Skip to main content
SpringerLink
Log in

Synthesis and Antimicrobial Activity of Complexes Based on 4-aryl-2-hydroxy-4-oxo-2-butenoic Acid N-heterylamides

  • Search for New Drugs
  • Published:
Pharmaceutical Chemistry Journal Aims and scope

Reaction of 4-aryl-2-hydroxy-4-oxo-2-butenoic acid N-hetarylamides with copper, zinc, and cadmium dichlorides led to the formation of bis[3-aryl-1-(N-hetaryl)carboxamido-1,3-propanedionato]copper,-zinc, and-cadmium, respectively. Compounds with high antimicrobial activity were found among these products.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Yu. S. Andreichikov, A. V. Milyutin, I. V. Krylova, et al., Khim.-farm. Zh., 24(7), 33–35 (1990).

    Google Scholar 

  2. A. V. Milyutin, L. R. Amirova, F. Ya. Nazmetdinov, et al., Khim.-farm. Zh., 30(6), 47–49 (1996).

    CAS  Google Scholar 

  3. A. V. Milyutin, L. R. Amirova, I. V. Krylova, et al., Khim.-farm. Zh., 31(1), 32–35 (1996).

    Google Scholar 

  4. N. A. Pulina, V. V. Zalesov, and P. A. Mokin, Bash. Khim. Zh., 14(3), 52–56 (2007).

    CAS  Google Scholar 

  5. V. V. Skopenko, V. M. Amirkhanov, T. Yu. Sliva, et al., Usp. Khim., 73(8), 797–813 (2004).

    Google Scholar 

  6. V. B. Prozoroskii, M. P. Prozorovskaya, and V. I. Demchenko, Farmakol. Toksikol., 4, 497–502 (1978).

    Google Scholar 

  7. R. U. Khabriev, ed., Methodical instructions for the study of the overall toxic activity of pharmacological compounds [in Russian], Meditsina, Moscow (2005), pp. 41–54.

    Google Scholar 

  8. V. P. Fisenko, ed., Handbook of Experimental (Preclinical) Study of New Pharmacological Compounds [in Russian], IIA Remedium, Moscow (2000), pp. 264–273.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Perm State Pharmaceutical Academy, Perm, Russia

    N. A. Pulina, P. A. Mokin, V. V. Yushkov, T. F. Odegova, M. V. Tomilov & K. V. Yatsenko

  2. Perm State University, Perm, Russia

    V. V. Zalesov

Authors
  1. N. A. Pulina
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. A. Mokin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. V. Yushkov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. V. V. Zalesov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. T. F. Odegova
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. M. V. Tomilov
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. K. V. Yatsenko
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 7, pp. 14–16, July, 2008.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pulina, N.A., Mokin, P.A., Yushkov, V.V. et al. Synthesis and Antimicrobial Activity of Complexes Based on 4-aryl-2-hydroxy-4-oxo-2-butenoic Acid N-heterylamides. Pharm Chem J 42, 389–391 (2008). https://doi.org/10.1007/s11094-008-0147-1

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11094-008-0147-1

Search

Navigation