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Bioavailability of Phenolic Antioxidants Associated with Dietary Fiber: Plasma Antioxidant Capacity After Acute and Long-Term Intake in Humans

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Abstract

Most studies on bioavailability of phenolic antioxidants are focused in foods and beverages in which they may be easily released from the food matrix, reaching a peak in plasma antioxidant capacity 1–2 h after the intake. However, plant foods contain significant amounts of polyphenols associated with dietary fiber. The aim of the present work was to seek the bioavailability of total phenolic antioxidants associated with dietary fiber by measuring plasma antioxidant capacity in human volunteers. An acute intake of 15 g of a dietary fiber rich in associated phenolic antioxidants in healthy volunteers (n = 10) increased antioxidant capacity of plasma in relation to a control group (n = 4), becoming significant 8 h after the intake. This shows that phenolic antioxidants associated with dietary fiber are at least partially bioavailable in humans, although dietary fiber appears to delay their absorption. No significant changes were observed after long-term intake (16 weeks, 34 subjects).

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Abbreviations

ABTS:

2,2′-azinobis-(3-etilbenzotiazolin-6-sulphonic) acid

FRAP:

ferric reducing/antioxidant power

GADF:

grape antioxidant dietary fiber

PA:

phenolic antioxidants

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Acknowledgements

The authors thank the Instituto de Análisis Clínicos of the Universidad Complutense de Madrid for the help in the blood extractions. The authors thank the volunteers for their cooperation along the study. The technical assistance of Mrs. Ma. Rosa Redondo is acknowledged. The present research was performed under the financial support of the Spanish Ministry of Education and Science (project AGL 2004-07579-C04-01/ALI). S. Arranz had an FPI scholarship from the Ministerio de Educación y Ciencia.

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Authors and Affiliations

  1. Department of Metabolism and Nutrition (ICTAN–CSIC), Calle José Antonio Novais, 10, 28040, Madrid, Spain

    Jara Pérez-Jiménez, Maria Tabernero, Sara Arranz, M. Elena Díaz-Rubio & Fulgencio Saura-Calixto

  2. Nutrition and Gastrointestinal Health Unit (CSIC/UCM), Universidad Complutense de Madrid (UCM), Madrid, Spain

    José Serrano, Luis García-Diz & Isabel Goñi

Authors
  1. Jara Pérez-Jiménez
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  2. José Serrano
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  3. Maria Tabernero
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  4. Sara Arranz
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  5. M. Elena Díaz-Rubio
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  6. Luis García-Diz
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  7. Isabel Goñi
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  8. Fulgencio Saura-Calixto
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Correspondence to Jara Pérez-Jiménez.

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Pérez-Jiménez, J., Serrano, J., Tabernero, M. et al. Bioavailability of Phenolic Antioxidants Associated with Dietary Fiber: Plasma Antioxidant Capacity After Acute and Long-Term Intake in Humans. Plant Foods Hum Nutr 64, 102–107 (2009). https://doi.org/10.1007/s11130-009-0110-7

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  • DOI: https://doi.org/10.1007/s11130-009-0110-7

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