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Validity and reliability of Persian version of chronic liver disease questionnaire (CLDQ)

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Abstract

Purpose

The aim of this study is to test the psychometric properties of the Persian version of the Chronic Liver Disease Questionnaire (CLDQ) in Iranian candidates for liver transplantation.

Method

One hundred and fifty-five consecutive adult patients awaiting liver transplantation completed the Persian version of CLDQ and the short-form health survey (SF-36). The etiology of cirrhosis, Child Pugh classification and Model for End stage Liver Disease (MELD) scores were taken from medical records.

Results

The scaling success rate for convergent validity was 100% for all domains, and the success rate for item discriminant validity was 95.8% (139/145). The internal consistency (Cronbach α) for the domains ranged from 0.65 to 0.89. Multitrait–multimethod correlation matrix and factor analysis revealed that the CLDQ and SF-36 measure different constructs of quality of life.

Conclusion

The Persian version of the CLDQ, a disease-specific questionnaire for measuring health-related quality of life, is accepted by liver transplantation candidates with adequate reliability and validity. There is no significant correlation of Child Pugh classification and MELD score with quality of life.

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Acknowledgments

We would like to express our appreciation to all patients for consenting to participate in this study. We also thank Dr Zobair M. Younossi for permission to use and translate the CLDQ English version into Persian. In addition, we thank Raymond McCarthy Bergeron and Meghdad Asadi for English editing.

Author information

Authors and Affiliations

  1. Anesthesiology and Critical Care Research Center, Anesthesia Department, Shiraz University of Medical Sciences, Shiraz, Iran

    Hilda Mahmoudi

  2. Department of Biostatistics, Shiraz University of Medical Sciences, Shiraz, Iran

    Peyman Jafari

  3. Gastroenterohepatology Research Center, Internal Medicine Department, Shiraz University of Medical Sciences, Shiraz, Iran

    Mahvash Alizadeh-Naini

  4. Shiraz Organ Transplant Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Siyavash Gholami

  5. Shiraz Organ Transplant Center, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran

    Seyed Ali Malek-Hosseini

  6. Anesthesiology and Critical Care Research Center, Shiraz Organ Transplant Center, Department of Anesthesiology, Shiraz University of Medical Sciences, Shiraz, Iran

    Sina Ghaffaripour

Authors
  1. Hilda Mahmoudi
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  2. Peyman Jafari
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  3. Mahvash Alizadeh-Naini
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  4. Siyavash Gholami
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  5. Seyed Ali Malek-Hosseini
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  6. Sina Ghaffaripour
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Corresponding author

Correspondence to Sina Ghaffaripour.

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Mahmoudi, H., Jafari, P., Alizadeh-Naini, M. et al. Validity and reliability of Persian version of chronic liver disease questionnaire (CLDQ). Qual Life Res 21, 1479–1485 (2012). https://doi.org/10.1007/s11136-011-0059-5

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  • DOI: https://doi.org/10.1007/s11136-011-0059-5

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