Abstract
Purpose
Longitudinal studies addressing change in health-related quality of life (HRQoL) following a diagnosis of cancer have mainly focused on a single cancer type, and little is known about the differences in HRQoL over time according to the type of tumor. The current study aims to compare the change in HRQoL over 2 years following breast cancer or melanoma diagnosis and socio-demographic variables associated with HRQoL over time.
Methods
Patients recently diagnosed with breast cancer (n = 215) or melanoma (n = 78) completed surveys within 1 month of diagnosis and 6, 12, and 24 months later. Multilevel modeling analyses were used to compare the evolution over time of HRQoL dimensions, as measured by the EORTC QLQ-C30, in both cancers. Longitudinal effect of socio-demographic variables on HRQoL was also assessed.
Results
Consistent with the literature, both cancer patients experienced decreased HRQoL scores following the diagnosis before improving over time. However, our analyses revealed that this rebound effect may occur at diverse times over the course of the illness according to the type of cancer. In addition, HRQoL over time was positively associated with age and negatively related to living with a partner regardless of the type of cancer.
Conclusions
The results of the present study suggest that support in hospital units should be specific and depend on the cancer type.
Similar content being viewed by others
References
Härtl, K., Schennach, R., Müller, M., Engel, J., Reinecker, H., Sommer, H., et al. (2010). Quality of life, anxiety, and oncological factors: A follow-up study of breast cancer patients. Psychosomatics, 51(2), 112–123.
Høyer, M., Johansson, B., Nordin, K., Bergkvist, L., Ahlgren, J., Lidin-Lindqvist, A., et al. (2011). Health-related quality of life among women with breast cancer: A population-based study. Acta Oncologica, 50(7), 1015–1026.
Lee, E. S., Lee, M. K., Kim, S. H., Ro, J. S., Kang, H. S., Kim, S. W., et al. (2011). Health-related quality of life in survivors with breast cancer 1 year after diagnosis compared with the general population: A prospective cohort study. Annals of Surgery, 253(1), 101–108.
Jansen, L., Koch, L., Brenner, H., & Arndt, V. (2010). Quality of life among long-term (≥5 years) colorectal cancer survivors—Systematic review. European Journal of Cancer, 46(16), 2879–2888.
Klein, D., Mercier, M., Abeilard, E., Puyraveau, M., Danzon, A., Dalstein, V., et al. (2011). Long-term quality of life after breast cancer: A French registry-based controlled study. Breast Cancer Research and Treatment, 129(1), 125–1234.
Schmidt, M. E., Chang-Claude, J., Vrieling, A., Heinz, J., Flesch-Janys, D., & Steindorf, K. (2012). Journal of Cancer Survivorship, 6(1), 11–19.
Lehto, U. S., Ojanen, M., & Kellokumpu-Lehtinen, P. (2005). Predictors of quality of life in newly diagnosed melanoma and breast cancer patients. Annals of Oncology, 16(5), 805–816.
Engel, J., Schlesinger-Raab, A., Emeny, R., Hölzel, D., & Schubert-Fritschle, G. (2014). Quality of life in women with localised breast cancer or malignant melanoma two years after initial treatment: A comparison. International Journal of Behavioral Medicine, 21(3), 478–486.
Kasparian, N. A., McLoone, J. K., & Butow, P. N. (2009). Psychological responses and coping strategies among patients with malignant melanoma: A systematic review of the literature. Archives of Dermatology, 145(12), 1415–1427.
Vurnek, Z. M., Buljan, M., Blajić, I., & Situm, M. (2008). Psychological status and illness perceptions in patients with melanoma. Collegium Antropologicum, 32(2), 75–78.
Schou, I., Ekeberg, O., Sandvik, L., Hjermstad, M. J., & Ruland, C. M. (2005). Multiple predictors of health-related quality of life in early stage breast cancer. Data from a year follow-up study compared with the general population. Quality of Life Research, 14(8), 1813–1823.
Härtl, K., Engel, J., Herschbach, P., Reinecker, H., Sommer, H., & Friese, K. (2010). Personality traits and psychosocial stress: Quality of life over 2 years following breast cancer diagnosis and psychological impact factors. Psycho-Oncology, 19(2), 160–169.
King, M. T., Kenny, P., Shiell, A., Hall, J., & Boyages, J. (2000). Quality of life three months and one year after first treatment for early stage breast cancer: Influence of treatment and patient characteristics. Quality of Life Research, 9(7), 789–800.
