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NSAIDs in paediatrics: caution with varicella!

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Abstract

Anti-inflammatory drugs have been suspected on several occasions to have promoted development of bacterial infection among varicella patients. Some countries have not implemented childhood varicella vaccination. Three cases in our hospital suggested the predisposing role of NSAIDs in varicella patient deterioration. Open access to these drugs widely increases their use and patient information should be continually provided in the medical offices and at dispensing pharmacy counters. Taking account of the benefit/risk balance and applying the simple precautionary principle, it would be appropriate to be cautious about the use of NSAIDs in the paediatric population.

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Authors and Affiliations

  1. Pharmacie, Hôpital Robert-Debré, APHP, 48 bd Sérurier, 75019, Paris, France

    L. Durand, O. Bourdon & S. Prot-Labarthe

  2. Pharmacie Clinique, Université Paris Descartes, Sorbonne Paris Cité, Paris, France

    L. Durand, O. Bourdon & S. Prot-Labarthe

  3. Réanimation pédiatrique, Hôpital Robert-Debré, APHP, Paris, France

    P. Sachs

  4. Pédiatrie Générale, Hôpital Robert-Debré, APHP, Paris, France

    C. Lemaitre & M. Lorrot

  5. Service de Pharmacologie Pédiatrique et Pharmacogénétique, Hôpital Robert-Debré, APHP, Paris, France

    J. Bassehila

  6. Laboratoire Educations et Pratiques de Santé, EA 3412, Université Paris 13, Sorbonne Paris Cité, Bobigny, France

    O. Bourdon

  7. INSERM, ECEVE U1123, Paris, France

    S. Prot-Labarthe

Authors
  1. L. Durand
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  2. P. Sachs
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  3. C. Lemaitre
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  4. M. Lorrot
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  5. J. Bassehila
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  6. O. Bourdon
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  7. S. Prot-Labarthe
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Correspondence to S. Prot-Labarthe.

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Durand, L., Sachs, P., Lemaitre, C. et al. NSAIDs in paediatrics: caution with varicella!. Int J Clin Pharm 37, 975–977 (2015). https://doi.org/10.1007/s11096-015-0184-2

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  • DOI: https://doi.org/10.1007/s11096-015-0184-2

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