Abstract
Several N-acyl phenothiazine chalcones were prepared by the condensation of various aldehydes with N-acyl phenothiazine in alcoholic KOH. The chalcones were further treated with urea and thiourea to obtain 6-(substituted phenyl)-4-(10H-phenothiazin-10-yl)pyrimidin-2(1H)-ones/thiones. All the synthesized compounds were screened for their antimicrobial activity and characterized by elemental analyses, IR, 1H NMR, and mass spectroscopy.
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Bansode, T.N., Rangari, R.P. & Shimpi, P.A. Synthesis and Biological Evaluation of Some Novel 6-(Substituted Phenyl)-4-(10H-Phenothiazin-10-YL)Pyrimidin-2(1H)-Ones/Thiones. Pharm Chem J 48, 430–433 (2014). https://doi.org/10.1007/s11094-014-1125-4
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DOI: https://doi.org/10.1007/s11094-014-1125-4