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Synthesis of Heterocycles from Arylation Products of Unsaturated Compounds: XIII. 5-R1-Benzyl-2-(R2-2-pyridylimino)thiazolidin-4-ones

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Abstract

Meerwein reactions of arenediazonium bromides with methyl and ethyl acrylates gave 3-aryl-2-bromopropionic acid esters which were subjected to cyclocondensation with N-(2-pyridyl)- and N-(6-methyl-2-pyridyl) thioureas to obtain 5-R1-benzyl-2-(R2-2-pyridylimino)thiazolidin-4-ones. The latter were shown to exist in solution as E isomers of the imino form.

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Authors and Affiliations

  1. Ivan Franko L’viv National University, ul. Kirilla i Mefodiya 6, L’viv, 79005, Ukraine

    V. S. Matiichuk, N. D. Obushak & V. M. Tsyalkovskii

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  1. V. S. Matiichuk
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  2. N. D. Obushak
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  3. V. M. Tsyalkovskii
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__________

Translated from Zhurnal Organicheskoi Khimii, Vol. 41, No. 7, 2005, pp. 1071–1075.

Original Russian Text Copyright © 2005 by Matiichuk, Obushak, Tsyalkovskii.

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Matiichuk, V.S., Obushak, N.D. & Tsyalkovskii, V.M. Synthesis of Heterocycles from Arylation Products of Unsaturated Compounds: XIII. 5-R1-Benzyl-2-(R2-2-pyridylimino)thiazolidin-4-ones. Russ J Org Chem 41, 1050–1054 (2005). https://doi.org/10.1007/s11178-005-0292-x

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  • DOI: https://doi.org/10.1007/s11178-005-0292-x

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