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Longitudinal associations between asthma control, medication adherence, and quality of life among adolescents: results from a cross-lagged analysis

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Abstract

Purpose

It is not completely clear whether and how medication adherence, asthma control, and quality of life (QOL) predict each other over time. Therefore, the aim of the present study was to examine the longitudinal associations between asthma control, medication adherence, and quality of life among adolescents.

Methods

In this 3-wave longitudinal study, adolescents (N = 139, Mean age = 11.8) completed questionnaires about their medication adherence (Medication Adherence Report Scale for Asthma), asthma control (Asthma Control Questionnaire), and QOL (Adolescent Asthma Quality of Life Questionnaire) during home visits in the spring/summer of 2011, 2012, and 2013. Cross-lagged analyses examined temporal interrelations between the three variables over the course of 3 years.

Results

Higher QOL at baseline predicted increased medication adherence at follow-up (T2), but did not predict changes in asthma control over time. Medication adherence and asthma control did not predict changes in QOL over time. There were no associations between asthma control and medication adherence over time.

Conclusions

Interventions could focus on increasing QOL to increase medication adherence in adolescents with asthma.

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Acknowledgments

We would like to thank all of the families who were willing to participate in this study and the Lung Foundation Netherlands who supported this study (Grant Number 3.4.09.012).

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Authors and Affiliations

  1. Behavioural Science Institute (BSI), Faculty of Social Sciences, Radboud University Nijmegen, Montessorilaan 3, 6525 HR, Nijmegen, The Netherlands

    Dana Tiggelman, Monique O. M. van de Ven & Rutger C. M. E. Engels

  2. Care and Public Health Research (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands

    Onno C. P. van Schayck

Authors
  1. Dana Tiggelman
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  2. Monique O. M. van de Ven
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  3. Onno C. P. van Schayck
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  4. Rutger C. M. E. Engels
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Correspondence to Dana Tiggelman.

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Tiggelman, D., van de Ven, M.O.M., van Schayck, O.C.P. et al. Longitudinal associations between asthma control, medication adherence, and quality of life among adolescents: results from a cross-lagged analysis. Qual Life Res 24, 2067–2074 (2015). https://doi.org/10.1007/s11136-015-0945-3

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