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Unnecessary use of antibiotics for inpatient children with pneumonia in two counties of rural China

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Abstract

Objective To assess unnecessary use and cost of antibiotics for inpatient care for children under 14 years of age with pneumonia, and to identify the cost distribution in relation to different socio-economic status. Setting The study was hospital-based and cross-sectional. Method Between July 2007 and June 2008, 226 participants were interviewed in two county hospitals and three township health centers in two counties in rural China. The healthcare facilities provided medical and financial records for all study participants. Appropriateness of antibiotic treatment was assessed, in accordance with guidelines, by a paediatrician from a university teaching hospital, who reviewed all medical records. The cost of unnecessary antibiotics was based on the health facilities’ price lists. Results Unnecessary antibiotic prescriptions occurred in 43% of all patients. The median unnecessary cost of antibiotics was 40 RMB yuan (IQR: 22–100), and this extra cost increased the financial burden for the pneumonia inpatients by 18%. There were no statistically significant differences related to socio-economic categories for unnecessary antibiotics cost (F = 1.43, P = 0.2444). Conclusion Unnecessary prescribing of antibiotics use laid an extra burden on children with pneumonia at inpatient care. Implications for policy and practice might be considered regarding incentives, guidelines and training for health care providers.

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References

  1. Cars O, Hogberg LD, Murray M, Nordberg O, Sivaraman S, Lundborg CS, et al. Meeting the challenge of antibiotic resistance. Br Med J. 2008;337:a1438.

    Article  Google Scholar 

  2. WHO. The world health report 2007: a safer future: global public health security in the 21st century. Geneva: WHO Press; 2007.

  3. Reynolds L, McKee M. Factors influencing antibiotic prescribing in China: an exploratory analysis. Health Policy. 2009;90(1):32–6.

    Article  PubMed  Google Scholar 

  4. Hu S, Liu X, Peng Y. Assessment of antibiotic prescription in hospitalised patients at a Chinese university hospital. J Infect. 2003;46(3):161–3.

    Article  PubMed  Google Scholar 

  5. Liu X, Mills A. Evaluating payment mechanisms: how can we measure unnecessary care? Health Policy Plan. 1999;14(4):409–13.

    Article  PubMed  CAS  Google Scholar 

  6. Hopkins A. What do we mean by appropriate health care? Report of a working group prepared for the director of research and development of the NHS management executive. Qual Health Care. 1993;2(2):117–23.

    Article  Google Scholar 

  7. The Subspecialty Group of Respiratory Diseases, The Society of Pediatrics, Chinese Medical Association. Guidelines for management of childhood community acquired pneumonia (for trial implementation). Zhonghua Er Ke Za Zhi. 2007;45(2–3):83–90, 223–230.

  8. Wagstaff A, O’donnell O, Van doorslaer E, Lindelow M. Analyzing health equity using household survey data: a guide to techniques and their implementation. Washington: World Bank Publications; 2007.

    Google Scholar 

  9. Bonati M. Epidemiologic evaluation of drug use in children. J Clin Pharmacol. 1994;34(4):300–5.

    PubMed  CAS  Google Scholar 

  10. Zhang W, Liu X, Wang Y, Chen Y, Huang M, Fan M, et al. Antibiotic use in pulmonology wards of Chinese children’s hospitals: 2002–2006. J Clin Pharm Ther. 2009;34(1):61–5.

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

This publication is an output of the POVILL Consortium of ten research institutions in Asia and Europe (http://www.povill.com/en_index.aspx), supported by the Sixth Framework Programme of the European Commission. All partners participated in the design of studies.

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The Sixth Framework Programme of the European Commission (517657).

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No conflicts of interest to declare.

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Correspondence to Chenggang Jin.

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Liang, X., Jin, C., Wang, L. et al. Unnecessary use of antibiotics for inpatient children with pneumonia in two counties of rural China. Int J Clin Pharm 33, 750–754 (2011). https://doi.org/10.1007/s11096-011-9535-9

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  • DOI: https://doi.org/10.1007/s11096-011-9535-9

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