Abstract
New complexes of Cu(II), Zn(II) and Ni(II) with naringenin have been synthesized and characterized on the basis of elemental analyses, molar conductivities, 1H-n.m.r., i.r. spectra, u.v. spectra, thermal analyses, and fluorescence spectra. In addition, the suppression ratio for O −2 · (a) and OH· (b) of the complexes were studied by spectrophotometric methods. The results show that the effect of the Cu(II)-complex IC50 (a) = 0.003 μm, IC50 (b) = 0.06 μm is the most remarkable, and the average scavenger ability of the complexes (IC50=0.06–2.67μm) against OH· is higher than that of the ligand (IC50 = 28.5 μm). Taken together, these results indicate that the scavenger effect can be enhanced by the formation of metal-ligand coordination complexes, and the transition-metal ions may have differential and selective roles.
Similar content being viewed by others
References
D. Harman (1956) J. Gerontol. 11 298 Occurrence Handle1:STN:280:CymD1cvotlU%3D
B.N. Ames M.K. Shigenaga T.M. Hagen (1993) Proc. Natl. Acad. Sci. USA 90 7915 Occurrence Handle1:CAS:528:DyaK3sXmtVSksL4%3D
B. Halliwell J.M.C. Gutteridge C.E. Cross (1992) J. Lab. Clin. Med. 119 598 Occurrence Handle1:CAS:528:DyaK38Xlt1yqt74%3D
A.A. Horton S. Fairhurst (1987) Crit. Rev. Toxicol. 18 27 Occurrence Handle1:CAS:528:DyaL1cXhs1Wi
S.F. Lo V. Mulabagal C.L. Chen C.L. Kuo H.S. Tsay (2004) J. Agric. Food Chem. 52 6916 Occurrence Handle10.1021/jf040017r Occurrence Handle1:CAS:528:DC%2BD2cXosVOkt78%3D
F. Cheng Breen Kevin (2000) Bio Metals 13 77 Occurrence Handle1:CAS:528:DC%2BD3cXjsFamt7Y%3D
Y.M. Song J.W. Kang Z.H. Wang X.O. Lu J.Z. Guo L.F. Wang (2002) J. Inorg. Biochem. 91 470 Occurrence Handle10.1016/S0162-0134(02)00425-7 Occurrence Handle1:CAS:528:DC%2BD38XmtlCmur0%3D
J. Zhou L.F. Wang N. Tang (2001) J. Inorg. Biochem. 83 41 Occurrence Handle10.1016/S0162-0134(00)00128-8 Occurrence Handle1:CAS:528:DC%2BD3MXoslymug%3D%3D
A.S. Ramaswamy S. Jayaraman M. Sirsi K.H. Rao (1972) Indian J. Exp. Biol. 1 72
C.C. Winterbourn (1979) Biochem. J. 182 625 Occurrence Handle1:CAS:528:DyaL3cXltlOmtw%3D%3D
C.C. Winterbourn (1981) Biochem. J. 198 125 Occurrence Handle1:CAS:528:DyaL3MXmtFKntro%3D
W.J. Geary (1971) Coord. Chem. Rev. 7 81 Occurrence Handle10.1016/S0010-8545(00)80009-0 Occurrence Handle1:CAS:528:DyaE3MXlsVCgsrg%3D
Y.B. Zeng N. Yang W.S. Liu N. Tang (2003) J. Inorg. Biochem. 97 262 Occurrence Handle10.1016/S0162-0134(03)00313-1
Z.Y. Yang R.D. Yang Q. Li F.S. Li (1999) Synth. React. Inorg. Met-Org. Chem. 29 205 Occurrence Handle1:CAS:528:DyaK1MXhtlyjtbc%3D
Z.Y. Yang (2002) Synth. React. Inorg. Met-Org. Chem. 32 903 Occurrence Handle10.1081/SIM-120013146 Occurrence Handle1:CAS:528:DC%2BD38XlsFKktr0%3D
F. Marchetti C. Pettinari R. Pettinari D. Leonesi A. Lorenzotti (1999) Polyhydron 18 3041 Occurrence Handle10.1016/S0277-5387(99)00230-2 Occurrence Handle1:CAS:528:DyaK1MXnsVGnt7k%3D
Z.Y. Yang R.D. Yang F.S. Li K.B. Yu (2000) Polyhydron 19 2599 Occurrence Handle10.1016/S0277-5387(00)00562-3 Occurrence Handle1:CAS:528:DC%2BD3MXitlamtA%3D%3D
Q.X. Zhen B.H. Ye Q.L. Zhang J.G. Liu H. Li L.N. Ji L. Wang (1999) J. Inorg. Biochem. 76 47 Occurrence Handle10.1016/S0162-0134(99)00107-5 Occurrence Handle1:CAS:528:DyaK1MXmsFaisbo%3D
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Wang, HL., Yang, ZY. & Wang, Bd. Synthesis, Characterization and the Antioxidative Activity of Copper(II), Zinc(II) and Nickel(II) Complexes with Naringenin. Transition Met Chem 31, 470–474 (2006). https://doi.org/10.1007/s11243-006-0015-3
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s11243-006-0015-3