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Synthesis of pyrazolopyridines catalyzed by nano-CdZr4(PO4)6 as a reusable catalyst

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Abstract

A simple and efficient method for the preparation of pyrazolopyridines by a multicomponent reaction of ethyl acetoacetate, an aldehyde, hydrazine and ammonium acetate using nano-CdZr4(PO4)6 as an efficient catalyst is presented. The main advantages of this protocol include short reaction times, practical simplicity, high yields, recyclable catalysts and applicability to wide range of substrates.

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Acknowledgments

The authors acknowledge a reviewer who provided helpful insights. Meanwhile, the authors are grateful to university of Kashan for supporting this work by Grant No. 159196/XXII.

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Authors and Affiliations

  1. Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, 51167, Iran

    Javad Safaei-Ghomi, Hossein Shahbazi-Alavi & Reyhaneh Sadeghzadeh

  2. School of Chemistry, College of Science, University of Tehran, Tehran, 14155-6455, Iran

    Abolfazl Ziarati

Authors
  1. Javad Safaei-Ghomi
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  2. Hossein Shahbazi-Alavi
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  3. Reyhaneh Sadeghzadeh
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  4. Abolfazl Ziarati
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Correspondence to Javad Safaei-Ghomi.

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Safaei-Ghomi, J., Shahbazi-Alavi, H., Sadeghzadeh, R. et al. Synthesis of pyrazolopyridines catalyzed by nano-CdZr4(PO4)6 as a reusable catalyst. Res Chem Intermed 42, 8143–8156 (2016). https://doi.org/10.1007/s11164-016-2585-9

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  • DOI: https://doi.org/10.1007/s11164-016-2585-9

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