Abstract
Objective
To evaluate whether an interdisciplinary intervention program on lifestyle results in better quality of life (QoL) and lower frequencies of depression and binge eating disorder (BED) in individuals at risk for type 2 diabetes mellitus.
Methods
A total of 177 individuals (32.2% men, age 55.4 ± 12.5 years) at risk for diabetes were allocated to a 9-month traditional (TI) or intensive interdisciplinary intervention (II) on dietary habits and physical activity including psychoeducative groups. They were submitted to questionnaires and clinical and laboratory examinations. Predictors of non-adherence were analyzed by logistic regression.
Results
Only individuals submitted to II had blood pressure and plasma glucose levels reduced. Frequencies of depression reduced in both interventions but of BED only in II (28.0–4.0%, P < 0.001). Increments in the scores of SF-36 domains (physical functioning: 11.1 ± 14.0 vs. 5.3 ± 13.0, role-emotional: 20.4 ± 40.2 vs. 6.2 ± 43.8, P = 0.05) were greater in the II than in TI, respectively. Changes in SF-36 correlated with decreases in anthropometry, blood pressure and glucose levels, depression and BED scores. Male gender was independently associated with non-adherence to the II.
Conclusions
In addition to metabolic benefits, an interdisciplinary approach may induce desirable extrametabolic effects, favoring the control of psychiatric disorders and improving the QoL of individuals at risk for diabetes.
Similar content being viewed by others
References
King, H., Aubert, R. E., & Herman, W. H. (1998). Global burden of diabetes, 1995–2025. Prevalence, numerical estimates and projections. Diabetes Care, 21, 1414–1431.
Tuomilehto, J., Lindstrom, J., Eriksson, J. G., Valle, T. T., Hamalainen, H., Ilanne-Parikka, P., et al. (2001). Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. New England Journal of Medicine, 344, 1343–1350.
Knowler, W. C., Barrett-Conner, E., Fowler, S. E., Hamman, R. F., Lachin, J. M., Walker, E. A., et al. (2002). Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. New England Journal of Medicine, 346, 393–403.
WHO–World Health Organization. (1946). Constitution of the World Health Organization. Genebra: World Health Organization.
Lustman, P. J., Anderson, R. J., Freedland, K. E., de Groot, M., Carney, R. M., & Clouse, R. E. (2000). Depression and poor glycemic control. Diabetes Care, 23(7), 934–942.
Katon, W. J., Rutter, C., Simon, G., Lin, W. H. B., Ludman, E., Ciechanowski, P., et al. (2003). The association of comorbid depression with mortality in patients with type 2 diabetes. Diabetes Care, 28, 2668–2672.
Campayo, A., de Jonge, P., Roy, J. F., Saz, P., Camara, C., Quintanilla, M. A., Marcos, G., et al. (2010). Depressive disorder and incident diabetes mellitus: The effect of characteristics of depression. American Journal of Psychiatry, 167(5):496–497.
Bogner, H. R., Post, E. P., Morales, K. H., & Bruce, M. L. (2007). Diabetes, depression, and death: a randomized controlled trial of a depression treatment program for older adults based in primary care (PROSPECT). Diabetes Care, 30, 3005–3010.
Young-Hyman, D., & Davis, C. L. (2010). Disordered eating behavior in individuals with diabetes: Importance of context, evaluation, and classification. Diabetes Care, 33(3), 683–689.
Cerrelli, F., Manini, R., Forlani, G., Baraldi, L., Melchionda, N., & Marchesini, G. (2005). Eating behavior affects quality of life in type 2 diabetes mellitus. Eating and Weight Disorders, 10(4), 251–257.
Meneghini, L. F., Spadola, J., & Florez, H. (2006). Prevalence and associations of binge eating disorder in a multiethnic population with type 2 diabetes. Diabetes Care, 29(12), 2760.
Williamson, D. A., Rejeski, J., Lang, W., Van Dorsten, B., Fabricatore, A. N., & Toledo, K. (2009). Impact of a weight management program on health-related quality of life in overweight adults with type 2 diabetes. Archives of Internal Medicine, 169, 163–171.
