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Synthesis, Characterization and Antibacterial Activity of Some Transition Metal cis-3,7-dimethyl-2,6-octadiensemicarbazone Complexes

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Abstract

The synthesis and characterization of some transition metal cis-3,7-dimethyl-2,6-octadiensemicarbazone (CDOSC) complexes are reported. The ligand CDOSC yields: [ML2 Cl2] and [ML2 Cl2] Cl type complexes, where M = CrIII, MnII, FeIII, CoII, NiII, CuII, ZnII, CdII and HgII, L = CDOSC. Structures of the complexes were determined using elemental analysis, molar conductivity, magnetic measurements, i.r. and electronic, as well as n.m.r spectra. CDOSC acts as a bidentate ligand in all the complexes. All the newly synthesized metal complexes, as well as the ligand, were screened for their antibacterial activity. All the complexes exhibit strong inhibitory action against Gram (+) bacteria Staphylococcus aureus and Gram (−) bacteria Escherichia coli. The antibacterial activities of the complexes are stronger than those of the ligand CDOSC itself.

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Authors and Affiliations

  1. Department of Chemistry, University of Rajasthan, Jaipur, 302004, India

    Renu Sharma, Santosh K. Agarwal, Shikha Rawat & Meena Nagar

Authors
  1. Renu Sharma
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  2. Santosh K. Agarwal
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  3. Shikha Rawat
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  4. Meena Nagar
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Correspondence to Meena Nagar.

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Sharma, R., Agarwal, S.K., Rawat, S. et al. Synthesis, Characterization and Antibacterial Activity of Some Transition Metal cis-3,7-dimethyl-2,6-octadiensemicarbazone Complexes. Transition Met Chem 31, 201–206 (2006). https://doi.org/10.1007/s11243-005-6374-3

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