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Lactamomethyl derivatives of diphenols: synthesis, structure, and potential biological activity

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Russian Chemical Bulletin Aims and scope

Abstract

A series of mono-, bis-, and tris-substituted lactamomethyl derivatives of diphenols were synthesized. The solution and solid-state structures of these compounds were confirmed by IR and NMR spectroscopy and X-ray diffraction. The in silico evaluation indicated a high probability that these compounds have various biological activities.

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Authors and Affiliations

  1. N. I. Pirogov Russian National Research Medical University, 1 ul. Ostrovityanova, 117997, Moscow, Russian Federation

    Vad. V. Negrebetsky, S. V. Vorobyev, E. P. Kramarova, A. G. Shipov, T. A. Shmigol, Yu. I. Baukov & A. A. Lagunin

  2. Department of Medical Chemistry and Toxicology, 117997, Moscow, Russian Federation

    Vad. V. Negrebetsky, S. V. Vorobyev, E. P. Kramarova, A. G. Shipov, T. A. Shmigol & Yu. I. Baukov

  3. Department of Bioinformatics, 117997, Moscow, Russian Federation

    A. A. Lagunin

  4. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation

    A. A. Korlyukov & D. E. Arkhipov

Authors
  1. Vad. V. Negrebetsky
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  2. S. V. Vorobyev
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  3. E. P. Kramarova
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  4. A. G. Shipov
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  5. T. A. Shmigol
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  6. Yu. I. Baukov
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  7. A. A. Lagunin
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  8. A. A. Korlyukov
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  9. D. E. Arkhipov
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1518–1529, August, 2018.

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Negrebetsky, V.V., Vorobyev, S.V., Kramarova, E.P. et al. Lactamomethyl derivatives of diphenols: synthesis, structure, and potential biological activity. Russ Chem Bull 67, 1518–1529 (2018). https://doi.org/10.1007/s11172-018-2250-0

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  • DOI: https://doi.org/10.1007/s11172-018-2250-0

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