Gensichen, J., Torge, M., Peitz, M, Wendt-Hermainski, H., Beyer, M., Rosemann, T., et al. (2005). Case management for the treatment of patients with major depression in general practices—rationale, design and conduct of a cluster randomized controlled trial—PRoMPT (Primary care monitoring for depressive patient’s trial) [ISRCTN66386086]—Study protocol public health. 5:101. In: http://www.biomedcentral.com/1471-2458/5/101.
Ware, J. E., Jr., Gandek, B., Kosinski, M., Aaronson, N. K., Apolone, G., Brazier, J., et al. (1998). The equivalence of SF-36 summary health scores estimated using standard and country-specific algorithms in 10 countries: results from the IQOLA project. International Quality of Life Assessment. Journal of Clinical Epidemiology, 51, 1167–1170.
Campolina, A. G., & Ciconelli, R. M. (2006). Qualidade de vida e medidas de utilidade: parâmetros clínicos para as tomadas de decisão em saúde. Pan American Journal of Public Health, 19(2), 128–136.
Spitzer, R. L., Kroenke, K., Williams, J. B., Linzer, M., deGruy, F. V., Hahn, S. R., et al. (1994). Utility of a new procedure for diagnosing mental disorders in primary care. The PRIME MD 1000 study. JAMA., 272(22), 1749–1756.
APA—American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). DC: Washington.
Lasa, L., Ayuso-Mateos, J. L., Vázquez-Barquero, J. L., Díez-Manrique, F. J., & Dowrick, C. F. (2000). The use of the Beck depression inventory to screen for depression in the general population: a preliminary analysis. Journal of Affective Disorders, 57, 261–265.
Gormally, J., Black, S., Daston, S., & Rardin, D. (1982). The assessment of binge eating severity among obese persons. Addictive Behaviors, 7, 47–55.
Gami, A. S., Witt, B. J., Howard, D. E., Erwin, P. J., Gami, L. A., Somers, V. K., et al. (2007). Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. Journal of the American College of Cardiology, 49, 403–414.
Ford, E. S., Schulze, M. B., Pischon, T., Bergmann, M. M., & Boeing, H. (2008). Metabolic syndrome and risk of incident diabetes: findings from the European prospective investigation into cancer and nutrition-postdam study. Cardiovascular Diabetology, 12, 7–35.
ADA—American Diabetes Association (1997). Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care, 20, 1183–1197.
IDF—International Diabetes Federation (2006). Diabetes Atlas, (3ªrd ed.,). Brussels: International Diabetes Federation.
Craig, C. L., Marshall, A. L., Sjostrom, M., Bauman, A. E., Booth, M. L., Ainsworth, B. E., et al. (2003). International physical activity questionnaire: 12-country reliability and validity. Medicine and Science Sports and Exercise., 35(8), 1381–1395.
Florindo, A. A., Guimarães, V. V., Cezar, C. L., Barros, M. B., Alves, M. C., & Goldbaum, M. (2009). Epidemiology of leisure, transportation, occupational and household physical activity: prevalence and associated factors. Journal of Physical Activity Health, 6(5), 625–632.
Nutrition Coordinating Center (NCC) (2005). Nutrition data system for research-NDS-R (computer program), University of Minnesota, Minneapolis.
Beck, A. T., Steer, R. A., & Garbin, M. G. (1988). Psychometric properties of the Beck depression inventory: twenty-five years of evaluation. Clinical Psychology Review, 8, 77–100.
Cunha, J. A. (2001). Manual da versão em português das escalas Beck. São Paulo: Casa do Psicólogo.
Freitas, S., Lopes, C. S., Coutinho, W., & Appolinario, J. C. (2001). Tradução e adaptação para o português da Escala de Compulsão Alimentar Periódica. Revista Brasileira de Psiquiatria, 23(4), 215–220.
SPSS Incorporation (2009). Statistical package for the social science for windows student version/SPSS (computer program) release 17.0. Chicago: Marketing department.
