Abstract
Venous Thrombo-Embolism (VTE) is a serious complication in hospitalized patients but can be preventable. This prospective study addresses risk factors assessment and the use of heparin in this population. About 2,496 non pediatric patients were admitted to Jordan University Hospital between June 12, 2007 and July 19, 2007. A random sample of 624 patients consisting of every fourth admission was chosen. The stratification of risk factors was assessed using Caprini model and the ACCP score. The mean age of the patients (229 males and 395 females) was 45.34 ± 18.3 years. More than 80% of the admitted patients were considered at high risk for VTE but heparin was used in only 26% of the patients. The majority of our patients constitute a high-risk population. Implementation of strategies including educational sessions and risk stratification guidelines can reduce the incidence, morbidity, and mortality of VTE especially in developing countries.
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References
Anderson FA, Spencer FA (2003) Risk factors for venous thromboembolism. Circulation 107:9–16. doi:10.1161/01.CIR.0000078469.07362.E6
Anderson FA, Wheeler HB (1992) Physicians practices in the management of venous thromboembolism: a communitywide survey. J Vasc Surg 16:707–714. doi:10.1067/mva.1992.41080
Rosendaal FR (1999) Risk factors for venous thrombotic disease. Thromb Haemost 82:610–619
Rosendaal FR (1999) Venous thrombosis: a multicausal disease. Lancet 353:1167–1173. doi:10.1016/S0140-6736(98)10266-0
Prandoni P (2005) Acquired risk factors for venous thromboembolism in medical patients. ASH Educ Book 2005:458–461
Caprini JA, Arcelus JI, Reyna JJ (2001) Effective risk stratification of surgical and non-surgical patients for venous thromboembolic disease. Semin Hematol 38:12–19. doi:10.1016/S0037-1963(01)90094-0
Geerts WH, Pineo GF, Heit JA et al (2004) Prevention of venous thromboembolism. Chest 126:338S–400S. doi:10.1378/chest.126.3_suppl.338S
Cohen AT, Agnelli G, Anderson FA et al (2007) Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality. Thromb Haemost 98(4):756–764
Heit JA (2005) Venous thromboembolism: disease burden, outcomes and risk factors. J Thromb Haemost 3(8):1611–1617. doi:10.1111/j.1538-7836.2005.01415.x
Irani-Hakime N, Tamim H, Elias G et al (2001) Factor V R506Q mutation-Leiden: an independent risk factor for venous thrombosis but not coronary artery disease. J Thromb Thrombolysis 11(2):111–116. doi:10.1023/A:1011268531377
Awidi A, Shannak M, Bseiso A et al (1999) High prevalence of factor V Leiden in healthy Jordanian Arabs. Thromb Haemost 81(4):582–584
McLafferty RB, Lohr JM, Caprini JA et al (2007) Results of the National Pilot Screening Program for venous disease by the American venous forum. J Vasc Surg 45:142–148. doi:10.1016/j.jvs.2006.08.079
Kearon C, Kahn SR, Agnelli G, Goldhaber S, Raskob GE, Comerota AJ, American College of Chest Physicians (2008) Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians evidence-based clinical practice guidelines (8th Edition). Chest 133(6, Suppl):454S–545S. doi:10.1378/chest.08–0658
Masroujeh R, Shamseddeen W, Isma’eel H et al (2007) Underutilization of venous thromboemoblism prophylaxis in medical patients in a tertiary care center. J Thromb Thrombolysis 15. [Epub ahead of print]
Dh te R, Pellicer-Coeuret M, Belouet-Moreau C et al (2001) Venous thromboembolism in medical inpatients: prophylaxis with low-weight heparin in a university hospital and prevalence of thromboembolic events. Clin Appl Thromb Hemost 7(1):16–20. doi:10.1177/107602960100700104
South A, Iveson E, Allgar V, Harbison J (2007) The under use of thromboprophylaxis in older medical in-patients: a regional audit. QJM 100(11):685–689. doi:10.1093/qjmed/hcm085
Kakkar AK, Levine M, Pinedo HM et al (2003) Venous thrombosis in cancer patients: insights from the FRONTLINE survey. Oncologist 8(4):381–388. doi:10.1634/theoncologist.8-4-381
Deheinzelin D, Braga AL, Martins LC et al (2006) Incorrect use of thromboprophylaxis for venous thromboembolism in medical and surgical patients: results of a multicentric, observational and cross-sectional study in Brazil. J Thromb Haemost 4:1266–1270. doi:10.1111/j.1538-7836.2006.01981.x
Jaffer AK, Amin AN, Brotman DJ, Deitelzweig SB, McKean SC, Spyropoulos AC (2008) Prevention of venous thromboembolism in the hospitalized medical patient. Cleve Clin J Med 75(Suppl 3):S7–S16
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The authors wish to thank the staff of the quality improvement office in JUH for their tremendous help in this project.
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All the authors have no conflict of interest to declare. Authors have full control of all primary data and that they agree to allow the journal to review the data if requested.
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Awidi, A., Obeidat, N., Magablah, A. et al. Risk stratification for venous thromboembolism in hospitalized patients in a developing country: a prospective study. J Thromb Thrombolysis 28, 309–313 (2009). https://doi.org/10.1007/s11239-008-0291-1
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DOI: https://doi.org/10.1007/s11239-008-0291-1