Abstract
The use of preference-based generic instruments to measure the health-related quality of life of a general population or of individuals suffering from a specific disease has been increasing. However, there are several discrepancies between instruments in terms of utility results. This study compares SF-6D and EQ-5D when administered to patients with cataracts and aims at explaining the differences. Agreement between EQ-5D and SF-6D health state classifications was assessed by correlation coefficients. Simple correspondence analysis was used to assess the agreement among the instrument’s descriptive systems and to investigate similarities between dimensions’ levels. Cluster analysis was used to classify SF-6D and EQ-5D levels into homogeneous groups. There was evidence of floor effects in SF-6D and ceiling effects in EQ-5D. Comparisons of means showed that SF-6D values exceeded EQ-5D values. Agreement between both instruments was high, especially between similar dimensions. However, different valuation methods and scoring algorithms contributed to the main differences found. We suggest that one or both instruments should be revised, in terms of their descriptive systems or their scoring algorithms, in order to overcome the weakness found.
Similar content being viewed by others
References
Brooks, R. (1996). EuroQol: The current state of play. Health Policy (Amsterdam), 37, 53–72. doi:10.1016/0168-8510(96)00822-6.
Dolan, P. (1997). Modelling valuations for EuroQol health states. Medical Care, 35, 1095–1108. doi:10.1097/00005650-199711000-00002.
Kind, P., Hardman, G., & Macran, S. (1999). UK Population Norms for EQ-5D. Discussion Paper 172. University of York: Centre for Health Economics.
Torrance, G., Furlong, W., Feeny, D., & Boyle, M. (1995). Multi-attribute preference functions: Health utilities index. PharmacoEconomics, 7, 503–520. doi:10.2165/00019053-199507060-00005.
Torrance, G., Feeny, D., Furlong, W., Barr, R., Zhang, Y., & Wang, Q. (1996). Multi-attribute utility function for a comprehensive health status classification system: Health utilities index mark 2. Medical Care, 34(7), 702–722. doi:10.1097/00005650-199607000-00004.
McCabe, C., Stevens, K., Roberts, J., & Brazier, J. (2005). Health state values for the HUI2 descriptive system: Results from a UK survey. Health Economics, 14, 231–244. doi:10.1002/hec.925.
Brazier, J., Usherwood, T., Harper, R., & Thomas, K. (1998). Deriving a preference-based single index from the UK SF-36 health survey. Journal of Clinical Epidemiology, 51(11), 1115–1128. doi:10.1016/S0895-4356(98)00103-6.
Brazier, J., Roberts, J., & Deverill, M. (2002). The estimation of a preference-based measure of health from the SF-36. Journal of Health Economics, 21, 271–292. doi:10.1016/S0167-6296(01)00130-8.
Kaplan, R. M., Bush, J. W., & Berry, C. C. (1976). Health status: Types of validity and the index of well-being. Health Services Research, 11(4), 478–507.
Kaplan, R. M., Ganiats, T. G., Sieber, W. J., & Anderson, J. P. (1998). The quality of well-being scale: Critical similarities and differences with SF-36. International Journal for Quality in Health Care, 10, 509–520. doi:10.1093/intqhc/10.6.509.
Anderson, J. P., Kaplan, R. M., Berry, C. C., Bush, J. W., & Rumbaut, R. G. (1989). Interday reliability of function assessment for a health status measure: The quality of well-being scale. Medical Care, 27, 1076–1083. doi:10.1097/00005650-198911000-00008.
Osborne, R., Hawthorne, G., Lew, E., & Gray, L. (2003). Quality of life assessment in the community-dwelling elderly: Validation of the assessment of quality of life (AQoL) instrument and comparison with the SF-36. Journal of Clinical Epidemiology, 56(2), 138–147. doi:10.1016/S0895-4356(02)00601-7.
Hawthorne, G., & Osborne, R. (2005). Population norms and meaningful differences for the assessment of quality of life (AQoL) measure. Australian and New Zealand Journal of Public Health, 29(2), 136–142. doi:10.1111/j.1467-842X.2005.tb00063.x.
Brazier, J., Roberts, J., Tsuchiya, A., & Busschbach, J. (2004). A comparison of the EQ-5D and SF-6D across seven patient groups. Health Economics, 13, 873–884. doi:10.1002/hec.866.
Petrou, S., & Hockley, C. (2005). An investigation into the empirical validity of the EQ-5D and SF-6D based on hypothetical preferences in a general population. Health Economics, 14(11), 1169–1189. doi:10.1002/hec.1006.
Stavem, K., Frøland, S. S., & Hellum, K. B. (2005). Comparison of preference-based utilities of the 15D, EQ-5D and SF-6D in patients with HIV/AIDS. Quality of Life Research, 14, 971–980. doi:10.1007/s11136-004-3211-7.
Lamers, L., Bouwmans, C., van Straten, A., Donker, M., & Hakkaart, L. (2006). Comparison of EQ-5D and SF-6D utilities in mental health patients. Health Economics, 15(11), 1229–1236. doi:10.1002/hec.1125.