Heymsfield, S. B., Segal, K. R., Hauptman, J., Lucas, C. P., Boldrin, M. N., Rissanen, A., et al. (2000). Effects of weight loss with orlistat on glucose tolerance and progression to type 2 diabetes in obese adults. Archives of Internal Medicine, 160(9), 1321–1326.
Chiasson, J. L., Josse, R. G., Gomis, R., Hanefeld, M., Karasik, A., & Laakso, M. (2002). Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet, 359(9323), 2072–2077.
Papelbaum, M., Moreira, R. O., Ellinger, V. C. M., Zagury, L., & Appolinário, J. C. (2001). Comorbidade psiquiátrica no paciente diabético. Psiquiatria na Prática Médica, 34(3), 82–85.
Ackermann, R. T., Edelstein, S. L., Venkat, N. K. M., Zhang, P., Engelgau, M. M., Herman, W.H., et al. (2009). Changes in health state utilities with changes in body mass in the diabetes prevention program. Obesity, 17(12):2176–2181.
Trento, M., Gamba, S., Gentile, L., Grassi, G., Miselli, V., Morone, G., et al. (2010). Rethink organization to improve education and outcomes (ROMEO): A multicenter randomized trial of lifestyle intervention by group care to manage type 2 diabetes. Diabetes Care, 33(4), 745–747.
Spitzer, R. L., Yanovski, S., Waden, T., Wing, R., Marcus, M. D., & Stunkard, A. (1993). Binge eating disorder: Its further validation in multisite study. International Journal Eating Disorder, 13, 137–153.
Schelling, S., Munsch, S., Meyer, A. H., & Margraf, J. (2011). Relationship between motivation for weight loss and dieting and binge eating in a representative population survey. International Journal of Eating Disorders, 44(1), 39–43.
Kenardy, J., Mensch, M., Bowen, K., Green, B., & Walton, J. (2002). Group therapy for binge eating in type 2 diabetes: a randomized trial. Diabetic Medicine, 19(3), 234–239.
Bulik, C., Brownley, K. A., & Shapiro, J. R. (2007). Diagnosis and management of binge eating disorder. World Psychiatry, 6, 142–148.
Grucza, R. A., Przybeck, T. R., & Cloninger, C. R. (2007). Prevalence and correlates of binge eating disorder in a community sample. Comprehensive Psychiatry, 48, 124–131.
Mather, A. A., Cox, B. J., Enns, M. W., & Sareen, J. (2009). Associations of obesity with psychiatri disorders and suicidal behaviors in a nationally representative sample. Journal of Psychosomatic Research, 66, 277–285.
Capuron, L., Poitou, C., & Machaux-Tholliez, D. (2010) Relationship between adiposity, emotional status and eating behaviour in obese women: role of inflammation. doi:10.1017/S0033291710001984.
Rubin, R. R., Ma, Y., Marrero, D. G., Peyrot, M., Barrett-Connor, E. L., Kahn, S. E., et al. (2008). Diabetes prevention program research group. Elevated depression symptoms, antidepressant medicine use, and risk of developing diabetes during the diabetes prevention program. Diabetes Care, 31(3):420–426.
Lustman, P. J., Griffith, L. S., Freedland, K. E., Kisse, S. S., & Clouse, R. E. (1998). Cognitive behavior therapy for depression in type 2 diabetes mellitus. A randomized, controlled trial. Annals of Internal Medicine, 129(8), 613–621.
Demakakos, P., Pierce, M. B., & Hardy, R. (2010). Depressive symptoms and risk of type 2 diabetes in a national sample of middle-aged and older adults: The English longitudinal study of aging. Diabetes Care, 33(4), 792–797.
Raison, C. L., Capuron, L., & Miller, A. H. (2006). Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunology, 27(1), 24–31.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Cezaretto, A., Siqueira-Catania, A., de Barros, C.R. et al. Benefits on quality of life concomitant to metabolic improvement in intervention program for prevention of diabetes mellitus. Qual Life Res 21, 105–113 (2012). https://doi.org/10.1007/s11136-011-9919-2
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11136-011-9919-2