The kinetics of the production of paracetamol and oxaphenamide in the single-stage reductive acylation of p-nitrophenol on palladium-containing anionites in mild conditions were studied. Metal-polymer complexes were found to have high activity and selectivity. Target product yields were 48 – 90%.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
M. D. Mashkovskii, Medicines [in Russian], Novaya Volna, Moscow (2000), Vol. 1.
M. G. Abdullaev, Khim.-Farm. Zh., 36(6), 40 – 41 (2002).
M. G. Abdullaev, A. A. Nasibullin, and M. V. Klyuev, Zh. Obshch. Khim., 33(11), 1759 – 1760 (1997).
M. V. Klyuev, T. G. Volkova, and M. G. Abdullaev, Neftekhimiya, 42(1), 32 – 35 (2002).
M. V. Klyuev, M. G. Abdullaev, and A. A. Nasibullin, Neftekhimiya, 34(2), 185 – 187 (1994).
M. G. Abdullaev, Khim.-Farm. Zh., 35(1), 42 – 45 (2001).
M. V. Klyuev, M. G. Abdullaev, and Z. Sh. Abdullaeva, Khim.-Farm. Zh., 44(8), 31-37 (2010).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 47, No. 11, pp. 40 – 41, November, 2013.
Rights and permissions
About this article
Cite this article
Abdullaev, M.G., Abdullaeva, Z.S., Klyuev, M.V. et al. Kinetics of the Production of p-Acetaminophenol and p-Hydroxyphenylsalicylamide by Reductive Acylation of p-Nitrophenol on Palladium-Containing Anionites. Pharm Chem J 47, 610–611 (2014). https://doi.org/10.1007/s11094-014-1019-5
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11094-014-1019-5