 

  • Perry, B., Randolph, T., McDermott, J., Sones, K., Tornton, P.K., 2002. Investing in animal health research to alleviate poverty. International Livestock Research Institute, Nairobi, Kenya, 148 pp.

    Google Scholar 

  • Rabel, B, McGregor, R., Douch, P.G.C., 1994. Improved bioassay for estimation of inhibitory effects of bovine gastrointestinal mucus and anthelmintics on nematode larval migration. International Journal for Parasitology 24, 671–676.

    Article  PubMed  CAS  Google Scholar 

  • Robertson, H.A., Niezen, J.H., Waghorn, G.C., Charleston, W.A.G., Jinlong, M. 1995. The effect of six herbages on live weight gain, wool growth and faecal egg count of parasitized ewe lambs. Proceedings of the New Zealand Society of Animal Production 55, 199–201.

    Google Scholar 

  • SAS, 2001: SAS User’s Guide, SAS Institute Inc., Cary, NC, USA.

    Google Scholar 

  • Shaik, S.A., Terrill, T.H., Miller, J.E., Kouakou, B., Kannan, G., Kaplan, R.M., Bruke, J.M., Mosjidid, J.A., 2006. Sericea lespedeza hay as a natural deworming agent against gastrointestinal nematode infections in goats. Veterinary Parasitology 139, 150–157.

    Article  PubMed  CAS  Google Scholar 

  • Terrill, T.H., Waghorn, G.C., Woodley, D.J., McNabb, W.C., Barry, T.N., 1994. Assay and digestion of 14 C-labelled condensed tannin in the gastrointestinal tract of sheep. British Journal of Nutrition 72, 467–477.

    Article  PubMed  CAS  Google Scholar 

  • Terrill, T.H., Dykes, G.S., Shaik, S.A., Miller, J.E., Kouakou, B., Kannan, G., Bruke, J.M., Mosjidis, J.A., 2009. Efficacy of Sericea lespedeza hay as a natural dewormer in goats: dose titration study: Veterinary Parasitology 163, 52–56.

    Article  PubMed  CAS  Google Scholar 

  • Wagland, BM, Jones, W.O., Hribar, L., Bendixen, T., Emery, D.L, 1992. A new simplified assay for larval migration inhibition. International Journal for Parasitology 22, 1183–1185.

    Article  PubMed  CAS  Google Scholar 

  • Waller, P.J., 1997. Nematode parasite control of livestock in the tropics/subtropics: The need for novel approaches. International Journal for Parasitology 27, 488–494.

    Article  Google Scholar 

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Acknowledgments

The authors would like to thank Norwegian Agency for Development Cooperation for financial support.

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Authors and Affiliations

  1. Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, P.O. Box 5300, 1432, Ås, Norway

    Etana Debela, Lars Olav Eik & Ragnar Salte

  2. School of Veterinary Medicine, Hawassa University, P.O. Box 5, Hawassa, Ethiopia

    Etana Debela

  3. Department of Animal and Range Sciences, College of Agriculture, Hawassa University, P.O. Box 5, Hawassa, Ethiopia

    Adugna Tolera

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  1. Etana Debela
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  2. Adugna Tolera
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Correspondence to Etana Debela.

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Debela, E., Tolera, A., Eik, L.O. et al. Condensed tannins from Sesbania sesban and Desmodium intortum as a means of Haemonchus contortus control in goats. Trop Anim Health Prod 44, 1939–1944 (2012). https://doi.org/10.1007/s11250-012-0160-y

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