Marra, C., Woolcott, J., Kopec, J., Shojania, K., Offer, R., Brazier, J., et al. (2005). A comparison of generic, indirect utility measures (the HUI2, HUI3, SF-6D, and the EQ-5D) and disease-specific instruments (the RAQoL and The HAQ) in rheumatoid arthritis. Social Science & Medicine, 60, 1571–1582. doi:10.1016/j.socscimed.2004.08.034.
Feeny, D., Wu, L., & Eng, K. (2004). Comparing short form 6D, standard gamble and health utilities index mark 2 and mark 3 utility scores: Results of total hip arthroplasty patients. Quality of Life Research, 13(10), 1659–1670. doi:10.1007/s11136-004-6189-2.
Tsuchiya, A., Brazier, J., & Roberts, J. (2006). Comparison of valuation methods used to generate the EQ-5D and the SF-6D value sets. Journal of Health Economics, 25(2), 334–346. doi:10.1016/j.jhealeco.2005.09.003.
Marra, C., Esdaile, J., Guh, D., Kopec, J., Brazier, J., & Koehler, B. (2004). Chalmers, A., Anis, A. A comparison of four indirect methods of assessing utility values in rheumatoid arthritis. Medical Care, 42(11), 1125–1131. doi:10.1097/00005650-200411000-00012.
Pickard, A., Simon, J., Jeffrey, A., & Feeny, D. H. (2005). Responsiveness of generic health-related quality of life in stroke. Quality of Life Research, 14, 207–219. doi:10.1007/s11136-004-3928-3.
Longworth, L., & Bryan, S. (2003). An empirical comparison of EQ-5D and SF-6D in liver transplant patients. Health Economics, 12(12), 1061–1067. doi:10.1002/hec.787.
Hawthorne, G., Richardson, J., & Atherton Day, N. (2001). A comparison of the assessment of quality of life (AQoL) with four other generic utility instruments. Annals of Medicine, 33, 358–370. doi:10.3109/07853890109002090.
Kopec, J., & Willison, K. (2003). A comparative review of four preference-weighted measures of health-related quality of life. Journal of Clinical Epidemiology, 56(4), 317–325. doi:10.1016/S0895-4356(02)00609-1.
Everitt, B. S., & Dunn, G. (2001). Applied Multivariate Data Analysis. London: Arnold.
Bryan, S., & Longworth, L. (2005). Measuring health-related utility: Why the disparity between EQ-5D and SF-6D? The European Journal of Health Economics, 50, 253–260. doi:10.1007/s10198-005-0299-9.
Holland, R., Smith, R., Harvey, I., Swift, L., & Lenaghan, E. (2004). Assessing quality of life in the elderly: A direct comparison of the EQ-5D and AQoL. Health Economics, 13(8), 793–805. doi:10.1002/hec.858.
O’Brien, B., Spath, M., Blackhouse, G., Severens, J., Dorian, P., & Brazier, J. (2003). A view from the bridge: Agreement between the SF-6d utility algorithm and the health utilities index. Health Economics, 12(11), 975–981. doi:10.1002/hec.789.
Gerard, K., Nicholson, T., Mulle, M., Mehta, R., & Roderick, P. (2004). EQ-5D versus SF-6D in an older, chronically Ill patient group. Applied Health Economics and Health Policy, 3(2), 91–102. doi:10.2165/00148365-200403020-00005.
Franks, P., Lubetkin, E., Gold, M., Tancredi, D., & Jia, H. (2004). Mapping the SF-12 to the EuroQol EQ-5D index in a national US sample. Medical Decision Making, 24(3), 247–254. doi:10.1177/0272989X04265477.
Gray, A., Rivero-Arias, O., & Clarke, P. (2006). Estimating the association between SF-12 responses and EQ-5D utility values by response mapping. Medical Decision Making, 26(18), 18–29. doi:10.1177/0272989X05284108.
Tsuchiya, A., Brazier, J., McColl, E., & Parkin, D. (2002). Deriving preference-based single indices from non-preference based condition-specific instruments: Converting AQLQ into EQ5D indices. Discussion Paper 02/1. The University of Sheffield: Sheffield Health Economics Group.
Acknowledgements
The authors wish to thank Dr. Jorge Correia and his medical and nursing team, who collected the data. The authors are grateful to Professor John Brazier for providing the SF-6D algorithm. We also thank two anonymous referees for their constructive comments and suggestions, which have considerably improved the paper. Earlier versions of this paper have been presented at the 6th European Conference on Health Economics 2006, Budapest, Hungary and at the 13th Annual Conference of the International Society for Quality of Life Research 2006, Lisbon, Portugal. Lara Ferreira and Luís Pereira are the beneficiaries of fellowships (SFRH/BD/25697/2005 and SFRH/BD/36764/2007, respectively) from the Foundation for Science and Technology, Portugal.
Author information
Authors and Affiliations
Corresponding author
Additional information
An erratum to this article can be found at http://dx.doi.org/10.1007/s11136-008-9393-7
Rights and permissions
About this article
Cite this article
Ferreira, P.L., Ferreira, L.N. & Pereira, L.N. How consistent are health utility values?. Qual Life Res 17, 1031–1042 (2008). https://doi.org/10.1007/s11136-008-9368-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11136-008-9368-8