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Racemization of chiral amino alcohols III: Effect of Mg or Ca addition on the activity and stability of the Co/γ-Al2O3 catalyst

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Abstract

The racemization of R-(-)-2-amino-1-butanol in a reaction using Co/γ-Al2O3 catalysts and catalysts modified by Mg or Ca was investigated in this paper. Complete racemization was achieved with a yield of over 83% at using the Mg modified Co/γ-Al2O3 catalyst under optimized reaction conditions of 170°C and 2.5 MPa of H2. The catalysts were thoroughly characterized by XRD, XPS, TPR, SEM and TEM. The addition of Mg and Ca may be advantageous for dispersing and stabilizing the active species of the Co/γ-Al2O3 catalyst, protecting from sintering, significantly improving its catalytic activity and stability.

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Authors and Affiliations

  1. College of Chemistry and Environmental Science, Hebei University, Baoding, Hebei, 071002, P.R.China

    Guoyi Bai, Chenfang Zhang & Huisen Ning

  2. School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, P.R.China

    Yuecheng Zhang, Haijun Yu, Fei He & Ligong Chen

Authors
  1. Guoyi Bai
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  2. Chenfang Zhang
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  3. Yuecheng Zhang
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  4. Haijun Yu
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  5. Fei He
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  6. Huisen Ning
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  7. Ligong Chen
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Correspondence to Guoyi Bai.

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Bai, G., Zhang, C., Zhang, Y. et al. Racemization of chiral amino alcohols III: Effect of Mg or Ca addition on the activity and stability of the Co/γ-Al2O3 catalyst. React Kinet Catal Lett 90, 373–380 (2007). https://doi.org/10.1007/s11144-007-5037-0

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  • DOI: https://doi.org/10.1007/s11144-007-5037-0

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