Cormier, J. N., Cromwell, K. D., & Ross, M. I. (2012). Health-related quality of life in patients with melanoma: Overview of instruments and outcomes. Dermatologic Clinics, 30(2), 245–254.
Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., et al. (1993). The European Organisation for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85(5), 365–376.
Fayers, P. M., Aaronson, N. K., Bjordal, K., Groenvold, M., Curran, D., Bottomley, A., et al. (2001). The EORTC QLQ-C30 Scoring Manual (3rd ed.). Brussels: European Organisation for Research and Treatment of Cancer.
Akaike, H. (1974). A new look at the statistical model identification. System identification and time-series analysis. IEEE Transactions on Automatic Control, 19(6), 716–723.
INCa. (2014). La vie deux ans après un diagnostic de cancer: De l’annonce à l’après cancer [Life two years after a diagnosis of cancer: From the diagnosis to the post-cancer times]. http://www.inserm.fr/…/rapport_complet_la-vie-2-ans-apres-un-diagnostic-de-cancer-2014-2.pdf. Accessed 03 June 2015.
Le Coroller-Soriano, A. G., Bouhnik, A. D., Préau, M., Malavolti, L., Julian-Reynier, C., Auquier, P., et al. (2010). Does cancer survivors’ health-related quality of life depend on cancer type? Findings from a large French national sample 2 years after cancer diagnosis. European Journal of Cancer Care, 20(1), 132–140.
Al-Shakhli, H., Harcourt, D., & Kenealy, J. (2006). Psychological distress surrounding diagnosis of malignant and nonmalignant skin lesions at a pigmented lesion clinic. Journal of Plastic, Reconstructive and Aesthetic Surgery, 59(5), 479–486.
Montazeri, A., Vahdaninia, M., Harirchi, I., Ebrahimi, M., Khaleghi, F., & Jarvandi, S. (2008). Quality of life in patients with breast cancer before and after diagnosis: An eighteen months follow-up study. BMC Cancer. doi:10.1186/1471-2407-8-330.
Rottmann, N., Dalton, S. O., Christensen, J., Frederiksen, K., & Johansen, C. (2010). Self-efficacy, adjustment style and well-being in breast cancer patients: A longitudinal study. Quality of Life Research, 19(6), 827–836.
Ashing-Giwa, K. T., & Lim, J. W. (2009). Examining the impact of socioeconomic status and socioecologic stress on physical and mental health quality of life among breast cancer survivors. Oncology Nursing Forum, 36(1), 79–88.
Short, P. F., & Mallonee, E. L. (2006). Income disparities in the quality of life of cancer survivors. Medical Care, 44(1), 16–23.
Tessier, P., Lelorain, S., & Bonnaud-Antignac, A. (2012). A comparison of the clinical determinants of health-related quality of life and subjective well-being in long-term breast cancer survivors. European Journal of Cancer Care, 21(5), 692–700.
Kornblith, A. B., Powell, M., Regan, M. M., Bennett, S., Krasner, C., & Moy, B. (2007). Long-term psychosocial adjustment of older vs. younger survivors of breast and endometrial cancer. Psycho-Oncology, 16(10), 895–903.
Kroenke, C. H., Rosner, B., Chen, W. Y., Kawachi, I., Colditz, G. A., & Holmes, M. D. (2004). Functional impact of breast cancer by age at diagnosis. Journal of Clinical Oncology, 22(10), 1849–1856.
Lam, W. W., Li, W. W., Bonanno, G. A., Mancini, A. D., Chan, M., Or, A., et al. (2012). Trajectories of body image and sexuality during the first year following diagnosis of breast cancer and their relationship to 6 years psychosocial outcomes. Breast Cancer Research and Treatment, 131(3), 957–967.
Rosenberg, S. M., Tamimi, R. M., Gelber, S., Ruddy, K. J., Kereakoglow, S., Borges, V. F., et al. (2013). Body image in recently diagnosed young women with early breast cancer. Psycho-Oncology, 22(8), 1849–1855.
Acknowledgments
The authors would like to extend their sincere thanks to the patients who agreed to take part in the study. They would also like to thank the Ligue Nationale contre le Cancer for its financial support and the Plateforme nationale «Qualité de vie et cancer».
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Rights and permissions
About this article
Cite this article
Bourdon, M., Blanchin, M., Tessier, P. et al. Changes in quality of life after a diagnosis of cancer: a 2-year study comparing breast cancer and melanoma patients. Qual Life Res 25, 1969–1979 (2016). https://doi.org/10.1007/s11136-016-1244-3
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11136-016-1244-3