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Potentiometric Sensor for Benzylpenicillin Determination

  • STRUCTURE OF CHEMICAL COMPOUNDS, METHODS OF ANALYSIS AND PROCESS CONTROL
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Pharmaceutical Chemistry Journal Aims and scope

A potentiometric benzylpenicillin-sensitive sensor with a plasticized polyvinyl-chloride membrane was developed. The sensor contains a benzylpenicillin—rhodamine 6G ion pair. The response is linear for benzylpenicillin concentrations in the range 10–3 – 10–1M with an electrode-function slope characteristic of singly charged anions and a minimum detected concentration of (6.3 – 7.9) × 10–4 M. This sensor could be used to detect and determine benzylpenicillin in pharmaceuticals.

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Authors and Affiliations

  1. Lesya Ukrainka Eastern European National University, Lutsk, 43025, Ukraine

    Zh. A. Kormosh & N. A. Markovska

  2. Lutsk Basic Medical College, Lutsk, 43016, Ukraine

    N. N. Kormosh

Authors
  1. Zh. A. Kormosh
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  2. N. A. Markovska
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  3. N. N. Kormosh
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Correspondence to Zh. A. Kormosh.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 53, No. 6, pp. 62 – 64, June, 2019.

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Kormosh, Z.A., Markovska, N.A. & Kormosh, N.N. Potentiometric Sensor for Benzylpenicillin Determination. Pharm Chem J 53, 577–579 (2019). https://doi.org/10.1007/s11094-019-02040-w

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  • DOI: https://doi.org/10.1007/s11094-019-02040-w

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