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Synthesis of 1, 8-dioxodecahydroacridines using core–shell structured Fe3O4@MgO MNP's: a solvent-free protocol

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Abstract

This study presented a solvent-free synthesis of 1,8-dioxodecahydroacridine derivatives by a one-pot condensation reaction between cyclic 1,3-diketone, aldehydes using Fe3O4@MgO core–shell structured nanocatalyst up to 89–98% yield. The study was conducted using both the substrate—ammonium acetate and aniline. The nanocatalyst was synthesized by a simple co-precipitation method and found to be both facile and efficient in facilitating the synthesis of the desired derivatives in a short reaction time (5–18 min). The present methodology offers several advantages, such as low cost, magnetically recoverable and reusable catalyst, solvent-free strategy, easy setup, high yield, and short reaction time, clearly portraying the present reaction's green approach.

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Acknowledgements

The authors acknowledge SAIF, IIT, Mumbai, SAIF, IIT, Madras, CSMCRI, Bhavnagar, DST-STIC, Cochin for extending instrumental support.

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Authors and Affiliations

  1. Smt. Chandibai Himathmal Mansukhani College of Arts, Science, Commerce and Management, Ulhasnagar, 421003, India

    Gayatree Shinde

  2. Changu Kana Thakur Arts, Commerce and Science College, New Panvel (W), Navi Mumbai, 410206, India

    Gayatree Shinde & Jyotsna Thakur

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  1. Gayatree Shinde
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Correspondence to Jyotsna Thakur.

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Shinde, G., Thakur, J. Synthesis of 1, 8-dioxodecahydroacridines using core–shell structured Fe3O4@MgO MNP's: a solvent-free protocol. Res Chem Intermed 50, 817–838 (2024). https://doi.org/10.1007/s11164-023-05173-6

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